scholarly journals An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

2016 ◽  
Vol 175 (5) ◽  
pp. 966-978 ◽  
Author(s):  
S. Thurneysen ◽  
P.F. Cheng ◽  
H.W. Nagel ◽  
M. Kunz ◽  
N. Jaberg-Bentele ◽  
...  
Keyword(s):  
Metabolic Activity ◽  
Exploratory Study ◽  
Cytokine Profile ◽  
Local Cytokine

Evaluation of the Systemic-Local Cytokine Profile in Patients with Pseudoexfoliation Syndrome

2017 ◽  
Vol 2 (3) ◽  
pp. 82-87
Author(s):  
N. Lutsenko ◽  
◽  
O. Isakova ◽  
O. Rudycheva ◽  
T. Mihalchik
Keyword(s):  
Cytokine Profile ◽  
Pseudoexfoliation Syndrome ◽  
Local Cytokine

Local cytokine profile in women with preterm birth due to premature rupture of membranes

2020 ◽  
Vol 15 (1) ◽  
pp. 43-47
Author(s):  
N.B. Kuznetsova ◽  
I.O. Bushtyreva ◽  
M.P. Dmitrieva ◽  
V.V. Barinova ◽  
V.S. Dybova
Keyword(s):  
Preterm Birth ◽  
Cytokine Profile ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Local Cytokine

Local cytokine profile in women with preterm birth due to premature rupture of membranes

2020 ◽  
Vol 15 (2) ◽  
pp. 80-84
Author(s):  
N.B. Kuznetsova ◽  
I.O. Bushtyreva ◽  
M.P. Dmitrieva ◽  
V.V. Barinova ◽  
V.S. Dybova
Keyword(s):  
Preterm Birth ◽  
Cytokine Profile ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Local Cytokine

scholarly journals Cellular actors, Toll-like receptors, and local cytokine profile in acute coronary syndromes

2010 ◽  
Vol 31 (12) ◽  
pp. 1457-1469 ◽  
Author(s):  
Christophe A. Wyss ◽  
Michel Neidhart ◽  
Lukas Altwegg ◽  
Katharina S. Spanaus ◽  
Keiko Yonekawa ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Cytokine Profile ◽  
Toll Like Receptors ◽  
Coronary Syndromes ◽  
Local Cytokine

scholarly journals A Distinct Cytokine Profile and Stromal Vascular Fraction Metabolic Status without Significant Changes in the Lipid Composition Characterizes Lipedema

2021 ◽  
Vol 22 (7) ◽  
pp. 3313
Author(s):  
Stefan Wolf ◽  
Jeremy W. Deuel ◽  
Maija Hollmén ◽  
Gunther Felmerer ◽  
Bong-Sung Kim ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Metabolic Activity ◽  
Lipid Composition ◽  
Subcutaneous Fat ◽  
Stromal Vascular Fraction ◽  
Cytokine Profile ◽  
Metabolic Phenotype ◽  
Low Grade ◽  
And Control ◽  
Low Grade Inflammation

Lipedema is an adipose tissue disorder characterized by the disproportionate increase of subcutaneous fat tissue in the lower and/or upper extremities. The underlying pathomechanism remains unclear and no molecular biomarkers to distinguish the disease exist, leading to a large number of undiagnosed and misdiagnosed patients. To unravel the distinct molecular characteristic of lipedema we performed lipidomic analysis of the adipose tissue and serum of lipedema versus anatomically- and body mass index (BMI)-matched control patients. Both tissue groups showed no significant changes regarding lipid composition. As hyperplastic adipose tissue represents low-grade inflammation, the potential systemic effects on circulating cytokines were evaluated in lipedema and control patients using the Multiplex immunoassay system. Interestingly, increased systemic levels of interleukin 11 (p = 0.03), interleukin 28A (p = 0.04) and interleukin 29 (p = 0.04) were observed. As cytokines can influence metabolic activity, the metabolic phenotype of the stromal vascular fraction was examined, revealing significantly increased mitochondrial respiration in lipedema. In conclusion, despite sharing a comparable lipid profile with healthy adipose tissue, lipedema is characterized by a distinct systemic cytokine profile and metabolic activity of the stromal vascular fraction.

scholarly journals Local cytokine profile in adults with acute diarrhea and its correction with immunomodulatory therapy

2018 ◽  
Vol 73 ◽  
pp. 160-161
Author(s):  
A. Aleshukina ◽  
N. Pshenichnaya ◽  
A. Buslenko ◽  
S. Khukazova ◽  
O. Kostenko ◽  
...  
Keyword(s):  
Acute Diarrhea ◽  
Cytokine Profile ◽  
Immunomodulatory Therapy ◽  
Local Cytokine
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