The rising incidence of eosinophilic oesophagitis is associated with increasing biopsy rates: a population-based study

2012 ◽  
Vol 36 (10) ◽  
pp. 950-958 ◽  
Author(s):  
A. A. N. Syed ◽  
C. N. Andrews ◽  
E. Shaffer ◽  
S. J. Urbanski ◽  
P. Beck ◽  
...  
2017 ◽  
Vol 45 (4) ◽  
pp. 574-579 ◽  
Author(s):  
Mohanad M. Elfishawi ◽  
Nour Zleik ◽  
Zoran Kvrgic ◽  
Clement J. Michet ◽  
Cynthia S. Crowson ◽  
...  

Objective.To examine the incidence of gout over the last 20 years and to evaluate possible changes in associated comorbid conditions.Methods.The medical records were reviewed of all adults with a diagnosis of incident gout in Olmsted County, Minnesota, USA, during 2 time periods (January 1, 1989–December 31, 1992, and January 1, 2009–December 31, 2010). Incident cases had to fulfill at least 1 of 3 criteria: the American Rheumatism Association 1977 preliminary criteria for gout, the Rome criteria, or the New York criteria.Results.A total of 158 patients with new-onset gout were identified during 1989–1992 and 271 patients during 2009–2010, yielding age- and sex-adjusted incidence rates of 66.6/100,000 (95% CI 55.9–77.4) in 1989–1992 and 136.7/100,000 (95% CI 120.4–153.1) in 2009–2010. The incidence rate ratio was 2.62 (95% CI 1.80–3.83). At the time of their first gout flare, patients diagnosed with gout in 2009–2010 had higher prevalence of comorbid conditions compared with 1989–1992, including hypertension (69% vs 54%), diabetes mellitus (25% vs 6%), renal disease (28% vs 11%), hyperlipidemia (61% vs 21%), and morbid obesity (body mass index ≥ 35 kg/m2; 29% vs 10%).Conclusion.The incidence of gout has more than doubled over the recent 20 years. This increase together with the more frequent occurrence of comorbid conditions and cardiovascular risk factors represents a significant public health challenge.


2008 ◽  
Vol 134 (4) ◽  
pp. A-291
Author(s):  
Chadwick I. Williams ◽  
Marc P. Dupre ◽  
Gilaad G. Kaplan ◽  
Christopher N. Andrews ◽  
Eldon A. Shaffer ◽  
...  

2021 ◽  
pp. 000313482110111
Author(s):  
Mercedes Pilkington ◽  
Arany Theivendram ◽  
Susan B. Brogly ◽  
Mila Kolar

Background Intussusception is the most common cause of bowel obstruction in children aged 3 months to 6 years of age. We sought to describe patterns of incident childhood intussusception. Methods A retrospective longitudinal cohort study utilizing population-based health administrative data and a validated case definition was used to identify patients <18 years of age treated for intussusception between January 1, 1997 and December 31, 2016 in Ontario, Canada. Descriptive statistics, graphical analyses, and a Poisson regression model were performed for trend analysis. Results The overall incidence of intussusception in Ontario children (<18 years) was 3.3 cases/100,000 child years (cyrs), 95% CI [3.2.3.5]. The overall incidence increased from .9 cases/100,000 cyrs to 2.3 cases/100,000 cyrs. The highest incidence was in children aged 6-12 months at 28.9 cases/100,000 cyrs, 95% CI [26.2.31.9]. Incidence increased in all age-groups between 6 months and 5 years (at a rate of 5% to 16% per year; all P < .05). Month of year did not predict intussusception counts in a log-linear Poisson models, nor did rotavirus immunization implementation in 2011. There was a 3-fold variability across geographic areas in the province. There was a high rate of readmission for recurrence within 1 year (10.7%). Conclusion The incidence of intussusception more than doubled in Ontario from 1997 to 2016. The incidence increased for children aged between 6 months and 5 years at a rate of 5-16% per year, suggesting that an increased rate of idiopathic intussusception is responsible for the increase in the province.


2014 ◽  
Vol 16 (7) ◽  
pp. O234-O239 ◽  
Author(s):  
J. R. Wilkinson ◽  
E. J. A. Morris ◽  
A. Downing ◽  
P. J. Finan ◽  
A. Aravani ◽  
...  

2014 ◽  
Vol 34 (6) ◽  
pp. e31-e38 ◽  
Author(s):  
Kirsten Boonstra ◽  
Anton E. Kunst ◽  
Paul H. Stadhouders ◽  
Hans A. Tuynman ◽  
Alexander C. Poen ◽  
...  

1996 ◽  
Vol 6 (4) ◽  
pp. 309-312 ◽  
Author(s):  
D.T. McConnell ◽  
B.J. Wilson ◽  
D. Russell ◽  
D.E. Parkin ◽  
H.C. Kitchener

2006 ◽  
Vol 259 (4) ◽  
pp. 410-417 ◽  
Author(s):  
R. W. THOMSEN ◽  
A. RIIS ◽  
M. NORGAARD ◽  
J. JACOBSEN ◽  
S. CHRISTENSEN ◽  
...  

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