scholarly journals The use of prophylactic gastroprotective therapy in patients with nonsteroidal anti-inflammatory drug- and aspirin-associated ulcer bleeding: a cross-sectional study

2013 ◽  
Vol 37 (8) ◽  
pp. 819-824 ◽  
Author(s):  
C. W. Ho ◽  
Y. K. Tse ◽  
B. Wu ◽  
C. J. J. Mulder ◽  
F. K. L. Chan
Keyword(s):  
Cross Sectional Study ◽  
Ulcer Bleeding ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Cross-Sectional Study for Prevalence of Non-Steroidal Anti-Inflammatory Drug-Induced Gastrointestinal, Cardiac and Renal Complications in India: Interim Report

2015 ◽  
Vol 8 (3-4) ◽  
pp. 216-221 ◽  
Author(s):  
Suparna Chatterjee ◽  
Gur Prasad Dureja ◽  
Ganesh Kadhe ◽  
Amey Mane ◽  
Abhay A. Phansalkar ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Interim Report ◽  
Sectional Study ◽  
Drug Induced ◽  
Cross Sectional ◽  
Inflammatory Drug ◽  
Renal Complications ◽  
Anti Inflammatory

Non-Steroidal Anti-Inflammatory Drugs: Usage and Co-prescription with Other Potentially Interacting Drugs in Elderly: a Cross-sectional Study

2019 ◽  
Author(s):  
Nuru Abdu ◽  
Samuel Teweldemedhin ◽  
Asmerom Mosazghi ◽  
Luwam Asfaha ◽  
Makda Teshale ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Drug Interactions ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Protective Agents ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Abstract Introduction: Globally, non-steroidal anti-inflammatory drugs (NSAIDs) usage in the elderly with chronic pain has been reported as frequent. Though it is fundamental in maintaining their quality of life, the risk of polypharmacy, drug interactions and adverse effects is of paramount importance as the elderly usually require multiple medications for their co-morbidities. If prescriptions are not appropriately monitored and managed, they are likely to expose patients to serious drug interactions and potentially fatal adverse effects. Thus, the objective of the study was to assess the appropriateness of NSAIDs use and incidence of NSAIDs related potential interactions in elderly. Methods: A descriptive cross-sectional study was conducted among elderly out-patients (aged 60 and above) who visited three hospitals in Asmara between August 22 and September 29, 2018. The sampling design was two-stage random sampling and data was collected using a questionnaire, exit interview and by abstracting information from patients’ clinical cards. Descriptive and analytical statistics including chi-square test and logistic regression were employed using SPSS. Results: A total of 285 elderly respondents were enrolled in the study with similar male to female ratio. One in four of all respondents were chronic NSAIDs users, of which 74.6% were not prescribed prophylactic gastro-protective agents (GPAs). About 20% of the elderly were involved in polypharmacy and nearly all of the encountered potential NSAIDs related interactions (n=322) with prescribed drugs were moderate. Diabetes and hypertension were significantly associated with chronic NSAIDs use (OR=3, 95% CI: 1.54, 5.84; OR=9.99, 95% CI: 4.46, 22.38) and incidence of drug interactions (OR=3.95, 95%CI: 1.92, 8.13; OR=3.12, 95%CI: 1.81, 5.33) while diabetes and cardiac problem were significantly associated with incidence of polypharmacy (OR=4.33, 95% CI: 2.36, 7.96; OR=3.56, 95% CI: 1.05, 12.11). Conclusion: Though the overall reflection of prescription pattern of NSAIDs during the study period was almost satisfactory, gastro-protective agents were poorly prescribed as a prophylaxis.

Relationship of the Inflammatory Diet Status and Dietary Intake with Antimalarial Treatment in Systemic Lupus Rrythematosus: A Cross-Sectional Study

2020 ◽  
Author(s):  
Mónica R. Meza-Meza ◽  
Nitin Shivappa ◽  
Margarita Montoya-Buelna ◽  
José Francisco Muñoz-Valle ◽  
James R. Hébert ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Total Cholesterol ◽  
Cross Sectional Study ◽  
Dietary Reference Intake ◽  
Sectional Study ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Inflammatory Status ◽  
Anti Inflammatory ◽  
Relationship Of

