scholarly journals Derivation and validation of a cardiovascular risk score for prediction of major acute cardiovascular events in non-alcoholic fatty liver disease; the importance of an elevated mean platelet volume

2019 ◽  
Vol 49 (8) ◽  
pp. 1077-1085 ◽  
Author(s):  
Robin D. Abeles ◽  
Benjamin H. Mullish ◽  
Roberta Forlano ◽  
Torben Kimhofer ◽  
Maciej Adler ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Liver Disease ◽  
Fatty Liver ◽  
Mean Platelet Volume ◽  
Fatty Liver Disease ◽  
Cardiovascular Events ◽  
Platelet Volume ◽  
Alcoholic Fatty Liver ◽  
Cardiovascular Risk Score ◽  
Alcoholic Fatty Liver Disease

scholarly journals Cardiovascular Risk in Non-Alcoholic Fatty Liver Disease: Mechanisms and Therapeutic Implications

2019 ◽  
Vol 16 (17) ◽  
pp. 3104 ◽  
Author(s):  
Claudio Tana ◽  
Stefano Ballestri ◽  
Fabrizio Ricci ◽  
Angelo Di Vincenzo ◽  
Andrea Ticinesi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Cardiovascular Events ◽  
Alcoholic Fatty Liver ◽  
The Metabolic Syndrome ◽  
Increased Risk ◽  
Alcoholic Fatty Liver Disease

New evidence suggests that non-alcoholic fatty liver disease (NAFLD) has a strong multifaceted relationship with diabetes and metabolic syndrome, and is associated with increased risk of cardiovascular events, regardless of traditional risk factors, such as hypertension, diabetes, dyslipidemia, and obesity. Given the pandemic-level rise of NAFLD—in parallel with the increasing prevalence of obesity and other components of the metabolic syndrome—and its association with poor cardiovascular outcomes, the question of how to manage NAFLD properly, in order to reduce the burden of associated incident cardiovascular events, is both timely and highly relevant. This review aims to summarize the current knowledge of the association between NAFLD and cardiovascular disease, and also to discuss possible clinical strategies for cardiovascular risk assessment, as well as the spectrum of available therapeutic strategies for the prevention and treatment of NAFLD and its downstream events.

Mean platelet volume in biopsy-proven non-alcoholic fatty liver disease

Platelets ◽  
2012 ◽  
Vol 24 (3) ◽  
pp. 194-199 ◽  
Author(s):  
Mehmet Celikbilek ◽  
Sebnem Gürsoy ◽  
Kemal Deniz ◽  
Ahmet Karaman ◽  
Gökmen Zararsiz ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Mean Platelet Volume ◽  
Fatty Liver Disease ◽  
Platelet Volume ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease
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