Effect of probiotic supplementation on growth performance, intestinal morphology, barrier integrity, and inflammatory response in broilers subjected to cyclic heat stress

2020 ◽  
Vol 91 (1) ◽  
Author(s):  
Qiufen Li ◽  
Gen Wan ◽  
Chengying Peng ◽  
Lanjiao Xu ◽  
Yingmei Yu ◽  
...  
Keyword(s):  
Heat Stress ◽  
Inflammatory Response ◽  
Growth Performance ◽  
Intestinal Morphology ◽  
Probiotic Supplementation ◽  
Barrier Integrity ◽  
Cyclic Heat

252 Effect of Cyclic Heat Stress and Supplemented Inorganic and Organic Zinc Source Levels on Grow-Finish Pig Growth Performance and Estimated Body Composition.

2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 134-135 ◽  
Author(s):  
K M Mills ◽  
J A Feldpausch ◽  
A W Duttlinger ◽  
S K Elefson ◽  
S M Zuelly ◽  
...  
Keyword(s):  
Body Composition ◽  
Heat Stress ◽  
Growth Performance ◽  
Zinc Source ◽  
Organic Zinc ◽  
Cyclic Heat ◽  
Inorganic And Organic

Effect of chronic cyclic heat stress on the intestinal morphology, oxidative status and cecal bacterial communities in broilers

2020 ◽  
Vol 91 ◽  
pp. 102619
Author(s):  
Guanhui Liu ◽  
Haibo Zhu ◽  
Tenghe Ma ◽  
Zhaoyang Yan ◽  
Yongying Zhang ◽  
...  
Keyword(s):  
Heat Stress ◽  
Bacterial Communities ◽  
Oxidative Status ◽  
Intestinal Morphology ◽  
Cyclic Heat

scholarly journals Effects of Herbal Adaptogen Feed-Additive on Growth Performance, Carcass Parameters, and Muscle Amino Acid Profile in Heat-Stressed Modern Broilers

2021 ◽  
Vol 12 ◽  
Author(s):  
Elizabeth S. Greene ◽  
Clay Maynard ◽  
Casey M. Owens ◽  
Jean-François Meullenet ◽  
Sami Dridi
Keyword(s):  
Body Weight ◽  
Heat Stress ◽  
Amino Acid ◽  
Growth Performance ◽  
Feed Intake ◽  
Control Diet ◽  
Amino Acid Profile ◽  
Poultry Production ◽  
Carcass Parameters ◽  
Cyclic Heat

Heat stress has strong adverse effects on poultry production and, thereby, threats its sustainability, which energized scientists to search for innovative and effective solutions. Here, we undertook this study to evaluate the effects of in-feed herbal adaptogen (stress response modifier) supplementation on growth performances, meat quality, and breast amino acid profile in chronic cyclic heat-stressed broilers. Day-old male Cobb 500 chicks (n = 720) were randomly assigned, in environmental chambers (n = 12, 24 pens), to three diet-treatments: a three-phase corn-soybean based diet fed as such (Control, C), or supplemented with the herbal adaptogen at 500 g/1000 kg control diet (NR-PHY-500) or at 1 kg/1000 kg control diet (NR-PHY-1000). From d29 to d42, birds from 9 chambers were exposed to cyclic heat stress (HS, 35°C from 9:30 am-5:30 pm), however, the rest of the chamber were maintained at thermoneutral conditions (24°C, TN), which creates 4 experimental groups: C-TN, C-HS, NR-PHY-500HS, and NR-PHY-1000HS (6 pens/group, 168 birds/group). HS altered growth performance via depression of feed intake and body weight. Adaptogen supplementation stimulated feed intake and averaged 65.95 and 83.25 g better body weight and 5 and 10 points better FCR at low and high dose, respectively, compared to heat-stressed birds. This increase in body weight was mirrored in enhanced weights of body parts (breast, tender, wings, and legs). Adaptogen supplementation modulated also breast amino acid profile, pH, color, and quality. Together, these data suggested that adaptogen supplementation could be a promising solution to alleviate heat stress, however further in-depth investigation for its mode of action and its underlying mechanisms are warranted.

scholarly journals Dietary Fiber Ameliorates Lipopolysaccharide-Induced Intestinal Barrier Function Damage in Piglets by Modulation of Intestinal Microbiome

mSystems ◽  
2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Xiao Sun ◽  
Yalei Cui ◽  
Yingying Su ◽  
Zimin Gao ◽  
Xinying Diao ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Growth Performance ◽  
Proinflammatory Cytokines ◽  
Barrier Function ◽  
Intestinal Microflora ◽  
Intestinal Barrier ◽  
Intestinal Morphology ◽  
Intestinal Barrier Function ◽  
Tnf Α

