scholarly journals From Risk to Illness: Tracking Young People at Increased Familial Risk of Bipolar Disorder (From the Prospective Offspring Studies and Treatment Trials (POST) Task Force)

2017 ◽  
Vol 19 ◽  
pp. 13-14
Keyword(s):  
Bipolar Disorder ◽  
Young People ◽  
Task Force ◽  
Familial Risk ◽  
Treatment Trials

M49 EPIGENOME-WIDE ASSOCIATION STUDY (EWAS) OF YOUNG PEOPLE WITH FAMILIAL RISK OF BIPOLAR DISORDER

2019 ◽  
Vol 29 ◽  
pp. S192
Author(s):  
Sonia Hesam-Shariati ◽  
Bronwyn Overs ◽  
Claudio Toma ◽  
Oliver Watkeys ◽  
Melissa Green ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Young People ◽  
Association Study ◽  
Familial Risk

scholarly journals Interhemispheric white matter integrity in young people with bipolar disorder and at high genetic risk

2016 ◽  
Vol 46 (11) ◽  
pp. 2385-2396 ◽  
Author(s):  
G. Roberts ◽  
W. Wen ◽  
A. Frankland ◽  
T. Perich ◽  
E. Holmes-Preston ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
White Matter ◽  
Young People ◽  
Age Of Onset ◽  
Familial Risk ◽  
The Novel ◽  
Course Of Illness ◽  
High Genetic Risk ◽  
History Of ◽  
Recurrent Major Depressive Disorder

BackgroundWhite matter (WM) impairments have been reported in patients with bipolar disorder (BD) and those at high familial risk of developing BD. However, the distribution of these impairments has not been well characterized. Few studies have examined WM integrity in young people early in the course of illness and in individuals at familial risk who have not yet passed the peak age of onset.MethodWM integrity was examined in 63 BD subjects, 150 high-risk (HR) individuals and 111 participants with no family history of mental illness (CON). All subjects were aged 12 to 30 years.ResultsThis young BD group had significantly lower fractional anisotropy within the genu of the corpus callosum (CC) compared with the CON and HR groups. Moreover, the abnormality in the genu of the CC was also present in HR participants with recurrent major depressive disorder (MDD) (n = 16) compared with CON participants.ConclusionsOur findings provide important validation of interhemispheric abnormalities in BD patients. The novel finding in HR subjects with recurrent MDD – a group at particular risk of future hypo/manic episodes – suggests that this may potentially represent a trait marker for BD, though this will need to be confirmed in longitudinal follow-up studies.

Default mode network in young people with familial risk for psychosis — The Oulu Brain and Mind Study

2013 ◽  
Vol 143 (2-3) ◽  
pp. 239-245 ◽  
Author(s):  
Tuomas Jukuri ◽  
Vesa Kiviniemi ◽  
Juha Nikkinen ◽  
Jouko Miettunen ◽  
Pirjo Mäki ◽  
...  
Keyword(s):  
Young People ◽  
Default Mode Network ◽  
Familial Risk ◽  
Default Mode

Increased Waking Salivary Cortisol Levels in Young People at Familial Risk of Depression

2007 ◽  
Vol 164 (4) ◽  
pp. 617-621 ◽  
Author(s):  
Zola N. Mannie ◽  
Catherine J. Harmer ◽  
Philip J. Cowen
Keyword(s):  
Young People ◽  
Salivary Cortisol ◽  
Familial Risk ◽  
Cortisol Levels

scholarly journals Delphi survey of maintenance lithium treatment in older adults with bipolar disorder: An ISBD task force report

2018 ◽  
Vol 21 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Kenneth I. Shulman ◽  
Osvaldo P. Almeida ◽  
Nathan Herrmann ◽  
Ayal Schaffer ◽  
Sergio A. Strejilevich ◽  
...  
Keyword(s):  
Older Adults ◽  
Bipolar Disorder ◽  
Task Force ◽  
Lithium Treatment ◽  
Delphi Survey ◽  
Task Force Report
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