scholarly journals Cost analysis showed that feeding preterm infants with donor human milk was significantly more expensive than mother’s milk or formula

2019 ◽  
Vol 109 (5) ◽  
pp. 959-966 ◽  
Author(s):  
Josefine Fengler ◽  
Matthias Heckmann ◽  
Anja Lange ◽  
Axel Kramer ◽  
Steffen Flessa
Keyword(s):  
Cost Analysis ◽  
Human Milk ◽  
Preterm Infants ◽  
Donor Human Milk ◽  
Mother's Milk ◽  
Mother’S Milk

Human-Milk Feeding after NICU Discharge

2009 ◽  
Vol 28 (6) ◽  
pp. 381-389 ◽  
Author(s):  
Barbara Wheeler
Keyword(s):  
Human Milk ◽  
Preterm Infants ◽  
Infant Health ◽  
Outcome Variable ◽  
Canadian City ◽  
Mother's Milk ◽  
Main Outcome Variable ◽  
Mother’S Milk ◽  
To Receive ◽  
Milk Feeding

Purpose:Difficulty with breastfeeding is common, and challenges are particularly pronounced for mothers of ill or preterm infants. This study explores the breastfeeding experiences of mothers of these at-risk infants to determine their breastfeeding patterns and to better understand reasons they prematurely stop breastfeeding and/or human-milk feeding (HMF).Design:A qualitative, longitudinal, descriptive design was used.Sample:The sample consisted of 144 mothers whose preterm or ill infants were cared for in either an NICU or an intermediate care nursery in a large central Canadian city; 112 mothers completed data collection to six weeks after their infants were discharged from the hospital.Main Outcome Variable:The main outcome variable was continued breastfeeding or HMF of formerly ill or preterm infants at one and six weeks after their discharge from the hospital.Results:Of infants who were being fed mother’s milk when discharged from the hospital, 71 percent continued to receive at least some mother’s milk at six weeks after discharge. Mothers reported that their own physical and emotional problems, infant health concerns, and lack of time and support were reasons for discontinuing provision of human milk.

scholarly journals Milk Fat Globule Glycoproteins in Human Milk and in Gastric Aspirates of Mother's Milk-Fed Preterm Infants

1998 ◽  
Vol 44 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Jerry A Peterson ◽  
Margit Hamosh ◽  
Ciaran D Scallan ◽  
Roberto L Ceriani ◽  
Theresa R Henderson ◽  
...  
Keyword(s):  
Human Milk ◽  
Preterm Infants ◽  
Milk Fat ◽  
Milk Fat Globule ◽  
Mother's Milk ◽  
Fat Globule ◽  
Mother’S Milk

Implementation of the Reimbursement Cost of Human-Milk-Based Neonatal Therapy in Polish Health Care Service

2020 ◽  
Vol 36 (3) ◽  
pp. 426-435
Author(s):  
Aleksandra Wesolowska ◽  
Urszula Bernatowicz-Lojko ◽  
Elena Sinkiewicz-Darol ◽  
Beata Pawlus ◽  
Dominik Golicki
Keyword(s):  
Health Care ◽  
Human Milk ◽  
Care Service ◽  
Health Care Service ◽  
Tube Feeding ◽  
Nutritional Therapy ◽  
Donor Milk ◽  
Donor Human Milk ◽  
Mother's Milk ◽  
Mother’S Milk

Background A human-milk-based diet is the best option for nutritional therapy for preterm and/or sick newborns. Research aim The study aims were to restructure the reimbursement rates to hospitals in Poland for infants’ tube feedings to favor the use of donor human milk over formula for newborns who required supplementation of expressed mother’s milk and evaluate the results of the financing change during the first year of implementation (2018). Methods Financial data from hospitals were collected (2015–2016) by the Human Milk Bank Foundation using a data sheet designed by the Agency for Health Technology Assessment and Tariff System. We used data to restructure the reimbursement rates to hospitals for infants’ tube feedings and implemented the changes in late 2017. The National Health Fund was requested to share reported data in 2018 concerning tube feeding services. Results More than half (61%) of NICUs introduced human milk tube feeding for newborns. It was provided to participants ( N = 5,530), most frequently to seriously ill preterm infants (66.6%). Of these infants, 2,323 were fed donor human milk. Only 1,925 newborns received formula tube feeding. However, there were large differences in frequency of services reported among various parts of the country. Conclusions Based on our knowledge, Poland is the only European country where the reimbursement cost for human-milk-based nutritional therapy has been implemented in a manner intended to increase the quality of health care services for preterm newborns. Equal reimbursement for expressed mother’s milk and donor milk did not appear to cause overuse of donor milk based on our analysis of the 2018 data.

