Prevention of duodenal ileus reveals functional differences in the duodenal response to luminal hypertonicity in Sprague-Dawley and Dark Agouti rats

2013 ◽  
Vol 210 (3) ◽  
pp. 573-589 ◽  
Author(s):  
J. Sedin ◽  
M. Sjöblom ◽  
O. Nylander
Keyword(s):  
Dark Agouti ◽  
Sprague Dawley ◽  
Functional Differences ◽  
Duodenal Ileus

scholarly journals DIFFERENCES IN ADRENAL MORPHOLOGY IN MALE DARK AGOUTI, SPRAGUE-DAWLEY AND WISTAR RATS

1999 ◽  
Vol 47 (3) ◽  
pp. 335-339 ◽  
Author(s):  
Jenny M. Wilkinson ◽  
S. Halley ◽  
P. A. Towers
Keyword(s):  
Wistar Rats ◽  
Adrenal Glands ◽  
Volume Fraction ◽  
Single Species ◽  
The Other ◽  
Dark Agouti ◽  
Sprague Dawley ◽  
Zona Reticularis ◽  
Functional Differences ◽  
Morphological Differences

There is little published information describing the differences in adrenal structure between strains of a single species despite quite well known functional differences. In this paper we report morphological differences in the adrenal glands between three strains of laboratory rat; Dark Agouti (DA), Sprague-Dawley (SD) and Wistar (W). Significant differences in adrenal weights (as a percentage of body weight) were not detected between any of the groups. While there were no significant differences in the volume of medullary or zonae glomerulosa or fasciculata tissue, the volume fraction for the zona reticularis was significantly smaller in DAs compared to the other strains. The functional significance of these differences is unknown. However, it is suggested that the reduced volume of zona reticularis tissue may contribute to a reduced capacity for glucocorticoid synthesis or storage.

Dextrorotatory opioids induce stereotyped behavior in Sprague-Dawley and Dark Agouti rats

1998 ◽  
Vol 140 (2) ◽  
pp. 206-216 ◽  
Author(s):  
J. E. Ishmael ◽  
P. H. Franklin ◽  
T. F. Murray
Keyword(s):  
Stereotyped Behavior ◽  
Dark Agouti ◽  
Sprague Dawley

Comparison of CYP2D metabolism and hepatotoxicity of the myocardial metabolic agent perhexiline in Sprague–Dawley and Dark Agouti rats

Xenobiotica ◽  
2014 ◽  
Vol 45 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Giovanni Licari ◽  
Andrew A. Somogyi ◽  
Robert W. Milne ◽  
Benedetta C. Sallustio
Keyword(s):  
Dark Agouti ◽  
Sprague Dawley

Sodium chloride preference of genetically hypertensive and normotensive rats

1983 ◽  
Vol 245 (1) ◽  
pp. R38-R44 ◽  
Author(s):  
R. Di Nicolantonio ◽  
F. A. Mendelsohn ◽  
J. S. Hutchinson
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rat ◽  
Sodium Intake ◽  
Bb Rat ◽  
Dark Agouti ◽  
Sprague Dawley ◽  
Saline Preference ◽  
Wistar Kyoto ◽  
Preference Tests ◽  
Genetically Hypertensive

Preference for 0.9% saline was examined, using two-bottle preference tests over 6-7 days, in the spontaneously hypertensive rat (SHR) and normotensive Wistar Kyoto rat (WK) of the Okamoto strain, the genetically hypertensive (GHR) and normotensive rat (NT) of the Smirk strain, and the Sprague-Dawley (SD), Dark Agouti (DA), and hooded Long-Evans or Brattleboro (BB) rat. Only the SHR exhibited a sustained and marked preference for 0.9% saline on each test day. The WK, GHR, NT, and SD preferred saline in the first 24-48 h of testing but thereafter showed neither a preference for, nor aversion to, saline. The BB showed neither a preference for, nor aversion to, saline in the first 24 h of testing and thereafter showed a significant aversion to saline on each test day. Saline preference was further examined in both the SHR and WK offered a choice of water and 0.9%, 2.0, or 2.7% saline. While preference for saline decreased in both SHR and WK with increasing saline concentration, the SHR maintained a significantly greater preference for saline and greater total sodium intake than the WK at each concentration. Hydralazine (5 mg . kg-1 . day-1, po) administered to SHR, while they were offered a choice of water and 0.9% saline, significantly lowered blood pressure over a 4-day period but failed to alter their saline preference significantly. We conclude that of the seven strains of rats examined only the SHR exhibited a preference for saline in extended two-bottle preference tests. Furthermore this preference for saline appears to be maintained independently of the blood pressure of the SHR.

Acute Toxicity of 3,4-Methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti Rats

1999 ◽  
Vol 64 (1) ◽  
pp. 29-34 ◽  
Author(s):  
A Malpass ◽  
J.M White ◽  
R.J Irvine ◽  
A.A Somogyi ◽  
F Bochner
Keyword(s):  
Acute Toxicity ◽  
Dark Agouti ◽  
Sprague Dawley
Sign in / Sign up

Export Citation Format

Share Document