scholarly journals Drug hypersensitivity in children: report from the pediatric task force of the EAACI Drug Allergy Interest Group

Allergy ◽  
2015 ◽  
Vol 71 (2) ◽  
pp. 149-161 ◽  
Author(s):  
E. R. Gomes ◽  
K. Brockow ◽  
S. Kuyucu ◽  
F. Saretta ◽  
F. Mori ◽  
...  
Allergy ◽  
2016 ◽  
Vol 71 (8) ◽  
pp. 1103-1134 ◽  
Author(s):  
C. Mayorga ◽  
G. Celik ◽  
P. Rouzaire ◽  
P. Whitaker ◽  
P. Bonadonna ◽  
...  

Allergy ◽  
2013 ◽  
Vol 68 (7) ◽  
pp. 844-852 ◽  
Author(s):  
K. Scherer ◽  
K. Brockow ◽  
W. Aberer ◽  
J. H. C. Gooi ◽  
P. Demoly ◽  
...  

Allergy ◽  
2016 ◽  
Vol 71 (11) ◽  
pp. 1533-1539 ◽  
Author(s):  
K. Brockow ◽  
W. Aberer ◽  
M. Atanaskovic-Markovic ◽  
S. Bavbek ◽  
A. Bircher ◽  
...  

Author(s):  
Mauro Pagani ◽  
Sevim Bavbek ◽  
Emilio Alvarez-Cuesta ◽  
patrizia Bonadonna ◽  
Josefina Cernadas ◽  
...  

Chemotherapeutic drugs have been widely used in the treatment of cancer disease for about 70 years and, even with the development of new therapies, they are still prescribed by oncologists, alone or in combination with other antineoplastic agents. All chemotherapies are able to provoke hypersensitivity reactions, even with different incidences, depending on the different class of these drugs, and these reactions are the third leading cause of fatal drug-induced anaphylaxis in the United States. In Europe deaths related to chemotherapy have also been reported. In particular, most reactions are provoked by platinum compounds, taxanes, epipodophyllotoxins and asparaginase. However, currently there are different points of view about the best procedures for the diagnosis, treatment and prevention of these reactions. Thus, the European Network on Drug Allergy and Drug Allergy Interest Group of the European Academy of Allergy and Clinical Immunology organized a task force to provide data and recommendations regarding the allergological work up in this field of drug hypersensitivity reactions. The aims of this position paper were to provide consensus on the investigation of HSRs to chemotherapeutic drugs and to give practical suggestions for clinicians that treat these patients, such as oncologists, allergologists and internists. Key sections cover: risk factors, pathogenesis, symptoms, role of skin tests, in vitro tests, indications and contraindications of drug provocation tests and desensitization of neoplastic patients with allergic reactions to chemotherapeutic drugs. Statements, recommendations and unmet needs were discussed and proposed at the end of each section.


Allergy ◽  
2020 ◽  
Vol 75 (11) ◽  
pp. 2753-2763 ◽  
Author(s):  
Gianna Moscato ◽  
Christian Apfelbacher ◽  
Knut Brockow ◽  
Chiara Eberle ◽  
Jon Genuneit ◽  
...  

2008 ◽  
Vol 88 (11) ◽  
pp. 1436-1443 ◽  
Author(s):  
Andrew JM Boulton ◽  
David G Armstrong ◽  
Stephen F Albert ◽  
Robert G Frykberg ◽  
Richard Hellman ◽  
...  

The following article1 is the report of an American Diabetes Association task force that summarizes the recent literature on tests and measures to identify people at risk for foot ulceration and to recommend what should be included in the comprehensive foot exam for adult patients with diabetes. Although this information would be timely and pertinent for physical therapists at any time, its content is particularly complementary to the content of PTJ's Special Issue on Diabetes. This article has been reprinted with permission of the American Diabetes Association from Boulton AJM, Armstrong DG, Albert SF, et al. Comprehensive foot examination and risk assessment: a report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists. Diabetes Care. 2008;31:1679-1685. DOI: 10.2337/dc08-9021. Available online at: http://care.diabetesjournals.org. Copyright ©2008 American Diabetes Association. From Diabetes Care®, Vol 31, 2008; 1679-1685. Reprinted with permission from The American Diabetes Association. Reference 1 Boulton AJM , ArmstrongDG, AlbertSF, . Comprehensive foot examination and risk assessment: a report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists. Diabetes Care. 2008;31:1679–1685.


Author(s):  
Feridun Gurlek ◽  
Eyyup Tasdemir

Background: Drug hypersensitivity reactions are considered public health problems due to associated morbidity and socioeconomic costs. The evaluation of health-related quality of life in patients with drug hypersensitivity is still a widely unconsidered topic. The aim of our study is to reveal the effects of drug allergy on the quality of life of patients who apply to our outpatient clinic with the complaint of drug allergy.Methods: This study is prospective a questionnaire study under supervision. Patients who applied to the University of Health Sciences, Bursa Postgraduate Research and Training Hospital Department of Allergy outpatient clinic between August 2019 and May 2020 with the complaint of drug allergy filled out the quality of life questionnaire (DrHy-Q), and short questionnaire of psychological well-being index (PGWBIs) under the supervision of a specialist physician before the diagnostic procedures.Results: The study was conducted with 150 cases and 73.3 % (n=110) of the cases were female and 26.7% (n=40) were male. No significant correlation was found between the demographic characteristics of the patients, the observed symptoms, the culprit drugs, familial and individual comorbid and psychological diseases, and DrHY-Q (p>0.05). DrHY-Q was only affected from the type of allergic reaction. A negative statistically significant weak correlation was also detected between the total DrHY-Q score and the PGWBI total score (r: -0.283; p<0.01).Conclusions: We found that DrHY-Q is sensitive to reaction type and able to discriminative type 1 and type 2 reactions (p=0.017; p<0.05). We think that more comprehensive studies are needed on this subject.


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