scholarly journals Gestational age is more important for short-term neonatal outcome than microbial invasion of the amniotic cavity or intra-amniotic inflammation in preterm prelabor rupture of membranes

2016 ◽  
Vol 95 (8) ◽  
pp. 926-933 ◽  
Author(s):  
Adriano Rodríguez-Trujillo ◽  
Teresa Cobo ◽  
Irene Vives ◽  
Jordi Bosch ◽  
Marian Kacerovsky ◽  
...  
Keyword(s):  
Gestational Age ◽  
Neonatal Outcome ◽  
Short Term ◽  
Amniotic Cavity ◽  
Microbial Invasion ◽  
Prelabor Rupture Of Membranes

scholarly journals Impact of microbial invasion of amniotic cavity and the type of microorganisms on short-term neonatal outcome in women with preterm labor and intact membranes

2017 ◽  
Vol 96 (5) ◽  
pp. 570-579 ◽  
Author(s):  
Teresa Cobo ◽  
Irene Vives ◽  
Adriano Rodríguez-Trujillo ◽  
Clara Murillo ◽  
Martina A. Ángeles ◽  
...  
Keyword(s):  
Preterm Labor ◽  
Neonatal Outcome ◽  
Short Term ◽  
Amniotic Cavity ◽  
Microbial Invasion

scholarly journals Neonatal management and outcome after thoracoamniotic shunt placement for fetal hydrothorax

2017 ◽  
Vol 103 (3) ◽  
pp. F245-F249 ◽  
Author(s):  
Ruben S G M Witlox ◽  
Frans J C M Klumper ◽  
Arjan B te Pas ◽  
Erik W van Zwet ◽  
Dick Oepkes ◽  
...  
Keyword(s):  
Gestational Age ◽  
Neonatal Outcome ◽  
Rescue Therapy ◽  
High Frequency Ventilation ◽  
Short Term ◽  
Course Of Disease ◽  
Shunt Placement ◽  
Frequency Ventilation ◽  
Thoracoamniotic Shunt ◽  
Time Of Intervention

AimTo evaluate the short-term neonatal outcome after fetal thoracoamniotic shunt placement for isolated hydrothorax.MethodsRetrospective evaluation of infants with isolated hydrothorax treated with thoracoamniotic shunt placement at our fetal therapy centre between 2001 and 2016.ResultsIn total 48 fetuses were treated with a thoracoamniotic shunt. All fetuses had signs of hydrops at the time of intervention. Median (IQR) gestational age at shunting was 28.7 (24.4–31.3) weeks. Forty-one of 48 (85%) fetuses were born alive at a median (IQR) gestational age of 34.4 (31.1–36.7) weeks. In one child the course of disease after birth was unknown (this child was excluded from further analyses). After birth, 24/40 (60%) children had signs of pleural effusion and 12/40 (30%) needed a thoracic shunt for continuous pleural drainage. Twenty-one (53%) children required mechanical ventilation, of whom 13 (33%) needed high-frequency ventilation as rescue therapy. Overall 30/40 (75%) infants survived the neonatal period. Neonatal survival rate was significantly higher when infants were born ≥32 weeks’ gestation as compared with <32 weeks: 93% (26/28) versus 33% (4/12), p<0.01.ConclusionPostnatal course of hydropic fetuses treated with thoracoamniotic shunt for isolated hydrothorax is often complicated by respiratory failure and persistent pleural effusions. Neonatal survival is good provided delivery occurs at or after 32 weeks’ gestation.

scholarly journals IgGFc-binding protein in pregnancies complicated by spontaneous preterm delivery: a retrospective cohort study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jaroslav Stranik ◽  
Marian Kacerovsky ◽  
Ondrej Soucek ◽  
Martina Kolackova ◽  
Ivana Musilova ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Preterm Labor ◽  
Operating Characteristic ◽  
Binding Protein ◽  
Characteristic Curve ◽  
Enzyme Linked Immunosorbent Assay ◽  
Amniotic Cavity ◽  
Spontaneous Preterm Delivery ◽  
Microbial Invasion ◽  
Prelabor Rupture Of Membranes

