Finnish children who experienced narcolepsy after receiving the Pandemrix vaccine during the 2009‐2010 H1N1 pandemic demonstrated high level of psychosocial problems

2021 ◽  
Author(s):  
Marita Hovi ◽  
Hannu Heiskala ◽  
Eeva T. Aronen ◽  
Outi Saarenpää‐Heikkilä ◽  
Päivi Olsen ◽  
...  
Keyword(s):  
Psychosocial Problems ◽  
H1n1 Pandemic ◽  
High Level

scholarly journals Assessment of the Psycho Social Problems Related with Obese Juveniles in Actual Government School at Chennai

2021 ◽  
pp. 125-146
Author(s):  
A. R. Bharathi
Keyword(s):  
Social Problems ◽  
Nuclear Family ◽  
Demographic Data ◽  
Health Belief ◽  
Psychosocial Problems ◽  
Structured Interview ◽  
Government School ◽  
Obese Adolescents ◽  
Belief Theory ◽  
High Level

To evaluate the level of obesity, associated psychosocial problems and comparison with demographic variables in a selected government school at Chennai. Stock (1974) health belief Theory, a non-experimental study design, was used as the conceptual frame work in the present study. The students were randomly selected for the study Semi structured interview questions and questionnaire were used to assess the psychosocial problems of adolescents and demographic data of the students, respectively. The results revealed that psycho social problems were found among 50 obese adolescents, majority of them are 15-18 years of age, females, nuclear family, Hindus and non-vegetarian. It was also exclusively observed that obese adolescents had high level of psycho social problems.

scholarly journals A Study on Satisfaction Levels among Hearing Aid Users in Gangetic Plains

2021 ◽  
Vol 28 (3) ◽  
pp. 203-208
Author(s):  
Bipin Kishore Prasad ◽  
Abhijit Basu ◽  
Ajay Kumar Rai
Keyword(s):  
Hearing Aids ◽  
Hearing Aid ◽  
Family Members ◽  
Psychosocial Problems ◽  
Outcome Analysis ◽  
Satisfaction Level ◽  
Gangetic Plains ◽  
Level Of Satisfaction ◽  
Severe Degree ◽  
High Level

Introduction Outcome assessments have emerged as an effective method for determining whether or not hearing aids are working to achieve positive results in rehabilitating the hearing impaired. Present study aims to assess the satisfaction level of clientele using hearing aids.                   Material and Methods One hundred and fourteen (114) hearing handicapped patients, fitted with government-provided hearing aids at various clinics spread over Gangetic plains were included in this prospective observational study for outcome analysis. Follow up was done at 2 weeks and 45 days when they were further motivated to continue using the aid, comfortable fitting of mould was ensured along with minor trouble shooting. Four and half months later, their satisfaction level was assessed by analysing their response to Clientele Satisfaction Questionnaire.   Results Fifty percent of the patients were motivated by their family members to try the aid whereas 50% were self motivated. Better communication with family members and immediate social circle was the common motive. Majority (85%) reported high level of satisfaction in terms of hearing benefit. Patients with severe degree of hearing loss were more satisfied and used the aid for longer duration in a day. Handling the aid was not as much of a problem as tolerating the noise produced by aid itself. Cost of battery was a concern for 80% of our clientele.   Conclusion Proper fitting of hearing aid improved the quality of life of majority of our hearing handicapped clientele by overcoming their psychosocial problems.

scholarly journals Psychosocial problems of schoolchildren and the psychological counseling approaches implicated by counselors for treating it

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Mohammad Qassim Abdullah
Keyword(s):  
Behavioral Problems ◽  
Group Counseling ◽  
Basic Education ◽  
Psychosocial Problems ◽  
Validity And Reliability ◽  
Rational Emotive Therapy ◽  
Psychological Counseling ◽  
Academic Qualification ◽  
Client Centered Therapy ◽  
High Level

