Mortality and Morbidity in Preterm Infants with Congenital Heart Disease

2021 ◽  
Author(s):  
Ioana Dumitrascu Biris ◽  
Alison Mintoft ◽  
Christopher Harris ◽  
Rawn Zeshan ◽  
Jatinder Singh Jheeta ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Preterm Infants ◽  
Congenital Heart ◽  
Mortality And Morbidity

Incidence, pattern and presentation of Congenital Heart Disease in neonates in southern part of Bangladesh

Mediscope ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 27-32
Author(s):  
Md Barkot Ali ◽  
Syed Didarul Haque ◽  
Amar Kumar Saha ◽  
Faruquzzaman ◽  
Muhammad Ashraful Kabir ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Live Birth ◽  
Congenital Heart ◽  
Average Weight ◽  
Mortality And Morbidity ◽  
Co Morbidity ◽  
Age Of Diagnosis ◽  
Common Clinical Presentation ◽  
High Index Of Suspicion

Background: Congenital heart disease (CHD) has already been recognized as one of the important cause of neonatal mortality and morbidity. The reported prevalence of CHD in live newborns tends to vary a lot due to various unrecognizable lesions at birth and lack of technical expertise. Aims & objectives: The ultimate aim of this study was to assess the birth incidence and pattern of congenital heart disease (CHD) using echocardiography in babies born in different government and private hospitals and also in different households. Results: Overall incidence of congenital heart disease in neonate in this study was 4.9 per 1000 live birth. Mean age of diagnosis was 22.5±4.6 days. Average weight of these neonates was 26.70 gm. 61.5 % neonates were female. 30.8% was preterm. Respiratory distress was the most common clinical presentation (76.9%). The commonest type of congenital heart disease was Ventricular septal defect (VSD) (61.5%). Maternal co-morbidity may have influence. 30.8% mothers had gestational diabetes mellitus. Hypothyroidism, hypertension and maternal infection may have co-relation. Conclusion: In this study, we have found that the overall incidence of neonatal congenital heart disease is 4.9 per 1000 live birth. A high index of suspicion and routine neonatal cheek-up may have key role in diagnosis. Mediscope Vol. 8, No. 1: January 2021, Page 27-32

P4697Complications and mortality related to non-cardiac surgery in adult congenital heart disease: Results of a nationwide study including 20,450 cases

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G P Diller ◽  
E Freisinger ◽  
L Bronstein ◽  
J Koeppe ◽  
J Gerss ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Adverse Event ◽  
Heart Disease ◽  
Surgical Procedures ◽  
Congenital Heart ◽  
Cardiac Surgical Procedures ◽  
Mortality Rates ◽  
Adverse Event Rate ◽  
Major Adverse Event ◽  
Mortality And Morbidity

Abstract Background Adults with congenital heart disease (ACHD) represent a growing patient population with high morbidity and increasing health resource utilization. In addition to acute and chronic cardiac complications, these patients require numerous non-cardiac surgical procedures during their life-time. Limited data on the morbidity and mortality risk related to non-cardiac surgical procedures exist in contemporary CHD patients. The aim of this study was to analyse the frequency and outcome of non-cardiac surgical procedures in contemporary ACHD patients based on all hospital admissions in Germany between 2011 and 2016. Methods Based on the German diagnosis related groups data of patients treated between 2011 and 2016 we identified all ACHD patients treated surgically as inpatients for non-cardiac problems. The dataset contains information on patient demographics, primary and secondary diagnoses, interventional or surgical procedures, duration of stay and outcome including mortality. The primary endpoint of the study was surgery related mortality as well as major adverse events (defined as death or myocardial infarction, stroke, pulmonary embolism, sepsis or resuscitation). Results Overall, 48,872 ACHD cases were hospitalized during the study period. Of these, 20,450 (41.8%) were hospitalized for non-cardiac surgical procedures. The median age at surgery was 50.0 years and 62.9% of patients were male. The overall mortality rate following non-cardiac operations was 2.8% (95% CI 2.6–3.0%). The highest mortality rates were observed for procedure codes involving pharynx, larynx or trachea (27.2%; 95% CI: 22.3–32.1%) and lung surgery (15.4%; 95% CI: 13.3–17.8%). Abdominal surgery (9.2%; 95% CI: 7.7–10.9) and neurosurgical procedures (7.8%; 95% CI: 5.4–10.9) also had relative high mortality rates. The major adverse event rate overall was 12.7% (95% CI 11.7–12.7%). The highest major adverse event rates were observed for surgery of the airways (43.2%; 95% CI: 40.2%-46.4%). Conclusions Non-cardiac surgical procedures are common in ACHD patients and are associated with considerable mortality and morbidity in this cohort. Especially, surgical procedures involving the airways or neurosurgery emerged as risky procedures. However, even for routine abdominal or orthopaedic surgery considerable mortality and morbidity was observed. Overall, our data support careful pre-operative patient evaluation and concentration of surgical procedures at centres with extensive surgical and anaesthetic experience with ACHD patients.