AbstractTo determine the IgGFc-binding protein (FcgammaBP) concentration in amniotic and cervical fluids in preterm prelabor rupture of membranes (PPROM) and preterm labor with intact membranes (PTL) and to assess the diagnostic indices of FcgammaBP to predict intra-amniotic infection (the presence of both microbial invasion of the amniotic cavity and intra-amniotic inflammation). In this study, we included 170 and 79 women with PPROM and PTL, respectively. Paired cervical and amniotic fluid samples were obtained using a Dacron polyester swab and transabdominal amniocentesis, respectively. The FcgammaBP concentrations in the samples were assessed using an enzyme-linked immunosorbent assay. The presence of intra-amniotic infection was associated with elevated FcgammaBP concentrations in pregnancies with PPROM and PTL [PPROM—presence: 86 ng/mL vs. absence: 13 ng/mL, p < 0.0001, area under receiver operating characteristic curve (AUC) = 0.94; PTL—presence: 140 ng/mL vs. absence: 22 ng/mL, p < 0.0001, AUC = 0.86]. In cervical fluid, the concentrations of FcgammaBP were elevated in the presence of intra-amniotic infection in pregnancies with PPROM only (presence: 345 ng/mL vs. absence: 60 ng/mL, p < 0.0001, AUC = 0.93). FcgammaBP in amniotic fluid might be a marker of intra-amniotic infection in women with both PPROM and PTL However, in cervical fluid, it is only observed in women with PPROM.

scholarly journals sFlt-1/PlGF Ratio in Prediction of Short-Term Neonatal Outcome of Small for Gestational Age Neonates

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 718
Author(s):  
Jacek Witwicki ◽  
Katarzyna Chaberek ◽  
Natalia Szymecka-Samaha ◽  
Adam Krysiak ◽  
Paweł Pietruski ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Neonatal Outcome ◽  
Perinatal Outcomes ◽  
High Ratio ◽  
Short Term ◽  
Adverse Perinatal Outcomes ◽  
Lower Birthweight ◽  
Plgf Ratio ◽  
Normotensive Pregnancy

Background: Small for gestational age is a pregnancy complication associated with a variety of adverse perinatal outcomes. The aim of the study was to investigate if sFlt-1/PlGF ratio is related to adverse short-term neonatal outcome in neonates small for gestational age in normotensive pregnancy. Methods: A prospective observational study was conducted. Serum sFlt-1/PlGF ratio was measured in women in singleton gestation diagnosed with fetus small for gestational age. Short-term neonatal outcome analyzed in the period between birth and discharge home. Results: Eighty-two women were included. Women with sFlt-1/PlGF ratio ≥33 gave birth to neonates with lower birthweight at lower gestational age. Neonates from high ratio group suffered from respiratory disorders and NEC significantly more often. They were hospitalized at NICU more often and were discharged home significantly later. sFlt-1/PlGF ratio predicted combined neonatal outcome with sensitivity of 73% and specificity of 82.2%. Conclusions: sFlt-1/PlGF ratio is a useful toll in prediction of short-term adverse neonatal outcome in SGA pregnancies.

446: Impact of sterile intra-amniotic inflammation on short term neonatal outcome in women with preterm prelabor rupture of membranes

2017 ◽  
Vol 216 (1) ◽  
pp. S263-S264
Author(s):  
Clara Murillo-Bravo ◽  
Cristina Martí-Delgado ◽  
Adriano Rodriguez-Trujillo ◽  
Irene Vives ◽  
Eduard Gratacós ◽  
...  
Keyword(s):  
Neonatal Outcome ◽  
Short Term ◽  
Prelabor Rupture Of Membranes

scholarly journals Microbial invasion of the amniotic cavity in pregnancies with small-for-gestational-age fetuses

2010 ◽  
Vol 38 (5) ◽  
Author(s):  
Daniel B. DiGiulio ◽  
Maria Teresa Gervasi ◽  
Roberto Romero ◽  
Edi Vaisbuch ◽  
Shali Mazaki-Tovi ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Amniotic Cavity ◽  
Microbial Invasion
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