scholarly journals Reversal of mecamylamine-induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses

2018 ◽  
Vol 84 (5) ◽  
pp. 888-899 ◽  
Author(s):  
Ricardo Alvarez-Jimenez ◽  
Ellen P. Hart ◽  
Samantha Prins ◽  
Marieke de Kam ◽  
Joop M.A. van Gerven ◽  
...  
2015 ◽  
Vol 29 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Sonja Schumacher ◽  
Uwe Herwig ◽  
Volker Baur ◽  
Christoph Mueller-Pfeiffer ◽  
Chantal Martin-Soelch ◽  
...  

The present study sought to investigate peripheral physiological responses to the anticipation of explicitly and ambiguously cued emotional pictures. Emotionally positive and negative as well as neutral pictures were presented to 32 healthy subjects. At the beginning of an anticipation period they were cued about the valence of the upcoming picture (neutral, positive, negative, or ambiguous). Skin conductance, heart rate, and zygomaticus and corrugator electromyogram responses were measured during anticipation and perception. Responses specific to the emotional conditions were observed during anticipation as well as during perception. During the anticipation of ambiguously cued pictures, responses were similar to responses elicited by anticipating negative pictures. In line with results from brain imaging studies, peripheral physiological responses could be interpreted to reflect a negative bias for ambiguous events.


2010 ◽  
Vol 25 (6) ◽  
pp. 909-912 ◽  
Author(s):  
Haruka OZAWA ◽  
Takashi MATSUZAKI ◽  
Yuito NAKAYAMA ◽  
Hideto NAKAYAMA ◽  
Noriaki TAKAHASHI ◽  
...  

2013 ◽  
Vol 177 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Olli-Pekka Piira ◽  
Johanna A. Miettinen ◽  
Arto J. Hautala ◽  
Heikki V. Huikuri ◽  
Mikko P. Tulppo

2005 ◽  
Vol 8 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Pedro Montoya ◽  
J. Javier Campos ◽  
Rainer Schandry

Cardiodynamic and hemodynamic reactions to emotion-eliciting film sequences were investigated. Thirty-two healthy subjects (12 women, 20 men) were randomly assigned to one of two groups. In the first group, anger was induced using selected scenes of the film “Ragtime.” In the second group, scenes of the film “The Shining” were chosen to elicit fear. A documentary film was used as a baseline stimulus in both groups. EKG, impedance cardiography, and blood pressure were continuously monitored. The two emotional conditions elicited significant differential changes in subjective ratings and cardiovascular indices. Fear was associated with decreased cardiac output, increased total peripheral resistance, and a reduction in stroke volume and myocardial contractility. Anger was associated with an increase of cardiac output and small changes in total peripheral resistance. These results support the hypothesis that discrete emotions such as fear and anger elicit differential patterns of physiological responses.


2011 ◽  
Vol 26 (2) ◽  
pp. 231-234
Author(s):  
Haruka OZAWA ◽  
Takashi MATSUZAKI ◽  
Yuito NAKAYAMA ◽  
Hideto NAKAYAMA ◽  
Noriaki TAKAHASHI ◽  
...  

2014 ◽  
Vol 32 (1) ◽  
pp. 28-36 ◽  
Author(s):  
David T W Yu ◽  
Alice Y M Jones

Background Transcutaneous electrical nerve stimulation over acupuncture points (acu-TENS) has been reported to improve clinical outcomes. The objectives of the present study were to investigate whether acupuncture point sensations were experienced during acu-TENS, and whether such sensations were associated with any concomitant changes in autonomic nervous system activity. Methods This study adopted a single-blinded, randomised, controlled trial methodology. A total of 36 healthy subjects were randomly assigned to an experimental group (acu-TENS on right LI4 and LI11 points); control group (acu-TENS to bilateral kneecaps); or placebo group (sham acu-TENS on right LI4 and LI11 points). Heart rate (HR), mean arterial blood pressure (MAP), SD of the NN interval (SDNN) and low frequency to high frequency ratio (LF/HF) were measured before, during and after intervention. The Hong Kong Chinese version of the Massachusetts General Hospital Acupuncture Sensation Scale (C-MMASS) index was used for quantifying the acupuncture point stimulation sensations. Results The experimental group showed a significant increase in HR (mean (SD) 73.5 (6.3) to 75.9 (6.7) bpm, p=0.027), MAP (88.5 (4.5) to 91.0 (4.1) mm Hg, p=0.004), SDNN (143.36 (8.58) to 153.69 (7.64) ms, p=0.002) and LF/HF (1.26 (0.19) to 1.31 (0.21), p=0.037) during the intervention. The control group showed a significant increase in SDNN (140.21 (8.72) to 143.39 (9.47) ms, p=0.009) and LF/HF (1.21 (0.09) to 1.23 (0.12), p=0.033). There were no significant physiological changes in the placebo group. Overall C-MMASS indices for the experimental, control and placebo groups were 3.23 (0.3), 2.14 (0.6) and 0.29 (0.32), respectively. The between-group difference was statistically significant (F=139.24, df=2, p<0.05). However, correlation analysis did not support any association between sensation intensity and physiological responses in any groups (γ ranged from −0.36 to 0.25). Conclusions This study showed that ‘acupuncture point sensations’ were experienced during acu-TENS to LI4 and LI11, but such sensations were not associated with physiological responses induced during the stimulation.


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