scholarly journals Anti-Leukocyte Function-Associated Antigen 1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade-Resistant Rejection

2016 ◽  
Vol 16 (5) ◽  
pp. 1456-1464 ◽  
Author(s):  
D. J. Anderson ◽  
D. J. Lo ◽  
F. Leopardi ◽  
M. Song ◽  
N. A. Turgeon ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Nonhuman Primate ◽  
Costimulation Blockade ◽  
Leukocyte Function ◽  
Transplant Model

scholarly journals Secondary lymphoid tissue and costimulation‐blockade resistant rejection: A nonhuman primate renal transplant study

2019 ◽  
Vol 19 (8) ◽  
pp. 2350-2357 ◽  
Author(s):  
Michael S. Mulvihill ◽  
Kannan P. Samy ◽  
Qimeng A. Gao ◽  
Robin Schmitz ◽  
Robert P. Davis ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Nonhuman Primate ◽  
Lymphoid Tissue ◽  
Costimulation Blockade ◽  
Secondary Lymphoid Tissue

scholarly journals Translational impact of NIH-funded nonhuman primate research in transplantation

2019 ◽  
Vol 11 (500) ◽  
pp. eaau0143 ◽  
Author(s):  
Stuart J. Knechtle ◽  
Julia M. Shaw ◽  
Bernhard J. Hering ◽  
Kristy Kraemer ◽  
Joren C. Madsen
Keyword(s):  
Clinical Trials ◽  
Cell Therapy ◽  
Immune Responses ◽  
Nonhuman Primate ◽  
Immune Cell ◽  
National Institutes Of Health ◽  
Primate Research ◽  
Costimulation Blockade ◽  
Hematopoietic Chimerism ◽  
New Treatments

The National Institutes of Health (NIH) has long supported using nonhuman primate (NHP) models for research on kidney, pancreatic islet, heart, and lung transplantation. The primary purpose of this research has been to develop new treatments for down-modulating or preventing deleterious immune responses after transplantation in human patients. Here, we discuss NIH-funded NHP studies of immune cell depletion, costimulation blockade, regulatory cell therapy, desensitization, and mixed hematopoietic chimerism that either preceded clinical trials or prevented the human application of therapies that were toxic or ineffective.

THE RHESUS MONKEY AS A RENAL TRANSPLANT MODEL

1969 ◽  
Vol 162 (1 Experimental) ◽  
pp. 419-428 ◽  
Author(s):  
Gerald P. Murphy ◽  
Gerald S. Johnston ◽  
Edwin A. Mirand ◽  
Edward Melby ◽  
William W. Scott
Keyword(s):  
Renal Transplant ◽  
Rhesus Monkey ◽  
Transplant Model

scholarly journals Efficacy of Oral Treatment With Tacrolimus in the Renal Transplant Model in Cynomolgus Monkeys

2008 ◽  
Vol 108 (4) ◽  
pp. 529-534 ◽  
Author(s):  
Fumitaka Kinugasa ◽  
Itsuo Nagatomi ◽  
Hirofumi Ishikawa ◽  
Tomonori Nakanishi ◽  
Masashi Maeda ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Oral Treatment ◽  
Cynomolgus Monkeys ◽  
Transplant Model
Sign in / Sign up

Export Citation Format

Share Document