Outcome of preterm infants with congenital heart disease

2000 ◽  
Vol 137 (5) ◽  
pp. 653-659 ◽  
Author(s):  
Ellen Dees ◽  
Hwei Lin ◽  
Robert B. Cotton ◽  
Thomas P. Graham ◽  
Debra A. Dodd
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Preterm Infants ◽  
Congenital Heart

P1802Management and outcomes of infective endocarditis in adults with congenital heart disease

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
R Ly ◽  
D Lebeaux ◽  
F Pontnau ◽  
F Compain ◽  
B Gaye ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Infective Endocarditis ◽  
Congenital Heart ◽  
Hospital Death ◽  
Oral Streptococci ◽  
Mortality And Morbidity ◽  
Risk Of Death ◽  
Duke Criteria ◽  
Increased Risk

Abstract Background Causes, epidemiology and microbiology of infective endocarditis (IE) have evolved in recent decades. Although novel tools for the diagnosis and therapeutic strategies have emerged, mortality and morbidity remain high. These trends may particularly concern the growing population of adults with congenital heart disease (CHD) who are at increased risk for IE. Purpose We aimed to characterize IE in CHD patients and describe management and outcome in this setting. We also sought to determine the risk factors associated with in-hospital death in CHD patients. Methods From January 2000 to June 2018, 666 consecutive episodes of IE in adults were recorded in our center. Among them, 143 concerned CHD, including 5 implantable cardiac electronic devices-lead infections, all managed by an IE team including CHD specialists. Cases were classified according to modified Duke criteria. Results CHD patients were significantly younger (37 years IQR [26–52]), with a more common history of cardiac reoperations (numbers of sternotomies≥2 in 35.7%) and infective endocarditis (19.7%, p<0.01) compared to non-CHD patients. There were more infections of valve-containing prosthetics (44% vs. 30%, p<0.04), and the right heart side (41.5%, p<0.01) in CHD patients. Forty-nine percent of them had a simple CHD, 12.7% a moderate, and 36.4% a complex. A predisposing event could be identified in only 34% of cases. Oral streptococci/Streptococci bovis and Staphylococcus aureus were the most frequently microorganisms isolated (32.4% and 20.4%, respectively). Surgery was performed in 90 episodes (62%), and was selected in emergency (<24h) in 61% (figure 1). In-hospital mortality was 12.7% and was directly related to IE in 10/18 cases. CHD patients had a significant lower risk of death compared to non-CHD patients (OR=0.47, p=0.026, p<0.01), even after adjustment for age, and the infected heart side. On multivariate analysis the complexity of CHD (if simple CHD: OR=0.07 IQR [0.01 to 0.44], p<0.01) and the white blood cell count (OR=1.18 IQR [1.04 to 1.33], p=0.01) were the strongest predictive factors of in-hospital death in the CHD group. Conclusions Mortality associated with IE in CHD patients is lower than in acquired heart disease. The multidisciplinary approach by IE team and CHD specialists may have improved management and outcome in this setting. However, risk for death remains high in complex lesions. Larger prospective studies on IE in adults with CHD are needed to develop guidelines in these complex patients.

scholarly journals Pattern of Congenital Heart Disease in Children Presenting at Paediatric Cardiology Unit in Chattagram Maa Shishu-O-General Hospital, Chittagong

2018 ◽  
Vol 16 (2) ◽  
pp. 40-43
Author(s):  
Sukhendu Shekhar Sen ◽  
Tanuka Barua ◽  
Dipika Dey ◽  
Mahmood A Chowdhury ◽  
Lutfan Nessa
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Early Detection ◽  
Congenital Heart ◽  
Septal Defect ◽  
Color Doppler ◽  
Mortality And Morbidity ◽  
Diagnostic Facility ◽  
Disease Pattern ◽  
Acyanotic Congenital Heart Disease

Background: Congenital Heart Disease (CHD) is the most common congenital problem in children. Early detection and proper management of congenital heart disease is very important to reduce mortality and morbidity. The purpose of this study was to find out the disease pattern of CHD among children in present situation in a center outside Dhaka.Methods: This study was conducted over a period from March 2016 to June 2017 prospectively and all patients with CHD was diagnosed by Color Doppler Echocardiography aging from 1st day of life to 12 years were included in the study.Results: Acyanotic CHD was most common among CHD. Atrial Septal Defect (ASD) was the commonest acyanotic congenital heart disease 100 (35.7 %) followed by Ventricular Septal Defect (VSD) 77 (27.5 %). Commonest cyanotic CHD was Tetralogy of Fallot (TOF) 9 (3.2 %). Only 25.36 % CHD were diagnosed during neonatal period whereas 54.64 % were diagnosed during the period of 29 days to completion of 12 months. Most of the patient (63.21%) were male.Conclusion: ASD was the commonest acyanotic CHD whereas TOF was the commonest cyanotic CHD. About 80% cases were diagnosed before 1 year of age. With the advancement of diagnostic facility and neonatal care, early detection of CHD is possible and treatment can be started at an earlier age.Chatt Maa Shi Hosp Med Coll J; Vol.16 (2); July 2017; Page 40-43

Prevalence and Outcomes of Congenital Heart Disease in Very Low Birth Weight Preterm Infants

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Daniela Anderson ◽  
Davi Casale Aragon ◽  
Walusa A. Gonçalves-Ferri ◽  
Paulo H. Manso ◽  
Gabriela Leal ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Congenital Heart ◽  
Very Low Birth Weight
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