scholarly journals Impact of the Pediatric End‐Stage Liver Disease ( PELD ) growth failure thresholds on mortality among pediatric liver transplant candidates

2019 ◽  
Vol 19 (12) ◽  
pp. 3308-3318 ◽  
Author(s):  
Sonja M. Swenson ◽  
John P. Roberts ◽  
Sue Rhee ◽  
Emily R. Perito
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Growth Failure ◽  
End Stage Liver Disease ◽  
Pediatric Liver ◽  
Transplant Candidates ◽  
End Stage ◽  
Pediatric Liver Transplant

scholarly journals Accuracy of the Pediatric End-stage Liver Disease Score in Estimating Pretransplant Mortality Among Pediatric Liver Transplant Candidates

2018 ◽  
Vol 172 (11) ◽  
pp. 1070 ◽  
Author(s):  
Chung-Chou H. Chang ◽  
Cindy L. Bryce ◽  
Benjamin L. Shneider ◽  
Jonathan G. Yabes ◽  
Yi Ren ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Disease Score ◽  
End Stage Liver Disease ◽  
Pediatric Liver ◽  
Transplant Candidates ◽  
End Stage ◽  
Pediatric Liver Transplant

scholarly journals High risk of delisting or death in liver transplant candidates following infections: Results from the North American consortium for the study of end-stage liver disease

2015 ◽  
Vol 21 (7) ◽  
pp. 881-888 ◽  
Author(s):  
K. Rajender Reddy ◽  
Jacqueline G. O'Leary ◽  
Patrick S. Kamath ◽  
Michael B. Fallon ◽  
Scott W. Biggins ◽  
...  
Keyword(s):  
Liver Disease ◽  
High Risk ◽  
Liver Transplant ◽  
North American ◽  
End Stage Liver Disease ◽  
The North ◽  
Transplant Candidates ◽  
End Stage

scholarly journals Under-Vaccination in Pediatric Liver Transplant Candidates with Acute and Chronic Liver Disease—A Retrospective Observational Study of the European Reference Network TransplantChild

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 675
Author(s):  
Tobias Laue ◽  
Zeynep Demir ◽  
Dominique Debray ◽  
Mara Cananzi ◽  
Paola Gaio ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Chronic Liver Disease ◽  
Vaccination Coverage ◽  
Chronic Liver ◽  
Control Group ◽  
Reference Network ◽  
Pediatric Liver ◽  
Transplant Candidates ◽  
Pediatric Liver Transplant

Infection is a serious concern in the short and long term after pediatric liver transplantation. Vaccination represents an easy and cheap opportunity to reduce morbidity and mortality due to vaccine-preventable infection. This retrospective, observational, multi-center study examines the immunization status in pediatric liver transplant candidates at the time of transplantation and compares it to a control group of children with acute liver disease. Findings show only 80% were vaccinated age-appropriately, defined as having received the recommended number of vaccination doses for their age prior to transplantation; for DTP-PV-Hib, less than 75% for Hepatitis B and two-thirds for pneumococcal conjugate vaccine in children with chronic liver disease. Vaccination coverage for live vaccines is better compared to the acute control group with 81% versus 62% for measles, mumps and rubella (p = 0.003) and 65% versus 55% for varicella (p = 0.171). Nevertheless, a country-specific comparison with national reference data suggests a lower vaccination coverage in children with chronic liver disease. Our study reveals an under-vaccination in this high-risk group prior to transplantation and underlines the need to improve vaccination.

scholarly journals Role of echocardiography in screening for portopulmonary hypertension in liver transplant candidates: a meta-analysis

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9243
Author(s):  
Xin Yin ◽  
Yueming Shao ◽  
Yu Zhang ◽  
Hui Gao ◽  
Tingting Qin ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Likelihood Ratio ◽  
Meta Analysis ◽  
Positive Likelihood Ratio ◽  
Cochrane Library ◽  
Portopulmonary Hypertension ◽  
End Stage Liver Disease ◽  
Transplant Candidates ◽  
End Stage

Objectives To demonstrate the screening value of echocardiography for portopulmonary hypertension (POPH) in liver transplant candidates. Design Systematic review and meta-analysis. Background POPH is a complication of end-stage liver disease that adversely affects the outcome of orthotopic liver transplant. There are no specific symptoms in the early stage of POPH. POPH reduce the survival rate of patients with end-stage liver disease specially if they are not diagnosed. Therefore, early detection may improve prognosis. The objective of this study is to explore the screening value of echocardiography on liver transplant candidates for screening of POPH compared to right heart catheterization (RHC). Method PubMed, EMBASE and the Cochrane Library were searched by two independent reviewers for potentially eligible studies published up to 30 June 2019 to retrieve data based on per-patient analysis. STATA, Meta-DiSc, and RevMan were applied to perform this meta-analysis. Results Our search yielded 1576 studies, of which 11 satisfied the inclusion criteria. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR) and area under the summary receiver operating characteristic (SROC) curve (AUC) of echocardiography for POPH were 0.85 (95% CI [0.65–0.94]), 0.83 (95% CI [0.73–0.90]), 4.99 (95% CI [3.03–8.21]), 0.19 (95% CI [0.07–0.46]), and 0.91 (95% CI [0.88–0.93]), respectively. Deeks’ funnel plot did not indicate the existence of publication bias (P = 0.66). Conclusions Echocardiography, a noninvasive modality, provides superior screening for POPH, but the diagnosis of POPH still requires RHC. PROSPERO registration number CRD42019144589.

scholarly journals Outcomes for liver transplant candidates listed with low model for end-stage liver disease score

2015 ◽  
Vol 21 (11) ◽  
pp. 1403-1409 ◽  
Author(s):  
Allison J. Kwong ◽  
Jennifer C. Lai ◽  
Jennifer L. Dodge ◽  
John P. Roberts
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Disease Score ◽  
End Stage Liver Disease ◽  
Transplant Candidates ◽  
End Stage

Liver simulated allocation model does not effectively predict organ offer decisions for pediatric liver transplant candidates

2021 ◽  
Author(s):  
Nicholas L. Wood ◽  
Douglas B. Mogul ◽  
Emily R. Perito ◽  
Douglas VanDerwerken ◽  
George V. Mazariegos ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Allocation Model ◽  
Pediatric Liver ◽  
Transplant Candidates ◽  
Pediatric Liver Transplant
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