Effects of stocking density and dietary phosphorus levels on the growth performance, antioxidant capacity, and nitrogen and phosphorus emissions of juvenile blunt snout bream ( Megalobrama amblycephala )

2020 ◽  
Author(s):  
Heng Yu ◽  
Qiang Yang ◽  
Hualiang Liang ◽  
Mingchun Ren ◽  
Xianping Ge ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Stocking Density ◽  
Megalobrama Amblycephala ◽  
Nitrogen And Phosphorus ◽  
Blunt Snout Bream ◽  
Dietary Phosphorus ◽  
Phosphorus Levels

Effect of supplementation of nicotinamide and sodium butyrate on the growth performance, liver mitochondrial function and gut microbiota of broilers at high stocking density

2019 ◽  
Vol 10 (11) ◽  
pp. 7081-7090 ◽  
Author(s):  
Yuqin Wu ◽  
Youli Wang ◽  
Dafei Yin ◽  
Wei Wu ◽  
Xiaoying Sun ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Antioxidant Capacity ◽  
Growth Performance ◽  
Sodium Butyrate ◽  
Mitochondrial Function ◽  
Stocking Density

Dietary supplemental with nicotinamide and butyrate sodium improve mitochondrial function, antioxidant capacity, and gut microbiota.

scholarly journals Tributyrin Plays an Important Role in Regulating the Growth and Health Status of Juvenile Blunt Snout Bream (Megalobrama amblycephala), as Evidenced by Pathological Examination

2021 ◽  
Vol 12 ◽  
Author(s):  
Hualiang Liang ◽  
Ke Ji ◽  
Xianping Ge ◽  
Bingwen Xi ◽  
Mingchun Ren ◽  
...  
Keyword(s):  
Health Status ◽  
Inflammatory Response ◽  
Antioxidant Capacity ◽  
Inflammatory Cytokines ◽  
Pathological Examination ◽  
Megalobrama Amblycephala ◽  
Intestinal Damage ◽  
Mrna Levels ◽  
Blunt Snout Bream ◽  
Tnf Α

The present study aimed to assess the role of tributyrin (TB) in regulating the growth and health status of juvenile blunt snout bream (Megalobrama amblycephala) through an 8-week feeding experiment. Six groups were fed experimental diets with added TB percentages of 0% (control group), 0.03%, 0.06%, 0.09%, 0.12% and 0.15%. The present results showed that TB supplementation in feed had some positive impacts on FW, WG, FCR and SGR, and the best results were found in the 0.06% TB group (P<0.05). However, TB supplementation in feed had no significant effects on SR, CF, VSI or whole-body composition (P>0.05). TB supplementation in feed increased antioxidant capacity and immunological capacity and attenuated the inflammatory response by increasing the activity of T-SOD, GPx, CAT and the levels of anti-inflammatory cytokines (IL-10 and TGF-β) and decreasing the levels of MDA and anti-inflammatory cytokines (TNF-α) (P<0.05). Furthermore, TB supplementation improved immunity by increasing the levels of immunoglobulins (IgM and IgG), C3 and IFN-γ (P<0.05). Surprisingly, 0.06%-0.12% TB supplementation significantly increased the content of IL-1β (P<0.05). However, TB supplementation in feed had no significant effects on the plasma content of GSH, HSP70, IL-8 and the activity of T-AOC (P>0.05). The possible mechanism was that TB activated PI3K/Akt/Nrf2 and inhibits the NF-κB signaling pathway, further regulating the mRNA levels of key genes with antioxidant capacity and the inflammatory response; for example, it increased the mRNA levels of Nrf2, Cu/Zn-SOD, HO-1, CAT, Akt, PI3K, GPx, IL-10, and TGF-β and decreased the mRNA levels of NF-κB and TNF-α (P<0.05). In addition, 0.06%-0.15% TB supplementation significantly increased the mRNA levels of IL-1β (P<0.05). TB supplementation in feed had no significant effects on the mRNA levels of HSP70, Mn-SOD and IL-8 (P>0.05). Evidence was presented that TB supplementation decreased the mortality rate caused by Aeromonas hydrophila challenge. In pathological examination, TB supplementation prevented hepatic and intestinal damage. Generally, TB supplementation improved the growth performance of juvenile blunt snout bream. Furthermore, TB supplementation activated PI3K/Akt/Nrf2 and inhibited the NF-κB signaling pathway, regulating health status and preventing hepatic and intestinal damage.

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