scholarly journals Hypothermic Machine Preservation Facilitates Successful Transplantation of “Orphan” Extended Criteria Donor Livers

2014 ◽  
Vol 15 (1) ◽  
pp. 161-169 ◽  
Author(s):  
J. V. Guarrera ◽  
S. D. Henry ◽  
B. Samstein ◽  
E. Reznik ◽  
C. Musat ◽  
...  
Keyword(s):  
Extended Criteria Donor ◽  
Successful Transplantation ◽  
Hypothermic Machine Preservation

Hypothermic Machine Preservation and Transplantation of “Orphan” Extended Criteria Donor Livers.

2014 ◽  
Vol 98 ◽  
pp. 175 ◽  
Author(s):  
J. Guarrera ◽  
S. Henry ◽  
B. Samstein ◽  
L. Reznik ◽  
C. Musat ◽  
...  
Keyword(s):  
Extended Criteria Donor ◽  
Hypothermic Machine Preservation

scholarly journals Epidemiology, Risk Factors, and Outcomes of Opportunistic Infections after Kidney Allograft Transplantation in the Era of Modern Immunosuppression: A Monocentric Cohort Study

2019 ◽  
Vol 8 (5) ◽  
pp. 594 ◽  
Author(s):  
Philippe Attias ◽  
Giovanna Melica ◽  
David Boutboul ◽  
Nathalie De Castro ◽  
Vincent Audard ◽  
...  
Keyword(s):  
Risk Factors ◽  
Protective Factor ◽  
Opportunistic Infections ◽  
Control Group ◽  
Kidney Allograft ◽  
Extended Criteria Donor ◽  
Allograft Transplantation ◽  
Kidney Recipients ◽  
Independent Risk Factors ◽  
Kidney Transplantations

Epidemiology of opportunistic infections (OI) after kidney allograft transplantation in the modern era of immunosuppression and the use of OI prevention strategies are poorly described. We retrospectively analyzed a single-center cohort on kidney allograft adult recipients transplanted between January 2008 and December 2013. The control group included all kidney recipients transplanted in the same period, but with no OI. We analyzed 538 kidney transplantations (538 patients). The proportion of OI was 15% (80 and 72 patients). OI occurred 12.8 (6.0–31.2) months after transplantation. Viruses were the leading cause (n = 54, (10%)), followed by fungal (n = 15 (3%)), parasitic (n = 6 (1%)), and bacterial (n = 5 (0.9%)) infections. Independent risk factors for OI were extended criteria donor (2.53 (1.48–4.31), p = 0.0007) and BK viremia (6.38 (3.62–11.23), p < 0.0001). High blood lymphocyte count at the time of transplantation was an independent protective factor (0.60 (0.38–0.94), p = 0.026). OI was an independent risk factor for allograft loss (2.53 (1.29–4.95), p = 0.007) but not for patient survival. Post-kidney transplantation OIs were mostly viral and occurred beyond one year after transplantation. Pre-transplantation lymphopenia and extended criteria donor are independent risk factors for OI, unlike induction therapy, hence the need to adjust immunosuppressive regimens to such transplant candidates.

Use of Extended Criteria Donor Hearts in Simultaneous Heart-Kidney Transplantation

2021 ◽  
Vol 40 (4) ◽  
pp. S113
Author(s):  
M.R. Helmers ◽  
P. Altshuler ◽  
M. Shin ◽  
A. Iyengar ◽  
D. Herbst ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Extended Criteria Donor

scholarly journals Successful transplantation of organs from a deceased donor with early SARS‐CoV‐2 infection

2021 ◽  
Author(s):  
Abhay Dhand ◽  
Alan Gass ◽  
Seigo Nishida ◽  
Masashi Kai ◽  
Karen Berger ◽  
...  
Keyword(s):  
Deceased Donor ◽  
Successful Transplantation

scholarly journals Ethical and Legal Implications of Elective Ventilation and Organ Transplantation: “Medicalization” of Dying versus Medical Mission

