Amyloidosis of the distal ileum: A stricturing lesion is not always Crohn's disease

2021 ◽  
Author(s):  
Brigid Wolf ◽  
Gavin Joe ◽  
Chris Dow ◽  
Hinna Azher ◽  
Justin M. Yeung
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Distal Ileum

Fecal α1-antitrypsin clearance as a marker of clinical relapse in patients with Crohn's disease of the distal ileum

2003 ◽  
Vol 15 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Livia Biancone ◽  
Massimo Fantini ◽  
Claudio Tosti ◽  
Rosamaria Bozzi ◽  
Piero Vavassori ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Distal Ileum ◽  
Clinical Relapse

scholarly journals Endoscopic stricturotomy and ileo-colonic resection in patients with primary Crohn’s disease-related distal ileum strictures

2020 ◽  
Vol 8 (4) ◽  
pp. 312-318
Author(s):  
Nan Lan ◽  
Tracy L Hull ◽  
Bo Shen
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Distal Ileum ◽  
Colonic Resection ◽  
Free Survival ◽  
Anastomotic Strictures ◽  
Procedural Complications ◽  
Inflammatory Bowel ◽  
Surgery Rates

Abstract Background Stricture is a common presentation of Crohn’s disease with the site of prevalence being the distal ileum. This study aimed to compare the efficacy and safety of patients with primary distal ileum stricture treated with endoscopic stricturotomy (ESt) vs ileo-colonic resection (ICR). Methods All consecutive patients with primary distal ileum stricture that were treated with ESt and/or ICR were extracted from the interventional inflammatory bowel disease (i-IBD) unit from 2001 to 2016. All patients with a stricture >5 cm or those with anastomotic strictures were excluded from the study. The primary outcomes were surgery-free survival and post-procedural complications. Results A total of 13 patients receiving ESt and 32 patients receiving ICR were included in this study. Although the length of the stricture is comparable between the two groups (2.4 ± 0.9 vs 3.0 ± 1.1 cm, P = 0.17), patients who received surgery had a more complicated obstruction presented by the high pre-stenosis proximal dilation rate (67.7% vs 9.1%, P = 0.001). All patients in both groups achieved immediate technical success after treatment. The median follow-up durations were 1.8 and 1.5 years in the ESt and ICR groups, respectively. The subsequent surgery rates were similar between the two groups (15.4% vs 18.8%, P = 0.79) and the overall surgery-free survival was also comparable between the two groups (P = 0.98). Post-procedural adverse events were seen in 2/29 ESt procedures (6.9% per procedure) and 8/32 (25.0%) patients receiving ICR (P = 0.05). Conclusions ESt achieved comparable stricture-related surgery-free survival as ICR, while ESt had a numerically lower post-operative complication rate.

scholarly journals Crohn's disease of the distal ileum.

Gut ◽  
1980 ◽  
Vol 21 (11) ◽  
pp. 933-940 ◽  
Author(s):  
C S Higgens ◽  
R N Allan
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Distal Ileum

Analysis of clinical course of postoperative recurrence in Crohn's Disease of distal ileum

1992 ◽  
Vol 37 (2) ◽  
pp. 215-219 ◽  
Author(s):  
F. Pallone ◽  
Monica Boirivant ◽  
Maria Antonietta Stazi ◽  
R. Cosintino ◽  
C. Prantera ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Clinical Course ◽  
Postoperative Recurrence ◽  
Distal Ileum

scholarly journals Aphthous Esophagael Ulceration: A Novel Presentation of Crohn’s Disease?

1994 ◽  
Vol 8 (2) ◽  
pp. 101-104 ◽  
Author(s):  
Paul L Beck ◽  
Philip K Blustein ◽  
Melvin A Andersen
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Giant Cells ◽  
Distal Ileum ◽  
Cell Hyperplasia ◽  
The Past ◽  
Bacterial Cultures ◽  
Aphthous Ulcers ◽  
Lymphoid Aggregates

Crohn’s disease (CD) commonly presents as involvement of the small bowel or colon - the esophagus is rarely involved. The authors describe the case of a 45-year-old woman who presented with odynophagia and was found to have aphthous ulcers of the esophagus. On questioning, she admitted to three to four episodes of nonbloody diarrhea, each lasting less than one week, over the past two years. The patient denied other symptoms of gastrointestinal, collagen-vascular, respiratory or cardiovascular disease. Viral, fungal and bacterial cultures of blood, stool and tissue biopsies were all negative. A small bowel enema showed inflammation of the distal ileum. Colonoscopy revealed patchy areas of inflammation of the colon and distal ileum. Biopsies from the esophagus, duodenum, terminal ileum and colon showed chronic inflammation, lymphoid aggregates, goblet cell hyperplasia (in the colon) and crypt abscesses. Giant cells, granulomas and fissures were not evident in any of the biopsies. The patient failed to respond to a three-week course of omeprazole, but her symptoms resolved within three days of starting prednisone. The exact cause of the esophageal ulcerations is unknown but most likely is CD of the esophagus.

40 P Doppler ultrasound of the distal ileum for assessing the effect of medical therapy in children with active Crohn's disease

2002 ◽  
Vol 34 ◽  
pp. A86
Author(s):  
A. Laghi ◽  
P. Paolantonio ◽  
A.L. Grandinetti ◽  
M. Bueno de Mesquita ◽  
A. Ambrosini ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Doppler Ultrasound ◽  
Medical Therapy ◽  
Distal Ileum

On-table endoscopy to define strictures and resection margins: experience from 178 operations for Crohn's disease using intraoperative endoscopy

2001 ◽  
Vol 3 (Supplement 2) ◽  
pp. 58-62
Author(s):  
G. Olaison ◽  
P. Andersson ◽  
P. Myrelid ◽  
K. Smedh ◽  
J. Soderholm ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Resection Margins ◽  
Intraoperative Endoscopy
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