scholarly journals Growth Benefits of Own Mother’s Milk in Preterm Infants Fed Daily Individualized Fortified Human Milk

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 772 ◽  
Author(s):  
Virginie de Halleux ◽  
Catherine Pieltain ◽  
Thibault Senterre ◽  
Frédéric Studzinski ◽  
Catheline Kessen ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Human Milk ◽  
Preterm Infants ◽  
Premature Infants ◽  
Vlbw Infants ◽  
Beneficial Effects ◽  
Mother's Milk ◽  
Mother’S Milk ◽  
Gain Length ◽  
Length Gain

The influence of types of human milk (HM)—raw own mother’s milk (OMM), pasteurized OMM, and donor milk (DM)—was evaluated for growth in premature infants fed exclusively HM with controlled nutritional intakes using daily individualized HM fortification (IHMF). Growth and nutritional intakes were prospectively collected in preterm infants (<32 weeks) fed IHMF and compared in infants fed predominantly (≥75%) OMM and DM. The influence of HM types (raw OMM, pasteurized OMM, and DM) on growth were also evaluated in the whole population. One-hundred and one preterm infants (birth weight 970 ± 255 g, gestational age 27.8 ± 1.9 weeks) were included. Energy (143 ± 8 vs. 141 ± 6 kcal/kg/day; p = 0.15) and protein intakes (4.17 ± 0.15 vs. 4.15 ± 0.14 g/kg/day; p = 0.51) were similar in both groups. Infants receiving predominantly OMM (n = 37), gained significantly more weight (19.8 ± 2.0 vs. 18.2 ± 2.2 g/kg/day; p = 0.002) and length (1.17 ± 0.26 vs. 0.99 ± 0.36 cm/week; p = 0.020) than those fed predominantly DM (n = 33). Stepwise multivariate analysis (n = 101) suggests that raw OMM was the major determinant of growth, contributing 22.7% of weight gain. Length gain was also related to OMM (raw + pasteurized) intakes, explaining 4.0% of length gain. In conclusion, at daily controlled similar protein and energy intakes, OMM had significant beneficial effects on weight and length versus DM in VLBW infants. This difference could be partially explained by the use of raw OMM.

scholarly journals Pasteurized and unpasteurized donor human milk

2020 ◽  
Vol 25 (8) ◽  
pp. 549-549
Author(s):  
Catherine Pound ◽  
Sharon Unger ◽  
Becky Blair
Keyword(s):  
Human Milk ◽  
Health Care Providers ◽  
Care Providers ◽  
Donor Human Milk ◽  
Milk Bank ◽  
Wide Range ◽  
Mother's Milk ◽  
Mother’S Milk ◽  
Human Milk Bank ◽  
Alternative Feeding

Abstract It is universally accepted that human milk is the optimal, exclusive source of nutrition for infants 0 to 6 months of age, and may remain part of the healthy infant diet for the first 2 years of age and beyond. Despite advances in infant formulas, human milk provides a wide range of benefits, due in part to its bioactive matrix that cannot be replicated by any other source of nutrition. When there is an insufficient volume of mother’s milk for the vulnerable newborn, pasteurized donor human milk should be made available, as a bridge to mother’s milk and as the first alternative feeding choice, followed by commercial formula. There is a limited supply of donor milk in Canada and distribution is prioritized for sick, hospitalized neonates. Informal milk sharing is the practice of donating and receiving expressed human milk without going through a human milk bank. Informal milk sharing carries risk for bacterial and viral transmission as well as inconsistency and uncertainty regarding donor screening. Paediatricians and other health care providers need to be aware of the risks of informal milk sharing and be able to counsel families appropriately on safer alternatives.

scholarly journals Effects of kefir consumption on carbohydrate profile of mother’s milk

2021 ◽  
Vol 11 (9) ◽  
pp. 473
Author(s):  
Tuğçe Tok Kurt ◽  
Çağlar Gökırmaklı ◽  
Zeynep B Guzel-Seydim
Keyword(s):  
Immune System ◽  
Human Milk ◽  
Control Group ◽  
Birth Mothers ◽  
Pathogenic Organism ◽  
Liquid Chromatographic Method ◽  
Mother's Milk ◽  
Mother’S Milk ◽  
The Rich ◽  
Liquid Chromatographic

