scholarly journals A review of the prescribing trend of thiazide‐type and thiazide‐like diuretics in hypertension: A UK perspective

2019 ◽  
Vol 85 (12) ◽  
pp. 2707-2713
Author(s):  
Ryan J. McNally ◽  
Franca Morselli ◽  
Bushra Farukh ◽  
Philip J. Chowienczyk ◽  
Luca Faconti
Keyword(s):  
Prescribing Trend

scholarly journals Drug utilization audit of antipsychotics using WHO methodology: recommendations for rational prescribing

2018 ◽  
Vol 7 (10) ◽  
pp. 2021
Author(s):  
Iram Shaifali ◽  
Rajib Karmakar ◽  
Shalini Chandra ◽  
Santosh Kumar
Keyword(s):  
Drug Utilization ◽  
Atypical Antipsychotics ◽  
Essential Medicine ◽  
Uttar Pradesh ◽  
Cross Sectional ◽  
Prescribing Indicators ◽  
Male Predominance ◽  
Rational Prescribing ◽  
Prescribing Trends ◽  
Prescribing Trend

Background: Utilization pattern of antipsychotics has undergone a major shift as the newly introduced atypical antipsychotics have heralded the market. Hence continuous studies on current prescribing trends are needed to provide most updated, effective and rational treatment of psychoses.Methods: This cross-sectional prospective study was conducted at Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India. OPD tickets of the department of psychiatry for the year 2016-2017 were evaluated for a total of 310 cases. These prescriptions were used to determine the drug utilization of antipsychotics and for their appropriateness against the WHO recommended core prescribing indicators.Results: A total of 310 patients satisfied the inclusion criteria and a male predominance was seen (male:female= 1.3:1). The most common psychotic disorder diagnosed was schizophrenia (44%). Majority of the patients (76%) received monotherapy and the prescribing trend showed a higher use of atypical antipsychotics (89%) over typical ones (11%). The most commonly prescribed anti-psychotic drugs were olanzapine (31%), followed by risperidone (26%). On analysing prescriptions according to the WHO core prescribing indicators it was observed that average number of antipsychotics prescribed per prescription was 1.32. 24% of drugs were prescribed by generic name and 5.2% were administered via injectable route. Drugs prescribed from National list of Essential Medicine, 2015 constituted 46%.Conclusions: The high inclination towards the use of atypical antipsychotics observed in our study correlates with the global changing trends in the treatment of schizophrenia. WHO prescribing indicators should be adhered to, to impart rational prescribing.

scholarly journals Prescribing Trend of Antirheumatic Drugs in Taiwan and Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis: A Nationwide Cohort Study

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Chien-Ying Lee ◽  
Chih-Jaan Tai ◽  
Ya-Fang Tsai ◽  
Yu-Hsiang Kuan ◽  
Chiu-Hsiang Lee ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Chronic Kidney Disease ◽  
Cohort Study ◽  
Kidney Disease ◽  
Control Group ◽  
Research Database ◽  
Antirheumatic Drugs ◽  
Prescribing Trend

We aimed to investigate the prescribing trend of antirheumatic drugs and assess the risk of cardiovascular disease in patients with rheumatoid arthritis in Taiwan. This study was a retrospective cohort study, conducted based on the Taiwan National Health Insurance Research Database. The study subjects were 15,366 new rheumatoid arthritis patients from 2003 to 2010. To avoid selection bias, we applied propensity score matching to obtain general patients, as the control group. Cox proportional hazard model was used to evaluate the risk of cardiovascular disease in rheumatoid arthritis patients. The most common prescriptions of rheumatoid arthritis were nonsteroidal anti-inflammatory drugs. After controlling for related variables, rheumatoid arthritis patients had a higher risk of cardiovascular disease than general patients (adjusted hazard ratio [aHR] = 1.31; 95% confidence interval [CI]: 1.23-1.39). Age was the most significantly associated risk factor with the cardiovascular disease. Other observed risk factors for cardiovascular disease included hypertension (aHR = 1.57, 95% CI: 1.48-1.65), diabetes mellitus (aHR = 1.47, 95% CI: 1.38-1.57), and chronic kidney disease (aHR = 1.48, 95% CI: 1.31-1.66). Patients with rheumatoid arthritis indeed had a higher risk of incident cardiovascular diseases. Besides, age, hypertension, diabetes mellitus, and chronic kidney disease were also associated with a higher risk of cardiovascular disease.

Temporal changes in antihypertensive prescribing trend in Bahrain over a decade: emerging issues in iatrogenic sexual dysfunction

2014 ◽  
Vol 52 (03) ◽  
pp. 245-254
Author(s):  
Awatif H.H. Damanhori ◽  
Khalid A.J. Al Khaja ◽  
Reginald P. Sequeira ◽  
Alwaleed K. Alkhaja
Keyword(s):  
Sexual Dysfunction ◽  
Temporal Changes ◽  
Emerging Issues ◽  
Prescribing Trend

scholarly journals PRESCRIBING TREND AMONG HOSPITALIZED PEDIATRIC PATIENTS IN PRIVATE SECTOR HOSPITAL: A PROSPECTIVE OBSERVATIONAL STUDY IN NADIAD, INDIA

2020 ◽  
pp. 195-198
Author(s):  
SANDIP B PATEL ◽  
YASH P PATEL ◽  
SHISHAV B SHAH
Keyword(s):  
Private Sector ◽  
Pediatric Patients ◽  
Indian Academy ◽  
Essential Medicines ◽  
World Health ◽  
Common Disease ◽  
Treatment Protocols ◽  
Study Results ◽  
Prescribing Trend ◽  
Health Organization

