scholarly journals Th17 cell inhibition in a costimulation blockade‐based regimen for vascularized composite allotransplantation using a nonhuman primate model

2020 ◽  
Vol 33 (10) ◽  
pp. 1294-1301 ◽  
Author(s):  
Andrew Atia ◽  
Dimitrios Moris ◽  
MacKenzie McRae ◽  
Mingqing Song ◽  
Linda Stempora ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Th17 Cell ◽  
Vascularized Composite Allotransplantation ◽  
Costimulation Blockade ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
Cell Inhibition

Regulatory T Cells Are Not Predictive of Outcomes in a Nonhuman Primate Model of Vascularized Composite Allotransplantation

2013 ◽  
Vol 96 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Philip S. Brazio ◽  
Raghava B. Munivenkatappa ◽  
Branko Bojovic ◽  
Jinny S. Ha ◽  
Emile N. Brown ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Nonhuman Primate ◽  
Vascularized Composite Allotransplantation ◽  
Nonhuman Primate Model ◽  
Primate Model

Histopathology of Chronic Rejection in a Nonhuman Primate Model of Vascularized Composite Allotransplantation

2013 ◽  
Vol 95 (10) ◽  
pp. 1204-1210 ◽  
Author(s):  
Gerhard S. Mundinger ◽  
Raghava Munivenkatappa ◽  
Cinthia B. Drachenberg ◽  
Jinny S. Ha ◽  
Elbert E. Vaca ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Chronic Rejection ◽  
Vascularized Composite Allotransplantation ◽  
Nonhuman Primate Model ◽  
Primate Model

Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 222-OR
Author(s):  
MICHAEL J. NASH ◽  
TAYLOR K. SODERBORG ◽  
RACHEL C. JANSSEN ◽  
ERIC M. PIETRAS ◽  
JACOB E. FRIEDMAN
Keyword(s):  
Bone Marrow ◽  
Nonhuman Primate ◽  
High Fat Diet ◽  
Immune Cell ◽  
High Fat ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
And Function

scholarly journals Reperfusion plus Selective Intra-arterial Cooling (SI-AC) Improve Recovery in a Nonhuman Primate Model of Stroke

2020 ◽  
Author(s):  
Di Wu ◽  
Yongjuan Fu ◽  
Longfei Wu ◽  
Mitchell Huber ◽  
Jian Chen ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Nonhuman Primate Model ◽  
Primate Model

Robotic Assessment of Upper Limb Function in a Nonhuman Primate Model of Chronic Stroke

2021 ◽  
Author(s):  
Yining Chen ◽  
Meredith C. Poole ◽  
Shelby V. Olesovsky ◽  
Allen A. Champagne ◽  
Kathleen A. Harrison ◽  
...  
Keyword(s):  
Upper Limb ◽  
Nonhuman Primate ◽  
Chronic Stroke ◽  
Nonhuman Primate Model ◽  
Limb Function ◽  
Primate Model ◽  
Upper Limb Function

scholarly journals Transcriptomic phases of periodontitis lesions using the nonhuman primate model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jeffrey L. Ebersole ◽  
Radhakrishnan Nagarajan ◽  
Sreenatha Kirakodu ◽  
Octavio A. Gonzalez
Keyword(s):  
Gene Expression ◽  
Nonhuman Primate ◽  
Gingival Crevicular Fluid ◽  
Inflammatory Responses ◽  
Expression Profiles ◽  
Lesion Detection ◽  
Gingival Tissue ◽  
Specific Gene ◽  
Nonhuman Primate Model ◽  
Primate Model

AbstractWe used a nonhuman primate model of ligature-induced periodontitis to identify patterns of gingival transcriptomic after changes demarcating phases of periodontitis lesions (initiation, progression, resolution). A total of 18 adult Macaca mulatta (12–22 years) had ligatures placed (premolar, 1st molar teeth) in all 4 quadrants. Gingival tissue samples were obtained (baseline, 2 weeks, 1 and 3 months during periodontitis and at 5 months resolution). Gene expression was analyzed by microarray [Rhesus Gene 1.0 ST Array (Affymetrix)]. Compared to baseline, a large array of genes were significantly altered at initiation (n = 6049), early progression (n = 4893), and late progression (n = 5078) of disease, with the preponderance being up-regulated. Additionally, 1918 genes were altered in expression with disease resolution, skewed towards down-regulation. Assessment of the genes demonstrated specific profiles of epithelial, bone/connective tissue, apoptosis/autophagy, metabolism, regulatory, immune, and inflammatory responses that were related to health, stages of disease, and tissues with resolved lesions. Unique transcriptomic profiles occured during the kinetics of the periodontitis lesion exacerbation and remission. We delineated phase specific gene expression profiles of the disease lesion. Detection of these gene products in gingival crevicular fluid samples from human disease may contribute to a better understanding of the biological dynamics of the disease to improve patient management.

scholarly journals Point‐of‐Care Assessment of DCD Livers During Normothermic Machine Perfusion in a Nonhuman Primate Model

2021 ◽  
Author(s):  
Samuel J. Kesseli ◽  
Jared N. Gloria ◽  
Nader Abraham ◽  
Samantha E. Halpern ◽  
Greta N. Cywinska ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Point Of Care ◽  
Machine Perfusion ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
Care Assessment ◽  
Normothermic Machine Perfusion
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