Impeller geometry definition of the transventricular assist device

2020 ◽  
Vol 44 (8) ◽  
pp. 803-810 ◽  
Author(s):  
Gustavo Andrade ◽  
Oswaldo Horikawa ◽  
Evandro Drigo ◽  
Aron Andrade ◽  
Jose Cardoso
Heart & Lung ◽  
2014 ◽  
Vol 43 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Kristin E. Sandau ◽  
Barbara A. Hoglund ◽  
Carrie E. Weaver ◽  
Charlene Boisjolie ◽  
David Feldman

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Patrik Kovář ◽  
Tomáš Kaňka ◽  
Pavel Mačák ◽  
Adam Tater ◽  
Tomáš Vampola

Nowadays there are lots of methods using three-dimensional or quasi three-dimensional CFD analysis. Unfortunately, this approach is still very demanding, so that quick preliminary design algorithms have still its importance, even though simplified analytical model of radial compressor gives less accurate results. Obtained results can be used in later stages of the radial compressor (RC) design, such as definition of spatial impeller geometry and CFD computation. The article presents the influence of input parameters in the radial compressor design algorithm on the efficiency. The assembled mathematical model of RC is derived from the basic laws of continuum mechanics and can be used for a quick assessment of the preliminary design concept of the RC. A sensitivity analysis is performed on input parameters to select parameters that have the dominant effect on the monitored performance indicators. On the basis of the sensitivity analysis, a multicriteria optimization process was assembled to increase the performance parameters.


2020 ◽  
Vol 6 ◽  
Author(s):  
Sriram D Rao ◽  
Srinath Adusumalli ◽  
Jeremy A Mazurek

The development of pulmonary hypertension (PH) in patients with heart failure is associated with increased morbidity and mortality. In this article, the authors examine recent changes to the definition of PH in the setting of left heart disease (PH-LHD), and discuss its epidemiology, pathophysiology and prognosis. They also explore the complexities of diagnosing PH-LHD and the current evidence for the use of medical therapies, promising clinical trials and the role of left ventricular assist device and transplantation.


1966 ◽  
Vol 24 ◽  
pp. 3-5
Author(s):  
W. W. Morgan

1. The definition of “normal” stars in spectral classification changes with time; at the time of the publication of theYerkes Spectral Atlasthe term “normal” was applied to stars whose spectra could be fitted smoothly into a two-dimensional array. Thus, at that time, weak-lined spectra (RR Lyrae and HD 140283) would have been considered peculiar. At the present time we would tend to classify such spectra as “normal”—in a more complicated classification scheme which would have a parameter varying with metallic-line intensity within a specific spectral subdivision.


1975 ◽  
Vol 26 ◽  
pp. 21-26

An ideal definition of a reference coordinate system should meet the following general requirements:1. It should be as conceptually simple as possible, so its philosophy is well understood by the users.2. It should imply as few physical assumptions as possible. Wherever they are necessary, such assumptions should be of a very general character and, in particular, they should not be dependent upon astronomical and geophysical detailed theories.3. It should suggest a materialization that is dynamically stable and is accessible to observations with the required accuracy.


1979 ◽  
Vol 46 ◽  
pp. 125-149 ◽  
Author(s):  
David A. Allen

No paper of this nature should begin without a definition of symbiotic stars. It was Paul Merrill who, borrowing on his botanical background, coined the termsymbioticto describe apparently single stellar systems which combine the TiO absorption of M giants (temperature regime ≲ 3500 K) with He II emission (temperature regime ≳ 100,000 K). He and Milton Humason had in 1932 first drawn attention to three such stars: AX Per, CI Cyg and RW Hya. At the conclusion of the Mount Wilson Ha emission survey nearly a dozen had been identified, and Z And had become their type star. The numbers slowly grew, as much because the definition widened to include lower-excitation specimens as because new examples of the original type were found. In 1970 Wackerling listed 30; this was the last compendium of symbiotic stars published.


Author(s):  
K. T. Tokuyasu

During the past investigations of immunoferritin localization of intracellular antigens in ultrathin frozen sections, we found that the degree of negative staining required to delineate u1trastructural details was often too dense for the recognition of ferritin particles. The quality of positive staining of ultrathin frozen sections, on the other hand, has generally been far inferior to that attainable in conventional plastic embedded sections, particularly in the definition of membranes. As we discussed before, a main cause of this difficulty seemed to be the vulnerability of frozen sections to the damaging effects of air-water surface tension at the time of drying of the sections.Indeed, we found that the quality of positive staining is greatly improved when positively stained frozen sections are protected against the effects of surface tension by embedding them in thin layers of mechanically stable materials at the time of drying (unpublished).


Author(s):  
W. A. Shannon ◽  
M. A. Matlib

Numerous studies have dealt with the cytochemical localization of cytochrome oxidase via cytochrome c. More recent studies have dealt with indicating initial foci of this reaction by altering incubation pH (1) or postosmication procedure (2,3). The following study is an attempt to locate such foci by altering membrane permeability. It is thought that such alterations within the limits of maintaining morphological integrity of the membranes will ease the entry of exogenous substrates resulting in a much quicker oxidation and subsequently a more precise definition of the oxidative reaction.The diaminobenzidine (DAB) method of Seligman et al. (4) was used. Minced pieces of rat liver were incubated for 1 hr following toluene treatment (5,6). Experimental variations consisted of incubating fixed or unfixed tissues treated with toluene and unfixed tissues treated with toluene and subsequently fixed.


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