Oncological safety of laparoscopic versus open colorectal cancer surgery in obesity: a systematic review and meta‐analysis

2019 ◽  
Vol 89 (12) ◽  
pp. 1549-1555 ◽  
Author(s):  
Stephen Bell ◽  
Joseph C. Kong ◽  
Peter W. G. Carne ◽  
Martin Chin ◽  
Paul Simpson ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Meta Analysis ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Oncological Safety

scholarly journals Does Intraperitoneal Chemotherapy Increase the Incidence of Anastomotic Leakage after Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Yu Yang ◽  
Yuxuan Li ◽  
Xiaohui Du
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Anastomotic Leakage ◽  
Incidence Rate ◽  
Intraperitoneal Chemotherapy ◽  
Meta Analysis ◽  
Abdominal Cavity ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Increased Risk

Purpose. To identify and evaluate the influence of intraperitoneal chemotherapy without hyperthermia (ICwh) to the incidence of anastomotic leakage (AL) after colorectal cancer surgery. Methods. A systematic review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses in order to review all studies investigating the relationship between ICwh and AL in patients undergoing colorectal surgery. The primary outcome was overall incidence rate of anastomotic leakage. Results. Four studies were included in the final review. ICwh was associated with an overall increased risk of anastomotic leakage [OR 2.05 (1.06, 3.98), P = 0.03 ]. But there was no significant increased incidence rate when fluorouracil was implanted into the abdominal cavity for ICwh [OR 2.48 (0.55, 11.10), P = 0.24 ]. Conclusions. This meta-analysis provides some evidence to suggest ICwh may increase the incidence of postoperative AL in colorectal cancer. However, fluorouracil implantation for ICwh does not increase the risk of AL, which seems to be a relatively safe method of ICwh.

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