ABSTRACT Weaning of piglets is accompanied by intestinal inflammation, impaired intestinal barrier function, and intestinal microflora disorder. Regulating intestinal microflora structure can directly or indirectly affect intestinal health and host growth and development. However, whether dietary fiber (DF) affects the inflammatory response and barrier function by affecting the intestinal microflora and its metabolites is unclear. In this study, we investigated the role of intestinal microflora in relieving immune stress and maintaining homeostasis using piglets with lipopolysaccharide (LPS)-induced intestinal injury as a model. DF improved intestinal morphology and barrier function, inhibited the expression of inflammatory signal pathways (Toll-like receptor 2 [TLR2], TLR4, and NF-κB) and proinflammatory cytokines (interleukin 1β [IL-1β], IL-6, and tumor necrosis factor alpha [TNF-α]), and upregulated the expression of barrier-related genes (encoding claudin-1, occludin, and ZO-1). The contents of proinflammatory cytokines (IL-1β, IL-6, and TNF-α) and the activity of diamine oxidase in plasma were decreased. Meanwhile, DF had a strong effect on the composition and function of intestinal microflora at different taxonomic levels, the relative abundances of cellulolytic bacteria and anti-inflammatory bacteria were increased, and the concentrations of propionate, butyrate, and total short-chain fatty acids (SCFAs) in intestinal contents were increased. In addition, the correlation analysis also revealed the potential relationship between metabolites and certain intestinal microflora, as well as the relationship between metabolites and intestinal morphology, intestinal gene expression, and plasma cytokine levels. These results indicate that DF improves intestinal barrier function, in part, by altering intestinal microbiota composition and increasing the synthesis of SCFAs, which subsequently alleviate local and systemic inflammation. IMPORTANCE Adding DF to the diet of LPS-challenged piglets alleviated intestinal and systemic inflammation, improved intestinal barrier function, and ultimately alleviated the growth retardation of piglets. In addition, the addition of DF significantly increased the relative abundance of SCFA-producing bacteria and the production of SCFAs. We believe that the improvement of growth performance of piglets with LPS-induced injury can be attributed to the beneficial effects of DF on intestinal microflora and SCFAs, which reduced the inflammatory response in piglets, improving intestinal barrier function and enhancing body health. These research results provide a theoretical basis and guidance for the use of specific fiber sources in the diet to improve intestinal health and growth performance of piglets and thus alleviate weaning stress. Our data also provide insights for studying the role of DF in regulating gastrointestinal function in human infants.

scholarly journals 356 Young Scholar Presentation: An applied approach to studying heat stress: Effects of cyclic heat and zinc supplementation on body temperature, gut health, and pork quality

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 144-144
Author(s):  
Julie A Feldpausch ◽  
Kayla M Mills ◽  
Alan W Duttlinger ◽  
S M Elly ◽  
Yuan H B Kim ◽  
...  
Keyword(s):  
Heat Stress ◽  
Zinc Supplementation ◽  
Carcass Composition ◽  
Intestinal Morphology ◽  
Carcass Quality ◽  
Pork Quality ◽  
Gut Health ◽  
Minimal Impact ◽  
Cyclic Heat ◽  
The Impact

Abstract Heat stress (HS) has depletory effects on intestinal morphology, induces metabolic changes, and disposes pigs to oxidative stress. Zinc has roles in gut health, nutrient and insulin mediated metabolism. To better understand the effects of cyclic heat and dietary Zn supplementation on gut integrity, carcass composition, and pork quality, commercial crossbred mixed-sex pigs (n = 400; initially 72.2 kg) were housed under either thermoneutral (TN; 18.9–16.7°C) or cycling HS conditions simulating chronic summer heat (30°C/26.7°C for 12h:12h on days 24–65) with acute heat periods of 32-33°C/29-30°C for 12h:12h on days 21–24, 42–45, and 63–65. Treatments were arranged in a 2×2×2 factorial with main effects of environment (HS vs. TN), added Zn level (50 vs. 130 mg/kg available Zn), and added Zn source (inorganic from ZnO vs. organic from Availa®Zn; Zinpro Corp, Eden Prairie, MN). Relative to TN, HS elevated (P < 0.050) body temperatures during the growing period. Heat stress was correlated with ileal villus height (r=-0.51, P = 0.015) and HSP-70 expression (r=0.46, P = 0.041). Growth was reduced such that carcasses from HS pigs were lighter (P = 0.011) and exhibited improved carcass quality with higher (P = 0.001) 24-hour loin pH, decreased (P = 0.034) drip loss, and greater (P < 0.050) subjective color and firmness scores compared to TN carcasses. Relative to TN, loin chops and sausage patties manufactured from the HS carcasses had similar oxidative stability (CIE L*a*b* color, 2-thiobarbituric acid reactive substances) throughout a 10-day simulated retail display. The HS induced fatty acid profile differences in the pork product but were not sufficient to shift IV (P > 0.10). Belly firmness and slice lean were also unaffected (P > 0.10) by HS. Zinc supplementation had minimal impact on the carcass quality characteristics studied. Further research is necessary to better understand the impact of HS duration, combination with additional stressors, and refine the ability to utilize thermal monitoring to manage negative impacts of HS.

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