Perspective: Aristotle on manic‐depressive illness and greatness

2020 ◽  
Vol 22 (6) ◽  
pp. 633-635
Author(s):  
S. Nassir Ghaemi
Keyword(s):  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive

Conditioning and Sensitisation in the Longitudinal Course of Affective Illness

1986 ◽  
Vol 149 (2) ◽  
pp. 191-201 ◽  
Author(s):  
Robert M. Post ◽  
David R. Rubinow ◽  
James C. Ballenger
Keyword(s):  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Conceptual Approach ◽  
Longitudinal Course ◽  
Behavioural Sensitisation ◽  
Affective Illness ◽  
Biological Variables ◽  
Manic Depressive ◽  
Progressive Course

Few biological theories of manic-depressive illness have focused on the longitudinal course of affective dysfunction and the mechanisms underlying its often recurrent and progressive course. The authors discuss two models for the development of progressive behavioural dysfunction—behavioural sensitisation and electrophysiological kindling—as they provide clues to important clinical and biological variables relevant to sensitisation in affective illness. The role of environmental context and conditioning in mediating behavioural and biochemical aspects of this sensitisation is emphasised. The sensitisation models provide a conceptual approach to previously inexplicable clinical phenomena in the longitudinal course of affective illness and may provide a bridge between psychoanalytic/psychosocial and neurobiological formulations of manic-depressive illness.

Transmission of Manic-Depressive Illness

JAMA ◽  
1973 ◽  
Vol 224 (8) ◽  
pp. 1187 ◽  
Author(s):  
Julien Mendlewicz
Keyword(s):  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive

Lack of association between manic-depressive illness and a highly polymorphic marker from GABRA3 gene

1995 ◽  
Vol 60 (5) ◽  
pp. 434-435 ◽  
Author(s):  
Rosa Puertollano ◽  
Gillermo Visedo ◽  
Jerónimo Saiz-Ruiz ◽  
Consuelo Llinares ◽  
José Fernández-Piqueras
Keyword(s):  
Polymorphic Marker ◽  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive
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