Gallbladder amyloidosis: a unique histopathological finding

2020 ◽  
Author(s):  
Rhys Rumley ◽  
Christopher Lim ◽  
Enoch Wong ◽  
Sayed Hassen
Keyword(s):  
Histopathological Finding

Abstract W P73: Inside Intramural Thrombus Formation with Inflammatory Reactions Is Relevant to the Rupture of Cerebral Aneurysms

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Yusuke Shimoda ◽  
Naoki Nakayama ◽  
Masaaki Hokari ◽  
Takeo Abumiya ◽  
Hideo Shichinohe ◽  
...  
Keyword(s):  
Thrombus Formation ◽  
Cerebral Aneurysms ◽  
Histopathological Finding ◽  
Internal Elastic Lamina ◽  
Electron Microscopic ◽  
Inflammatory Reactions ◽  
Aneurysmal Wall ◽  
The Common ◽  
Collagen Layer ◽  
Elastic Lamina

Background and Purpose: Although recent researches on cerebral aneurysms (CAs) have been performed with the hydrodynamic or the molecular biological technique, the mechanisms of rupture are not fully understood. The aim of this study is to assess the mechanism by a comparison between ruptured and un-ruptured CAs with histopathological and electron-microscopic analysis. Methods: We analyzed 33 CAs (24 ruptured, 9 un-ruptured) collected surgically after neck clipping. As for the ruptured CAs, we operated them within 24 hours from the onset. HE staining, Elastica Masson staining, PTAH staining, and CD68 immunohistochemical staining were performed with paraffin sections. Morphological analysis with Scanning Electron Microscopy (SEM) was performed with 6 CAs (3 ruptured, 3 un-ruptured). Results: The common histopathological finding in both ruptured and un-ruptured CAs was that the aneurysmal wall consisted mostly of thick collagen layer without normal internal elastic lamina and media. The characteristic histopathological finding in ruptured CAs was inside intramural thrombus formation with infiltration of CD68 positive cells at the rupture point. The common SEM finding in both ruptured and un-ruptured CAs was the denudation of endothelial cells and the exposure of a subendothelial amorphous or a fibrous surface. The characteristic SEM finding in ruptured CAs was the cluster formation of thick fibrin fibers with incorporation of macrophages and platelets. Conclusions: While the endothelial denudation, the disappearance of internal elastic lamina and media, and the predominance of collagen layer in the aneurysmal wall were common in both ruptured and un-ruptured CAs, inside intramural thrombus formation with inflammatory reactions was characteristic only in ruptured CAs. This result suggests that thrombo-inflammatory reactions in CAs may act as a trigger for ruptures.

scholarly journals The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Penvadee Pattanaprichakul ◽  
Kanokvalai Kulthanan ◽  
Sumanas Bunyaratavej ◽  
Sasima Eimpunth ◽  
Thanaporn Rungruang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Informed Consent ◽  
Bacterial Infection ◽  
Treatment Outcomes ◽  
Clinical Manifestations ◽  
Current Data ◽  
Histopathological Finding ◽  
Histopathological Findings ◽  
Naked Eye ◽  
Color Alteration

Background. Pitted keratolysis (PK) is a superficial bacterial infection diagnosed mainly by clinical manifestations. Current data on its dermoscopic and histopathological findings, and the correlation of those findings, are limited. Objectives. To evaluate the clinical manifestations, dermoscopic, and histopathological findings of PK and to determine the correlations. Methods. Forty naval cadets with PK and five cadets with normal feet were enrolled this cohort study and provided informed consent. Dermoscopy was independently applied and evaluated by 2 dermatologists. Shave biopsies were performed on 37 patients with PK. Results. Pits were the most common dermoscopic finding (88.1%). The dermoscope had more sensitivity for the detection of PK than the naked eye examinations. Apart from the pits and the presence of bacteria, the most common histopathological finding for PK was color alteration of keratin. The presence of bacteria correlated with interrupted dermatoglyphic lines and the color alteration of keratin. Moreover, the presence of bacteria at the base of pits was related to worse treatment outcomes. Conclusions. Dermoscopy is a useful tool for PK diagnosis. Color alteration of keratin is another histopathological finding for PK. The presence of bacteria is associated with worse treatment outcomes.

Pseudocheckerboard pattern: an interesting histopathological finding in mechanic's hands

2015 ◽  
Vol 43 (1) ◽  
pp. 5-11 ◽  
Author(s):  
Ayako Ito ◽  
Nanako Yamada ◽  
Yuichi Yoshida ◽  
Osamu Yamamoto
Keyword(s):  
Histopathological Finding ◽  
Mechanic’S Hands

Heterotopia of the tonsil

1996 ◽  
Vol 110 (6) ◽  
pp. 611-612 ◽  
Author(s):  
Deepa Bhargava ◽  
R. Raman ◽  
Rashid Khalfan Al Abri ◽  
Bharti Bushnurmath
Keyword(s):  
Histological Examination ◽  
Histopathological Finding ◽  
Recurrent Tonsillitis

AbstractThe histopathological finding of heterotopias or choristoma is rare. This paper describes two patients who presented with chronic recurrent tonsillitis and underwent tonsillectomy. Histological examination revealed heterotopic cartilage in the tonsil of one patient and bone in that otthe other.

scholarly journals Nephrocalcinosis in 2 young rats: a case report

1980 ◽  
Vol 14 (3) ◽  
pp. 241-242 ◽  
Author(s):  
Jerald Silverman ◽  
Abraham Rivenson
Keyword(s):  
Case Report ◽  
Histopathological Finding ◽  
Sprague Dawley ◽  
Young Rats ◽  
Corticomedullary Junction ◽  
Sprague Dawley Rats

Nephrocalcinosis was diagnosed as an incidental histopathological finding in 2 Sprague-Dawley rats of 150 g bodyweight, The calcified material was located along the entire corticomedullary junction. Dietary and other causes of nephrocalcinosis are discussed.

scholarly journals The Histopathological Finding of the Surgically Extracted Atypical Dome-Shaped Choroidal Osteoma

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Hirona Bessho ◽  
Hisanori Imai ◽  
Atsushi Azumi
Keyword(s):  
Definitive Diagnosis ◽  
Histopathological Finding ◽  
Exudative Retinal Detachment ◽  
Corrected Visual Acuity ◽  
Choroidal Osteoma ◽  
Choroidal Tumor ◽  
Landolt Ring ◽  
Pars Plana ◽  
Temporal Side ◽  
Funduscopic Examination

Purpose. To report a case of atypical dome-shaped choroidal osteoma, which was diagnosed by histopathological finding of surgically extracted tumor. Case Report. A 35-year-old woman presented with visual field abnormality in the left eye (OS). Her best-corrected visual acuity with Landolt ring chart was 1.0 OS. The funduscopic examination revealed a yellowish dome-shaped choroidal tumor located in the temporal side of the macula with exudative retinal detachment. 25-gauge pars plana vitrectomy and the extraction of the tumor were performed for the definitive diagnosis. Results. As a result of histopathological finding from the extracted tumor, she was diagnosed with choroidal osteoma. 10 months after the last surgery, the BCVA is 0.7 OS. The tumor is not relapsed. Conclusions. We must keep in mind that choroidal osteoma can be one of the differential diagnoses for the dome-shaped choroidal tumor.

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