Three-dimensional high-definition optical coherence tomography image acquisition procedure for basal cell carcinoma

2015 ◽  
Vol 172 (4) ◽  
pp. 1153-1154 ◽  
Author(s):  
M. Boone ◽  
M. Suppa ◽  
M. Miyamoto ◽  
A. Marneffe ◽  
G.B.E. Jemec ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Image Acquisition ◽  
Three Dimensional ◽  
Optical Coherence Tomography Image ◽  
Optical Coherence ◽  
High Definition ◽  
Tomography Image

scholarly journals Diagnostic Value of Optical Coherence Tomography Image Features for Diagnosis of Basal Cell Carcinoma

2021 ◽  
Author(s):  
Fieke Adan ◽  
Klara Mosterd ◽  
Nicole W.J. Kelleners-Smeets ◽  
Patty J. Nelemans
Keyword(s):  
Optical Coherence Tomography ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Diagnostic Value ◽  
Image Features ◽  
Small Subset ◽  
Optical Coherence Tomography Image ◽  
Optical Coherence ◽  
Discriminative Ability

Optical coherence tomography (OCT) is a noninvasive diagnostic method. Numerous morphological OCT features have been described for diagnosis of basal cell carcinoma (BCC). In this study, we evaluate the diagnostic value of established features and we explore whether the use of a small set of features enables accurate discrimination between BCC and non-BCC lesions and between BCC subtypes. For each lesion, presence or absence of specific features was recorded. Histopathology was used as a gold standard. Diagnostic parameters were calculated for each feature and multivariate logistic regression analyses were performed to evaluate the loss in discriminative ability when using a small subset of features instead of all features that are characteristic for BCC according to literature. Results show that the use of a limited number of features allows for good discrimination of superficial BCC from non-superficial BCC and non-BCC lesions. The prevalence of BCC was 75.3% (225/299) and the proposed diagnostic algorithm enabled detection of 97.8% of BCC lesions (220/225). Subtyping without the need for biopsy was possible in 132 of 299 patients (44%) with a predictive value for presence of superficial BCC of 84.3% versus 98.8% for presence of non-superficial BCC.

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