The aim of this study was to examine and evaluate the behavioral problems of schoolchildren in basic education stage and the psychological counseling approaches implicated by their counselor for treating it. In addition, assessing the differences in these approaches according to the variables of gender and educational qualification/degree. The sample consisted of (240) counselors (125 male, 115 female) enrolled from five educational administrations. The procedure has been used concluded Scale constructed for assessing the behavioral problems students and psychological counseling approaches used by counselors. The instrument's characteristics scored high level of validity and reliability. The findings showed that the most common behavioral problems were disobedience of teachers underachievement, aggression. In addition,  the most counseling approaches used by counselors were individual and group counseling,  Leisure time counseling, rational-emotive therapy, plying counseling, reality therapy, and client-centered therapy. According to the differences in counseling approaches relating to gender and academic qualification or degree of counselors, there were no significant differences except for the approaches of cognitive, behavioral and group counseling techniques and approaches.

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

Advances in Stem Instrumentation for Biology

1990 ◽  
Vol 48 (1) ◽  
pp. 362-363
Author(s):  
J. S. Wall
Keyword(s):  
Scanning Transmission Electron Microscope ◽  
Carbon Films ◽  
Specimen Preparation ◽  
Material Deposition ◽  
Active User ◽  
Percent Improvement ◽  
Scanning Transmission ◽  
The Moment ◽  
Film Substrate ◽  
High Level

The forte of the Scanning transmission Electron Microscope (STEM) is high resolution imaging with high contrast on thin specimens, as demonstrated by visualization of single heavy atoms. of equal importance for biology is the efficient utilization of all available signals, permitting low dose imaging of unstained single molecules such as DNA.Our work at Brookhaven has concentrated on: 1) design and construction of instruments optimized for a narrow range of biological applications and 2) use of such instruments in a very active user/collaborator program. Therefore our program is highly interactive with a strong emphasis on producing results which are interpretable with a high level of confidence.The major challenge we face at the moment is specimen preparation. The resolution of the STEM is better than 2.5 A, but measurements of resolution vs. dose level off at a resolution of 20 A at a dose of 10 el/A2 on a well-behaved biological specimen such as TMV (tobacco mosaic virus). To track down this problem we are examining all aspects of specimen preparation: purification of biological material, deposition on the thin film substrate, washing, fast freezing and freeze drying. As we attempt to improve our equipment/technique, we use image analysis of TMV internal controls included in all STEM samples as a monitor sensitive enough to detect even a few percent improvement. For delicate specimens, carbon films can be very harsh-leading to disruption of the sample. Therefore we are developing conducting polymer films as alternative substrates, as described elsewhere in these Proceedings. For specimen preparation studies, we have identified (from our user/collaborator program ) a variety of “canary” specimens, each uniquely sensitive to one particular aspect of sample preparation, so we can attempt to separate the variables involved.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

Severe Drooling and Treatment With Botulinum Toxin

2012 ◽  
Vol 21 (1) ◽  
pp. 15-21
Author(s):  
Merete Bakke ◽  
Allan Bardow ◽  
Eigild Møller
Keyword(s):  
Botulinum Toxin ◽  
Side Effects ◽  
Health Risk ◽  
Flow Rate ◽  
Clinical Evidence ◽  
Acetylcholine Release ◽  
Psychosocial Problems ◽  
Rate Reduction ◽  
Local Inhibition ◽  
Surgical Treatments

Severe drooling is associated with discomfort and psychosocial problems and may constitute a health risk. A variety of different surgical and non-surgical treatments have been used to diminish drooling, some of them with little or uncertain effect and others more effective but irreversible or with side effects. Based on clinical evidence, injection with botulinum toxin (BTX) into the parotid and submandibular glands is a useful treatment option, because it is local, reversible, and with few side effects, although it has to be repeated. The mechanism of BTX is a local inhibition of acetylcholine release, which diminishes receptor-coupled secretion and results in a flow rate reduction of 25–50% for 2–7 months.

805: High-Level Cyclin D1 is Associated with High Gleason Grade and Predicts Worse Biochemical-Free Survival in Prostate Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Rile Li ◽  
Hong Dai ◽  
Thomas M. Wheeler ◽  
Anna Frolov ◽  
Gustavo Ayala
Keyword(s):  
Prostate Cancer ◽  
Cyclin D1 ◽  
Gleason Grade ◽  
Free Survival ◽  
High Level
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