Objectives: Purpose of this study was to analyze the prescription pattern among the hospitalized pediatric patients in private sector hospital. Methods: The study was conducted from January 2018 to April, 2018 at Shaishav Hospital, Nadiad, Gujarat, India, and 178 patients were included into the study. Results were obtained by applying the World Health Organization (WHO) prescribing indicators as well as Indian Academy of Pediatrics List of Essential Medicines (IAP-LEM). Results: During the study period, infectious disease such as pneumonitis, bronchitis, enteric fever, gastroenteritis, and dehydration were the dominant disease among the patients. Average number of drugs per prescription was four but in many of prescription, poly-pharmacy has shown. Antibiotic agents were the most prescribed drug (38.6%) among different classes of drugs. Use of the parenteral route of drug administration was used beyond the range stated by the WHO (59% prescriptions vs. 13–24% WHO range). We found that doctor followed IAP-LEM (in 99.78% cases) for prescribing as well as for dosing also, which was very impressive. Conclusions: As this study indicates, there is a need of development of evidence-based treatment protocols for common disease condition for the rational use of medication, especially for an antibiotic medication.

scholarly journals Prescribing trend in cardiovascular patients at Ethiopian university hospital: The number of medications and implication on the clinical improvement

2019 ◽  
Vol 7 (3) ◽  
pp. e00474 ◽  
Author(s):  
Yonas G. Tefera ◽  
Tamrat B. Abebe ◽  
Abebe B. Mekuria ◽  
Misganaw S. Kelkay ◽  
Tadesse M. Abegaz
Keyword(s):  
Clinical Improvement ◽  
University Hospital ◽  
Cardiovascular Patients ◽  
Prescribing Trend

scholarly journals The prescribing trend of oral antidiabetic agents for type 2 diabetes in Taiwan

Medicine ◽  
2017 ◽  
Vol 96 (43) ◽  
pp. e8257 ◽  
Author(s):  
Wei-Min Chu ◽  
Hsin-En Ho ◽  
Kuang-Hua Huang ◽  
Yu-Tse Tsan ◽  
Yi-Sheng Liou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Oral Antidiabetic Agents ◽  
Antidiabetic Agents ◽  
Oral Antidiabetic ◽  
Prescribing Trend

scholarly journals Proton Pump inhibitor prescribing trend in the us Ambulatory setting

2015 ◽  
Vol 18 (3) ◽  
pp. A265 ◽  
Author(s):  
P. Rane ◽  
R.R. Aparasu ◽  
S. Guha
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Ambulatory Setting ◽  
The Us ◽  
Prescribing Trend

scholarly journals Coronary artery disease prescribing pattern and risk factor assessment in the patients undergoing angioplasty

2021 ◽  
Vol 10 (5) ◽  
pp. 517
Author(s):  
Nilay D. Solanki ◽  
Nisha Patel ◽  
Shubha Desai ◽  
Varsha Patel
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Prescribing Pattern ◽  
Patient Counselling ◽  
Case Record ◽  
Prescribing Trends ◽  
History Of ◽  
Artery Disease ◽  
Prescribing Trend

Background: Coronary artery disease is caused by an obstruction in vascular supply to the heart. Angioplasty is a frequently used intervention for the management of CAD patients. Supportive and preventive therapies are additionally provided to these patients. Objective of current study was to assess the associated risk factors as well as prescribing trends in CAD patients.Methods: A prospective study was conducted in 88 patients undergoing coronary angioplasty. Patients were assessed for risk factors of CAD. Medication history of patients was recorded in case record form for analysis of prescribing trend and its rationality. Data were statistically analyzed using prism software.Results: In present study most of the CAD patients were male (80.68%) and mean age of patient was 59.19 years. Majority of patients (39.77%) were in age range of 61-70 years. Most common associated conditions at admission were hypertension and diabetes. In this study, BMI, stress, lack of exercise, hypertension, diabetes, family history of CVD were risk factors of CAD and significant correlation observed with risk factors and coronary artery disease. (p<0.05) Frequently prescribed drugs were antiplatelet, antibiotics, antihypertensive, antiulcer, antihyperlipidemic, antidiabetic agents. In 19.31% cases, drug interaction was detected out of which two cases recorded severe. Medical stents coated with everolimus, sirolimus were also prescribed.Conclusions: It was concluded that history of cardiovascular disease, hypertension, diabetes are major risk factors of CAD. Certain level of irrationality in the prescribing trend was observed. Proper patient counselling and care can help in preventing CAD and reduces health burden.

scholarly journals Managing the misuse potential and risk of psychological harm from gabapentinoids in primary care in New Zealand

2021 ◽  
Vol 13 (4) ◽  
pp. 302
Author(s):  
Shaun Aindow ◽  
Rose Crossin ◽  
Les Toop ◽  
Ben Hudson
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
New Zealand ◽  
Current Knowledge ◽  
International Literature ◽  
Knowledge Gaps ◽  
Suicidal Thoughts ◽  
International Evidence ◽  
Psychological Harm ◽  
Prescribing Trend

ABSTRACTGabapentinoid prescribing is increasing in New Zealand. International evidence suggests that this prescribing trend is followed by increasing harms, including misuse, dependence, overdose, and psychological harms including suicidal thoughts or behaviours. However, there is limited guidance for prescribers on how to manage these potential harms. Here, we summarise the current international literature and identify three main risk factors that can be used for screening purposes when considering prescribing a gabapentinoid, to identify patients that may be at greater risk of harm. Based on current knowledge of harms, we provide guidance to prescribers on monitoring patients taking gabapentinoids. Finally, we summarise the evidence regarding tapering, and highlight key knowledge gaps including other interventions, referral, and data from primary care populations.

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