Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

2014 ◽  
Vol 57 (5) ◽  
pp. 1708-1729 ◽  
Author(s):  
Paul M. Scola ◽  
Alan Xiangdong Wang ◽  
Andrew C. Good ◽  
Li-Qiang Sun ◽  
Keith D. Combrink ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Clinical Evaluation ◽  
Hepatitis C Virus Infection ◽  
Ns3 Protease

The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

2014 ◽  
Vol 57 (5) ◽  
pp. 1730-1752 ◽  
Author(s):  
Paul M. Scola ◽  
Li-Qiang Sun ◽  
Alan Xiangdong Wang ◽  
Jie Chen ◽  
Ny Sin ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Hepatitis C Virus Infection ◽  
Ns3 Protease

Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

2020 ◽  
Vol 63 (23) ◽  
pp. 14740-14760
Author(s):  
Li-Qiang Sun ◽  
Eric Mull ◽  
Stanley D’Andrea ◽  
Barbara Zheng ◽  
Sheldon Hiebert ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Third Generation ◽  
Hepatitis C Virus Infection

Macrocyclic Inhibitors of the NS3 Protease as Potential Therapeutic Agents of Hepatitis C Virus Infection

2003 ◽  
Vol 42 (12) ◽  
pp. 1356-1360 ◽  
Author(s):  
Youla S. Tsantrizos ◽  
Gordon Bolger ◽  
Pierre Bonneau ◽  
Dale R. Cameron ◽  
Nathalie Goudreau ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Therapeutic Agents ◽  
Hepatitis C Virus Infection ◽  
Ns3 Protease

MK-5172: a second-generation protease inhibitor for the treatment of hepatitis C virus infection

2014 ◽  
Vol 23 (5) ◽  
pp. 719-728 ◽  
Author(s):  
Ivan Gentile ◽  
Antonio Riccardo Buonomo ◽  
Federico Borgia ◽  
Emanuela Zappulo ◽  
Giuseppe Castaldo ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Protease Inhibitor ◽  
Second Generation ◽  
Hepatitis C Virus Infection
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