Abstract Background: Systemic lupus erythematosus (SLE) is the prototype autoimmune disease with high inflammatory cytokine levels. In autoimmune conditions, diet could modify the inflammatory status, comorbidities and pharmacotherapy administered in SLE patients. The aim of this study was to assess the relationship of the inflammatory diet status and dietary intake with comorbidities and pharmacotherapy administered in SLE patients. Methods: A cross-sectional study was conducted in sixty-eight Mexican-Mestizo female SLE patients. Dietary intake was estimated from three 24h food records by Nutritionist Pro-Diet software and 27 food parameters were used to evaluate the inflammatory diet status by the normal dietary inflammatory index (DII®). Results: SLE patients presented a global pro-inflammatory diet status (DII: 0.71 ± 1.78). Chloroquine (CQ) administration was related to a pro-inflammatory diet status compared to hydroxychloroquine (HCQ) administration, which was related to an anti-inflammatory diet status (CQ= DII score: 1.385±1.327 vs. HCQ= DII score: 0.004±2.024; p=0.002). CQ administration conferred a pro-inflammatory DII score (β coefficient= 1.20; CI: 1–2.02; R2=0.11; p<0.01) and lower total-cholesterol (β coefficient=-29.2; CI: -4.03 to -54.5; R2=0.07; p<0.05); conversely, HCQ administration conferred an anti-inflammatory DII score (β coefficient= -1.29; CI: -0.46 to -2.12; R2=0.13; p<0.01). SLE patients with CQ administration had lower intake of energy and 12 nutrients evaluated (CQ vs. HCQ; p <0.05), and SLE patients with HCQ treatment had a better achievement ≥100% of daily dietary reference intake (DRI) of energy (HCQ 77% vs. CQ 52%; p=0.03), vitamin A (HCQ 65% vs. CQ 29%; p<0.01), cholesterol (HCQ 29% vs. CQ 3%; p<0.01), and fiber (HCQ 26% vs. CQ 6%; p=0.03).Conclusions: In SLE patients the CQ administration was related to a pro-inflammatory diet status and low total-cholesterol, and HCQ administration with an anti-inflammatory diet status and better dietary intake.

National cross-sectional study of nonsteroidal anti-inflammatory drugs use highlights differences between parents and professionals and prompts safety concerns

2016 ◽  
Vol 105 (11) ◽  
pp. e543-e548 ◽  
Author(s):  
Nathalie Bertille ◽  
Gérard Pons ◽  
Elisabeth Fournier-Charrière ◽  
Babak Khoshnood ◽  
Martin Chalumeau
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Safety Concerns ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Analysis of interleukin-10 anti-inflammatory cytokines in salivary lymphocyte surface: A cross sectional study

2020 ◽  
Vol 12 (5) ◽  
pp. 439
Author(s):  
Muhammad Luthfi ◽  
Retno Indrawati ◽  
AqsaS Oki ◽  
Yuliati ◽  
Agung Sosiawan ◽  
...  
Keyword(s):  
Inflammatory Cytokines ◽  
Interleukin 10 ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lymphocyte Surface ◽  
Anti Inflammatory

scholarly journals The Misconception of Antibiotic Equal to an Anti-Inflammatory Drug Promoting Antibiotic Misuse among Chinese University Students

2019 ◽  
Vol 16 (3) ◽  
pp. 335 ◽  
Author(s):  
Weiyi Wang ◽  
Xiaomin Wang ◽  
Yanhong Jessika Hu ◽  
Dan Wu ◽  
Jingjing Lu ◽  
...  
Keyword(s):  
University Students ◽  
Rural Areas ◽  
Urban Areas ◽  
Cross Sectional Study ◽  
Self Medication ◽  
Chi Square ◽  
Cross Sectional ◽  
Inflammatory Drug ◽  
Chi Square Test ◽  
Anti Inflammatory

Massive misuse of antibiotics is one of the most important reasons for antimicrobial resistance (AMR). Misconceptions of antibiotics contribute to antibiotic misuse behaviors. This study aims to examine whether university students hold the misconception that Antibiotic is a Xiaoyanyao (literally means anti-inflammatory drug in Chinese), and association between this misconception and antibiotic misuse behaviors. A cross-sectional study was conducted among university students using the cluster random sampling method in six universities of six regions in China (one university per region). The Chi-square test was used to assess the relationship between the misconception and antibiotic misuse behaviors. Logistic regression was conducted to identify the risk factors for antibiotic misuse behaviors. 11,192 of university students completed the entire questionnaire. There were 3882 (34.7%) students who were considered to have the misconception. Female students were more likely to have the misconception compared with males (36.7% vs. 32.6%, P < 0.001). Those students with a background of social science/humanities were more likely to have the misconception compared with those from science and medicine (44.1% vs. 30.3% vs. 20.1%, P < 0.001). Students came from rural areas compared with those from urban areas (37.5% vs. 32.5%, P < 0.001) were more likely to have the misconception. Students who had the misconception were 1.51 (95% CI 1.21–1.89, P < 0.001) times, 1.34 (95% CI 1.21–1.48, P < 0.001) times, and 1.36 (95% CI 1.24–1.50, P < 0.001) times more likely to report self-medication, request to obtain antibiotics, and take antibiotics prophylactically than those who did not have this misconception, respectively. The high proportion of university students' misconception on Antibiotic is a Xiaoyanyao is worth more attention. Effective health education and interventions need to be promoted among university students and the whole population.

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