Prospective study of dietary intake of branched‐chain amino acids and the risk of primary open‐angle glaucoma

2021 ◽  
Author(s):  
Akiko Hanyuda ◽  
Bernard A. Rosner ◽  
Janey L. Wiggs ◽  
Walter C. Willett ◽  
Kazuo Tsubota ◽  
...  
Keyword(s):  
Amino Acids ◽  
Dietary Intake ◽  
Prospective Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Branched Chain Amino Acids ◽  
Open Angle ◽  
Branched Chain

scholarly journals Dietary intake of branched-chain amino acids in relation to depression, anxiety and psychological distress

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Glareh Koochakpoor ◽  
Asma Salari-Moghaddam ◽  
Ammar Hassanzadeh Keshteli ◽  
Hamid Afshar ◽  
Ahmad Esmaillzadeh ◽  
...  
Keyword(s):  
Amino Acids ◽  
Psychological Distress ◽  
Dietary Intake ◽  
Psychological Disorders ◽  
Branched Chain Amino Acids ◽  
Inverse Association ◽  
Depression And Anxiety ◽  
Lower Odds ◽  
Significant Inverse Association ◽  
Branched Chain

Abstract Background There is no previous study that examined the association between branched-chain amino acids (BCAAs) intake and odds of psychological disorders. The aim of this study was to investigate the association between dietary BCAAs and odds of psychological disorders including depression, anxiety, and psychological distress in a large sample of Iranian adults. Methods In this cross-sectional study on 3175 Iranian adults aged 18–55 years, a validated food frequency questionnaire was used to assess dietary intakes. BCAAs intake was computed by summing up the amount of valine, leucine, and isoleucine intake from all food items in the questionnaire. Psychological health was examined through the use of Iranian validated version of the Hospital Anxiety and Depression Scale (HADS). Psychological distress was assessed using General Health Questionnaire (GHQ). For depression and anxiety, scores of 8 or more on either subscale were considered as psychological disorders and scores of 0–7 were defined as “normal”. In terms of psychological distress, the score of 4 or more was defined as psychological distress. Results Mean age of study participants was 36.2 ± 7.8 years. Overall, 26.4% (n = 837) of study subjects had depression, 11.9% (n = 378) had anxiety and 20.9% (n = 665) were affected by psychological distress. After controlling for potential confounders, participants in the highest tertile of total BCAAs intake had lower odds of depression (OR: 0.76; 95% CI: 0.60–0.96) and anxiety (OR: 0.66; 95% CI: 0.47–0.91) compared with those in the lowest tertile. Participants in the top tertile of valine intake had a lower odds of depression (OR: 0.76; 95% CI: 0.60–0.96) and anxiety (OR: 0.65; 95% CI: 0.47–0.90) compared with those in the bottom tertile. A significant inverse association was also seen between leucine intake and depression (OR: 0.77; 95% CI: 0.61–0.98) and anxiety (OR: 0.66; 95% CI: 0.47–0.91). In addition, a significant inverse association was observed between isoleucine intake and odds of depression (OR: 0.75; 95% CI: 0.59–0.95) and anxiety (OR: 0.62; 95% CI: 0.45–0.86). There was no significant association between isoleucine intake and odds of psychological distress. Conclusion Evidence indicating an inverse association between dietary intake of BCAAs and odds of depression and anxiety was found. Prospective studies are required to confirm these findings.

Prospective Study of Alcohol Consumption and the Risk of Primary Open-Angle Glaucoma

2007 ◽  
Vol 14 (3) ◽  
pp. 141-147 ◽  
Author(s):  
Jae H. Kang ◽  
Walter C. Willett ◽  
Bernard A. Rosner ◽  
Susan E. Hankinson ◽  
Louis R. Pasquale
Keyword(s):  
Alcohol Consumption ◽  
Prospective Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle

scholarly journals Relationships between Obesity, Nutrient Supply and Primary Open Angle Glaucoma in Koreans

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 878
Author(s):  
Jae Yeun Lee ◽  
Joon Mo Kim ◽  
Kyoung Yong Lee ◽  
Bokyung Kim ◽  
Mi Yeon Lee ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Dietary Intake ◽  
Large Scale ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Multivariate Logistic Regression Analysis ◽  
Open Angle ◽  
Cross Sectional Survey ◽  
Increased Risk ◽  
Calcium Phosphorus

