Incidence and prevalence of eosinophilic oesophagitis increase continiously in adults and children in Central Spain: A 12-year population-based study

2019 ◽  
Vol 51 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Ángel Arias ◽  
Alfredo J. Lucendo
Author(s):  
Gloria B. Roldán Urgoiti ◽  
Amitabh D. Singh ◽  
Roger Y. Tsang ◽  
Robert A. Nordal ◽  
Gerald Lim ◽  
...  

AbstractBackground: Ependymomas are rare tumors of the central nervous system whose management is controversial. This population-based study of adults and children with ependymoma aims to (1) identify clinical and treatment-related factors that impact survival and (2) determine if postoperative radiotherapy (RT) can improve survival of patients with subtotal resection (STR) to levels similar to patients who had gross total resection (GTR). Methods: This retrospective population-based study evaluated 158 patients with ependymoma diagnosed between 1975-2007 in Alberta, Canada. Results: Younger patients (<7 years of age) were more likely to be diagnosed with grade III tumors compared with adults in whom grade I tumors were more common (p=0.003). Adults were more likely to have spinally located tumors compared to young children whose tumors were typically found in the brain. Overall, young children with ependymoma were more likely to die than older children or adults (p=0.001). An equivalent number of patients underwent GTR as compared with STR (48% vs 45%, respectively). Overall, older age, spinal tumor location, lower grade, and GTR were associated with improved progression free survival but only GTR was associated with significant improvement in overall survival. Median survival after STR and RT was 82 months compared with 122 months in patients who had GTR (p=0.0022). Conclusions: This is the first Canadian population-based analysis of patients with ependymoma including adults and children. Extent of resection appears to be the most important factor determining overall survival. Importantly, the addition of RT to patients initially treated with STR does not improve survival to levels similar to patients receiving GTR.


2013 ◽  
Vol 163 (1) ◽  
pp. 217-223.e3 ◽  
Author(s):  
Esther Cubo ◽  
José Trejo ◽  
Vanesa Ausín ◽  
Sara Sáez ◽  
Vanesa Delgado ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e027700 ◽  
Author(s):  
Luise Lago ◽  
Victoria Westley-Wise ◽  
Judy Mullan ◽  
Kelly Lambert ◽  
Rebekah Zingel ◽  
...  

ObjectivesPatients are presenting to emergency departments (EDs) with increasing complexity at rates beyond population growth and ageing. Intervention studies target patients with 12 months or less of frequent attendance. However, these interventions are not well targeted since most patients do not remain frequent attenders. This paper quantifies temporary and ongoing frequent attendance and contrasts risk factors for each group.DesignRetrospective population-based study using 10 years of longitudinal data.SettingAn Australian geographic region that includes metropolitan and rural EDs.Participants332 100 residents visited any ED during the study period.Main outcome measureFrequent attendance was defined as seven or more visits to any ED in the region within a 12-month period. Temporary frequent attendance was defined as meeting this threshold only once, and ongoing more than once. Risk factors for temporary and ongoing frequent attenders were identified using logistic regression models for adults and children.ResultsOf 8577 frequent attenders, 80.1% were temporary and 19.9% ongoing (12.9% repeat, 7.1% persistent). Among adults, ongoing were more likely than temporary frequent attenders to be young to middle aged (aged 25–64 years), and less likely to be from a high socioeconomic area or be admitted. Ongoing frequent attenders had higher rates of non-injury presentations, in particular substance-related (OR=2.5, 99% CI 1.1 to 5.6) and psychiatric illness (OR=2.9, 99% CI 1.8 to 4.6). In comparison, children who were ongoing were more likely than temporary frequent attenders to be aged 5–15 years, and were not more likely to be admitted (OR=2.7, 99% CI 0.7 to 10.9).ConclusionsFuture intervention studies should distinguish between temporary and ongoing frequent attenders, develop specific interventions for each group and include rigorous evaluation.


2011 ◽  
Vol 45 (2) ◽  
pp. 100-108 ◽  
Author(s):  
Esther Cubo ◽  
José María Trejo Gabriel y Galán ◽  
Vanesa Ausín Villaverde ◽  
Sara Sáez Velasco ◽  
Vanesa Delgado Benito ◽  
...  

2012 ◽  
Vol 36 (10) ◽  
pp. 950-958 ◽  
Author(s):  
A. A. N. Syed ◽  
C. N. Andrews ◽  
E. Shaffer ◽  
S. J. Urbanski ◽  
P. Beck ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A628-A628
Author(s):  
E LOFTUSJR ◽  
C CROWSON ◽  
W SANDBORN ◽  
W TREAMINE ◽  
W OFALLON ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 73-73 ◽  
Author(s):  
Daniel A. Barocas ◽  
Farhang Rabbani ◽  
Douglas S. Scherr ◽  
E. Darracott Vaughan

2005 ◽  
Vol 173 (4S) ◽  
pp. 401-401
Author(s):  
Javier Hernandez ◽  
Jacques Baillargeon ◽  
Brad Pollock ◽  
Alan R. Kristal ◽  
Patrick Bradshaw ◽  
...  

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