Background: Human milk contains the nutrients necessary for the growth and development of babies as it contains essential bioactive components to support the immune system. Galactooligosaccharides which are important indigestible prebiotics, help multiply the growth of beneficial microorganisms selectively and inhibit the growth of the pathogenic organism. The nutrition of the mother is essential since it affects the composition of mother’s milk. Kefir affects the digestive system, lactose intolerance immune system, anti-microbial effects, probiotic and prebiotic features. However, there is no report on how kefir consumption may have effects on composition of mother’s milk. In this aspect, this study aimed to determine the effects of kefir consumption on the carbohydrate profiles of the mother’s milk. Methods: This study started immediately after birth, mothers were fed with 500 ml/day of kefir made from kefir grains for 30 days in the KF group. Mothers who are in the control group (KI) continued their regular diet. Mother’s milk was collected on the 10th, 20th, and 30th day and stored at 4ºC. Carbohydrate profile including GOS was determined using the liquid chromatographic method with the HI-PLEX column.Results: The mean lactose concentrations of mother’s milk who consumed kefir were 4,68; 4,72; 5,89 g/100ml on days 10th, 20th, and 30th, respectively. Glucose concentrations were 0,29; 0,08; 0,21 g/100ml on 10th, 20th, 30th days, respectively. For the mother’s milk samples in the control group, the averages of lactose concentration were 5,42; 5,73; 5,51 g/100ml on days 10th, 20th, and 30th. GOS peaks were specified depending on the rich content of prebiotics. Conclusion: Consumption of authentic kefir may have effect on carbohydrate profile, including GOS of mother’s milk. Keywords: Human milk, kefir, prebiotic, galactooligosaccharides  

scholarly journals Tolerance of preterm formula versus pasteurized donor human milk in very preterm infants: a randomized non-inferiority trial

2018 ◽  
Vol 44 (1) ◽  
Author(s):  
Simonetta Costa ◽  
Luca Maggio ◽  
Giovanni Alighieri ◽  
Giovanni Barone ◽  
Francesco Cota ◽  
...  
Keyword(s):  
Human Milk ◽  
Preterm Infants ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Donor Human Milk ◽  
Preterm Formula

scholarly journals Impact of Donor Human Milk in the Preterm Very Low Birth Weight Gut Transcriptome Profile by Use of Exfoliated Intestinal Cells

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2677 ◽  
Author(s):  
Anna Parra-Llorca ◽  
María Gormaz ◽  
Sheila Lorente-Pozo ◽  
Maria Cernada ◽  
Ana García-Robles ◽  
...  
Keyword(s):  
Human Milk ◽  
Preterm Infants ◽  
Very Low Birth Weight ◽  
Principal Component ◽  
Postnatal Period ◽  
Intestinal Cells ◽  
Donor Human Milk ◽  
Genome Wide ◽  
Alpha Gene ◽  
Cytosolic Factor

Background: Own mother’s milk (OMM) is the optimal nutrition for preterm infants. However, pasteurized donor human milk (DHM) is a valid alternative. We explored the differences of the transcriptome in exfoliated epithelial intestinal cells (EEIC) of preterm infants receiving full feed with OMM or DHM. Methods: The prospective observational study included preterm infants ≤ 32 weeks’ gestation and/or ≤1500 g birthweight. Total RNA from EEIC were processed for genome-wide expression analysis. Results: Principal component analysis and unsupervised hierarchical clustering analysis revealed two clustered groups corresponding to the OMM and DHM groups that showed differences in the gene expression profile in 1629 transcripts. The OMM group overexpressed lactalbumin alpha gene (LALBA), Cytochrome C oxidase subunit I gene (COX1) and caseins kappa gene (CSN3), beta gene (CSN2) and alpha gene (CSN1S1) and underexpressed Neutrophil Cytosolic Factor 1 gene (NCF1) compared to the DHM group. Conclusions: The transcriptomic analysis of EEIC showed that OMM induced a differential expression of specific genes that may contribute to a more efficient response to a pro-oxidant challenge early in the postnatal period when preterm infants are at a higher risk of oxidative stress. The use of OMM should be strongly promoted in preterm infants.

Donor Human Milk for Preterm Infants

PEDIATRICS ◽  
2012 ◽  
Vol 130 (2) ◽  
pp. e462-e462 ◽  
Author(s):  
W. McGuire
Keyword(s):  
Human Milk ◽  
Preterm Infants ◽  
Donor Human Milk
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