To investigate the association between nutrient intake and primary open angle glaucoma (POAG) in Koreans, a population-based, cross-sectional survey, the Korean National Health and Nutrition Examination Survey, was analyzed. Glaucoma diagnosis was based on criteria established by the International Society of Geographic and Epidemiologic Ophthalmology. Multivariate regression analysis was used to assess the correlation between dietary intake and the prevalence of POAG in all enrolled subjects. In the low Body mass index(BMI) group (BMI <18.5), females with POAG had significantly lower intakes of energy, protein, fat, carbohydrate, ash, calcium, phosphorus, sodium, potassium, vitamin A, B-carotene, thiamin, riboflavin, and vitamin C than their non-glaucoma counterparts, based on a multivariate logistic regression analysis (all p < 0.05). In females with a medium BMI (18.5 ≤ BMI < 23), POAG showed a significant association with lower food intake, energy, protein, calcium, phosphorus, potassium, thiamin and niacin. (all p < 0.05). Lower protein thiamine intake in medium BMI males was related to POAG. Low dietary intake of several nutrients showed an association with glaucoma in low BMI female subjects. An insufficient intake of certain nutrients may be associated with an increased risk of glaucoma in Koreans. Further large-scale cohort studies are needed to determine how specific nutrients alter the risk of glaucoma.

scholarly journals Prospective study of flavonoid intake and risk of primary open-angle glaucoma

2018 ◽  
Vol 96 (6) ◽  
pp. e692-e700 ◽  
Author(s):  
Jae H. Kang ◽  
Kerry L. Ivey ◽  
Tahani Boumenna ◽  
Bernard Rosner ◽  
Janey L. Wiggs ◽  
...  
Keyword(s):  
Prospective Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Flavonoid Intake

scholarly journals Association of dietary intake of branched-chain amino acids with long-term risks of cardiovascular disease, cancer and all-cause mortality

2021 ◽  
pp. 1-60
Author(s):  
Binbin Xu ◽  
Meng Wang ◽  
Liyuan Pu ◽  
Chang Shu ◽  
Lian Li ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Amino Acids ◽  
Dietary Intake ◽  
The United States ◽  
Branched Chain Amino Acids ◽  
Dietary Intakes ◽  
All Cause Mortality ◽  
Nationally Representative ◽  
Branched Chain

Abstract Objectives: Studies on associations between dietary intake of branched-chain amino acids (BCAAs) and long-term risks of cardiovascular disease (CVD), cancer, and all-cause mortality have yielded inconclusive results. This study aimed to investigate the associations between dietary BCAA intake and long-term risks of CVD, cancer, and all-cause mortality in nationwide survey participants aged ≥18. Design: This was a prospective cohort study of a nationally representative sample of 14,397 adults aged ≥18 who participated in the United States National Health and Nutrition Examination Survey III (NHANES III). Dietary intakes of BCAAs (leucine, isoleucine, and valine) were determined from the total nutrient intake document. The main outcomes were CVD, cancer, and all-cause mortality. Results: During 289,406 person-years of follow-up, we identified 4,219 deaths, including 1,133 from CVD and 926 from cancer. After multivariate adjustment, the hazard ratios (95% confidence intervals) of all-cause mortality in the highest dietary BCAA and isoleucine intake quintile (reference: lowest quintiles) were 0.68 (0.48–0.97) and 0.68 (0.48–0.97), respectively. Each one-standard-deviation increase in total dietary BCAA or isoleucine intake was associated with an 18% or 21% decrease in the risk of all-cause mortality, respectively. The serum triglyceride (TG) concentration was found to modify the association between the dietary BCAA intake and all-cause mortality (P for interaction = 0.008). Conclusions: In a nationally representative cohort, higher dietary intakes of BCAAs and isoleucine were independently associated with a lower risk of all-cause mortality, and these associations were stronger in participants with higher serum TG concentrations.

AACE2021-A-1048: Effect of Dietary Intake of Branched Chain Amino Acids on Type 2 Diabetic Patients Control

2021 ◽  
Vol 27 (12) ◽  
pp. S39-S40
Author(s):  
Nehal Hammdy ◽  
Randa Salam ◽  
El Sayed Mahmoud Hammad ◽  
Samah Ahmed Abd El Shafy
Keyword(s):  
Amino Acids ◽  
Dietary Intake ◽  
Branched Chain Amino Acids ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Branched Chain ◽  
Type 2 Diabetic
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