Abdominal normothermic regional perfusion in controlled DCD liver transplantation: outcomes and risk factors for graft loss

Author(s):  
Amelia J. Hessheimer ◽  
Gloria de la Rosa ◽  
Mikel Gastaca ◽  
Patricia Ruíz ◽  
Alejandra Otero ◽  
...  
2009 ◽  
Vol 87 (9) ◽  
pp. 1387-1393 ◽  
Author(s):  
Walter C. Hellinger ◽  
Julia E. Crook ◽  
Michael G. Heckman ◽  
Nancy N. Diehl ◽  
Jefree A. Shalev ◽  
...  

2018 ◽  
Vol 102 ◽  
pp. S380 ◽  
Author(s):  
Amelia Hessheimer ◽  
Elisabeth Coll ◽  
Andrés Valdivieso ◽  
Manuel Gómez ◽  
Julio Santoyo ◽  
...  

2018 ◽  
Author(s):  
Lauren S Jones ◽  
Marina Serper

In this review, we provide an overview of the most current evidence on the prevalence, risk factors, and consequences of medication non-adherence (NA) in liver transplant recipients. Despite the improvement in long-term liver transplantation outcomes, medication NA is the leading cause of graft failure, graft rejection, and poor clinical outcomes. We examine methods of measuring NA as well as interventions that have been carried out to improve medication adherence and posttransplantation outcomes. Common risk factors for NA include low social support, medication-related factors (eg. side effects), regimen complexity, younger age, financial barriers, and low literacy. Additionally, we discuss special at-risk populations with pretransplantation substance abuse or psychiatric comorbidities as well as adolescents making a transition into adulthood and independent self-care. Multifaceted interventions that are personalized and specific to identified adherence barriers for high-risk groups seem to be the most promising approach to improve medication NA and posttransplantation outcomes. This review contains 4 figures, 5 tables, and 53 references Key Words: electronic monitoring, immunosuppression, liver transplantation, medication, nonadherence, noncompliance, tacrolimus standard deviation, transplantation outcomes


2004 ◽  
Vol 17 (3) ◽  
pp. 131-137 ◽  
Author(s):  
Josep Maria Castellvi ◽  
Xavier Xiol ◽  
Jordi Guardiola ◽  
Isabel Sabate ◽  
Manuel Roca ◽  
...  

2019 ◽  
Vol 70 (4) ◽  
pp. 658-665 ◽  
Author(s):  
Amelia J. Hessheimer ◽  
Elisabeth Coll ◽  
Ferrán Torres ◽  
Patricia Ruíz ◽  
Mikel Gastaca ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Eliza W. Beal ◽  
Dmitry Tumin ◽  
Lanla F. Conteh ◽  
A. James Hanje ◽  
Anthony J. Michaels ◽  
...  

There is a paucity of literature examining recipient-donor obesity matching on liver transplantation outcomes. The United Network for Organ Sharing database was queried for first-time recipients of liver transplant whose age was ≥18 between January 2003 and September 2013. Outcomes including patient and graft survival at 30 days, 1 year, and 5 years and overall, liver retransplantation, and length of stay were compared between nonobese recipients receiving a graft from nonobese donors and obese recipient-obese donor, obese recipient-nonobese donor, and nonobese recipient-obese donor pairs. 51,556 LT recipients were identified, including 34,217 (66%) nonobese and 17,339 (34%) obese recipients. The proportions of patients receiving an allograft from an obese donor were 24% and 29%, respectively, among nonobese and obese recipients. Graft loss (HR: 1.27; 95% CI: 1.09–1.46;p=0.002) and mortality (HR: 1.38; 95% CI: 1.16–1.65;p<0.001) at 30 days were increased in the obese recipient-obese donor pair. However, 1-year graft (HR: 0.83; 95% CI: 0.74–0.93;p=0.002) and patient (HR: 0.84; 95% CI: 0.74–0.95;p=0.007) survival and overall patient (HR: 0.93; 95% CI: 0.86–1.00;p=0.042) survival were favorable. There is evidence of recipient and donor obesity disadvantage early, but survival curves demonstrate improved long-term outcomes. It is important to consider obesity in the donor-recipient match.


2017 ◽  
Vol 32 (2) ◽  
pp. e13163 ◽  
Author(s):  
Anne Claire den Dulk ◽  
Xiaolei Shi ◽  
Cornelia. J. Verhoeven ◽  
Jeroen Dubbeld ◽  
Frans H. J. Claas ◽  
...  

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