scholarly journals The CentriMag Centrifugal Blood Pump as a Benchmark for In Vitro Testing of Hemocompatibility in Implantable Ventricular Assist Devices

2014 ◽  
Vol 39 (2) ◽  
pp. 93-101 ◽  
Author(s):  
Chris H.H. Chan ◽  
Ina Laura Pieper ◽  
Rebecca Hambly ◽  
Gemma Radley ◽  
Alyssa Jones ◽  
...  
Keyword(s):  
Ventricular Assist Devices ◽  
Blood Pump ◽  
In Vitro Testing ◽  
Ventricular Assist ◽  
Centrifugal Blood Pump ◽  
Assist Devices

The Evaluation of Leukocytes in Response to the In Vitro Testing of Ventricular Assist Devices

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Chris H.H. Chan ◽  
Andrew Hilton ◽  
Graham Foster ◽  
Karl M. Hawkins ◽  
Nafiseh Badiei ◽  
...  
Keyword(s):  
Ventricular Assist Devices ◽  
In Vitro Testing ◽  
Ventricular Assist ◽  
Assist Devices

Centrifugal Blood Pump for Temporary Ventricular Assist Devices With Low Priming and Ceramic Bearings

2013 ◽  
Vol 37 (11) ◽  
pp. 942-945 ◽  
Author(s):  
Juliana Leme ◽  
Cibele da Silva ◽  
Jeison Fonseca ◽  
Bruno Utiyama da Silva ◽  
Beatriz Uebelhart ◽  
...  
Keyword(s):  
Ventricular Assist Devices ◽  
Blood Pump ◽  
Ventricular Assist ◽  
Centrifugal Blood Pump ◽  
Assist Devices

COMPUTER MANAGED IN VITRO TESTING OF VENTRICULAR ASSIST DEVICES

ASAIO Journal ◽  
1979 ◽  
Vol 25 (1) ◽  
pp. 192-196
Author(s):  
M. L. Pickard ◽  
W. OʼBaonon ◽  
M. J. Lloyd ◽  
M. E. Debakey
Keyword(s):  
Ventricular Assist Devices ◽  
In Vitro Testing ◽  
Ventricular Assist ◽  
Assist Devices

Effects of gravity on flow rate estimations of a centrifugal blood pump using the eccentric position of a levitated impeller

2020 ◽  
Vol 43 (12) ◽  
pp. 774-781
Author(s):  
Shuya Shida ◽  
Toru Masuzawa ◽  
Masahiro Osa
Keyword(s):  
Flow Rate ◽  
Ventricular Assist Devices ◽  
Blood Pump ◽  
Accurate Estimation ◽  
Ventricular Assist ◽  
Centrifugal Blood Pump ◽  
Assist Devices ◽  
Flow Estimation ◽  
Magnetically Levitated ◽  
Gravity Direction

Implantable ventricular assist devices are a type of mechanical circulatory support for assisting the pumping of the heart. Accurate estimation of the flow rate through such devices is critical to ensure effective performance. A novel method for estimating the flow rate using the passively stabilized position of a magnetically levitated impeller was developed by our group. However, the performance of the method is affected by the gravity vector, which depends on the patient’s posture. In this study, the effects of gravity on the flow estimation method are analyzed, and a compensation method is proposed. The magnetically levitated impeller is axially suspended and radially restricted by passive stability in a centrifugal blood pump developed by our group. The gravity effects were evaluated by analyzing the relationships between the radial position of the magnetically levitated impeller and the flow rate with respect to the gravity direction. Accurate estimation of the flow rate could not be achieved when the direction of gravity with respect to impeller was unknown. A mean absolute error of up to 4.89 L/min was obtained for flow rate measurement range of 0–5 L/min. However, analysis of the equilibrium of forces on the passively stabilized impeller indicated that the effects of gravity on the flow estimation could be compensated by performing additional measurements of the gravity direction with respect to impeller. The method for compensating the effects of gravity on the flow estimation should improve the performance of therapy with the implantable ventricular assist devices.

scholarly journals Response of a physiological controller for ventricular assist devices during acute patho-physiological events: an in vitro study

2017 ◽  
Vol 62 (6) ◽  
pp. 623-633 ◽  
Author(s):  
Anastasios Petrou ◽  
Panagiotis Pergantis ◽  
Gregor Ochsner ◽  
Raffael Amacher ◽  
Thomas Krabatsch ◽  
...  
Keyword(s):  
Valsalva Maneuver ◽  
Constant Speed ◽  
Ventricular Assist Devices ◽  
Moving Window ◽  
Clinical Implementation ◽  
Premature Ventricular Contractions ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Mock Circulation

AbstractThe current paper analyzes the performance of a physiological controller for turbodynamic ventricular assist devices (tVADs) during acute patho-physiological events. The numerical model of the human blood circulation implemented on our hybrid mock circulation was extended in order to simulate the Valsalva maneuver (VM) and premature ventricular contractions (PVCs). The performance of an end-diastolic volume (EDV)-based physiological controller for VADs, named preload responsive speed (PRS) controller was evaluated under VM and PVCs. A slow and a fast response of the PRS controller were implemented by using a 3 s moving window, and a beat-to-beat method, respectively, to extract the EDV index. The hemodynamics of a pathological circulation, assisted by a tVAD controlled by the PRS controller were analyzed and compared with a constant speed support case. The results show that the PRS controller prevented suction during the VM with both methods, while with constant speed, this was not the case. On the other hand, the pump flow reduction with the PRS controller led to low aortic pressure, while it remained physiological with the constant speed control. Pump backflow was increased when the moving window was used but it avoided sudden undesirable speed changes, which occurred during PVCs with the beat-to-beat method. In a possible clinical implementation of any physiological controller, the desired performance during frequent clinical acute scenarios should be considered.

Defibrillator-Heart Pump: An Implantable Ventricular Assist Device With Integrated Defibrillator Component—The First In Vitro Testing

2019 ◽  
Vol 26 (6) ◽  
pp. 720-724
Author(s):  
Anas Aboud ◽  
Kai Liebing ◽  
Charlie Abraham ◽  
Jan-Christian Reil ◽  
Yara Turkistani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Therapeutic Option ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
In Vitro Testing ◽  
Left Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Heart Pump ◽  
Increased Risk

Left ventricular assist devices (LVADs) are an important therapeutic option for patients with end-stage heart failure waiting for heart transplantation or in older patients as definite therapy for heart failure. Interestingly, about 62% of patients receiving LVADs do not have an automatic implantable cardioverter-defibrillator (AICD) at the time of implantation, although these patients have increased risk of being confronted with dangerous arrhythmia. Therefore, an LVAD system including AICD function is a reasonable alternative for such heart failure patients thereby avoiding a second surgical intervention for AICD implantation. In this article, a newly developed system including LVAD and AICD function is introduced, and we also report its first in vitro testing.

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