scholarly journals Despite poor interferon response in advanced hepatitis C virus infection, models of protease inhibitor treatment predict maximum treatment benefit

2012 ◽  
Vol 36 (7) ◽  
pp. 670-679 ◽  
Author(s):  
I. A. Rowe ◽  
D. D. Houlihan ◽  
D. J. Mutimer
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Interferon Response ◽  
Hepatitis C Virus Infection ◽  
Treatment Benefit ◽  
Infection Models ◽  
Inhibitor Treatment

Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

2020 ◽  
Vol 63 (23) ◽  
pp. 14740-14760
Author(s):  
Li-Qiang Sun ◽  
Eric Mull ◽  
Stanley D’Andrea ◽  
Barbara Zheng ◽  
Sheldon Hiebert ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Third Generation ◽  
Hepatitis C Virus Infection

Modelling how ribavirin improves interferon response rates in hepatitis C virus infection

Nature ◽  
2004 ◽  
Vol 432 (7019) ◽  
pp. 922-924 ◽  
Author(s):  
Narendra M. Dixit ◽  
Jennifer E. Layden-Almer ◽  
Thomas J. Layden ◽  
Alan S. Perelson
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Response Rates ◽  
Interferon Response ◽  
Hepatitis C Virus Infection

scholarly journals Hepatitis C Virus Infection Suppresses the Interferon Response in the Liver of the Human Hepatocyte Chimeric Mouse

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23856 ◽  
Author(s):  
Masataka Tsuge ◽  
Yoshifumi Fujimoto ◽  
Nobuhiko Hiraga ◽  
Yizhou Zhang ◽  
Mayu Ohnishi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Human Hepatocyte ◽  
Interferon Response ◽  
Chimeric Mouse ◽  
Hepatitis C Virus Infection

MK-5172: a second-generation protease inhibitor for the treatment of hepatitis C virus infection

2014 ◽  
Vol 23 (5) ◽  
pp. 719-728 ◽  
Author(s):  
Ivan Gentile ◽  
Antonio Riccardo Buonomo ◽  
Federico Borgia ◽  
Emanuela Zappulo ◽  
Giuseppe Castaldo ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Second Generation ◽  
Hepatitis C Virus Infection

scholarly journals Analysis of Hepatitis C Virus Infection Models with Hepatocyte Homeostasis

2009 ◽  
Vol 69 (4) ◽  
pp. 999-1023 ◽  
Author(s):  
Timothy C. Reluga ◽  
Harel Dahari ◽  
Alan S. Perelson
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Infection Models
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