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Paola Frati ◽  
Vittorio Fineschi ◽  
Matteo Gulino ◽  
Gianluca Montanari Vergallo ◽  
Natale Mario Di Luca ◽  
...  
Keyword(s):  
Organ Donation ◽  
Organ Donor ◽  
Legal Framework ◽  
Organ Donors ◽  
Organ Perfusion ◽  
Medical Mission ◽  
Legal Implications ◽  
Legal Context ◽  
Successful Transplantation ◽  
Italian Context

A critical controversy surrounds the type of allowable interventions to be carried out in patients who are potential organ donors, in an attempt to improve organ perfusion and successful transplantation. The main goal is to transplant an organ in conditions as close as possible to its physiological live state. “Elective ventilation” (EV), that is, the use of ventilation for the sole purpose of retrieving the organs of patients close to death, is an option which offsets the shortage of organ donation. We have analyzed the legal context of the dying process of the organ donor and the feasibility of EV in the Italian context. There is no legal framework regulating the practice of EV, neither is any real information given to the general public. A public debate has yet to be initiated. In the Italian cultural and legislative scenario, we believe that, under some circumstances (i.e., the expressed wishes of the patient, even in the form of advance directives), the use of EV does not violate the principle of beneficence. We believe that the crux of the matter lies in the need to explore the real determination and will of the patient and his/her orientation towards the specific aim of organ donation.

SUCCESSFUL TRANSPLANTATION OF NEONATAL RAT ISLET TISSUE PRESERVED FOR UP TO 63 HOURS

ASAIO Journal ◽  
1977 ◽  
Vol 23 (1) ◽  
pp. 347-350 ◽  
Author(s):  
A. J. Matas ◽  
D. E. R. Sutherland ◽  
W. D. Payne ◽  
J. Grotting ◽  
M. W. Steffes ◽  
...  
Keyword(s):  
Neonatal Rat ◽  
Islet Tissue ◽  
Successful Transplantation

SUCCESSFUL TRANSPLANTATION OF BLOOD GROUP A2 KIDNEYS INTO NON-A RECIPIENTS

1988 ◽  
Vol 45 (2) ◽  
pp. 316-319 ◽  
Author(s):  
Paul W. Nelson ◽  
Thomas S. Helling ◽  
George E. Pierce ◽  
Gilbert Ross ◽  
Charles F. Shield ◽  
...  
Keyword(s):  
Blood Group ◽  
Successful Transplantation

scholarly journals 26-hour Storage of a Declined Liver Before Successful Transplantation Using Ex Vivo Normothermic Perfusion

2017 ◽  
Vol 265 (1) ◽  
pp. e1-e2 ◽  
Author(s):  
Christopher J. E. Watson ◽  
Lucy V. Randle ◽  
Vasilis Kosmoliaptsis ◽  
Paul Gibbs ◽  
Michael Allison ◽  
...  
Keyword(s):  
Ex Vivo ◽  
Normothermic Perfusion ◽  
Successful Transplantation

The Transplantation of Individual Rat and Guinea-pig Whisker Papillae

Development ◽  
1961 ◽  
Vol 9 (1) ◽  
pp. 117-127
Author(s):  
J. Cohen
Keyword(s):  
Guinea Pig ◽  
Dermal Papilla ◽  
Successful Transplantation ◽  
Hair Development

Previous work on the pigmentation and transplantation of hair and skin has been performed mainly on gross skin areas (e.g. Billingham & Medawar, 1950; Ebling & Johnson, 1959; Rawles, 1955) and several studies have been concerned with the histological appearances of various stages in hair development, sometimes correlated with the effects of chemical or physical agents (e.g. Chase, 1955; Chase, Rauch & Smith, 1951). So far there have been no reports of successful transplantation of individual hair papillae, although several authors have considered this to be a possibility (e.g. Billingham, 1958). Lillie & Wang (1941, 1944) showed that a feather papilla may produce generations of feathers after transplantation to another follicle, and that the feathers produced from a transplanted papilla containing both dermal and epidermal components (‘whole papilla’) are of donor tract structure and colour; feathers produced from local ectoderm under the influence of a transplanted dermal papilla are of host tract structure and colour.

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