scholarly journals Successful transplantation of organs from a deceased donor with early SARS‐CoV‐2 infection

2021 ◽  
Author(s):  
Abhay Dhand ◽  
Alan Gass ◽  
Seigo Nishida ◽  
Masashi Kai ◽  
Karen Berger ◽  
...  
Keyword(s):  
Deceased Donor ◽  
Successful Transplantation

scholarly journals Segmental Renal Ischemia following Transplantation of Horseshoe Kidney as Separate Allografts

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
J. T. Foster ◽  
P. E. Morrissey
Keyword(s):  
End Stage Renal Disease ◽  
Case Reports ◽  
Graft Function ◽  
Horseshoe Kidney ◽  
Deceased Donor ◽  
Successful Transplantation ◽  
Mere Presence ◽  
Technical Complication ◽  
Stage Renal Disease ◽  
End Stage

Introduction. Horseshoe kidney is a congenital anomaly that presents unique challenges for the transplant surgeon. The mere presence of horseshoe kidney should not preclude consideration for transplantation.Case Report. A 33-year-old women suffering from end-stage renal disease underwent deceased donor renal transplant with a divided horseshoe kidney. We present a postoperative complication and the technical strategy for transplant salvage. The patient currently has excellent graft function.Discussion. Horseshoe kidneys do present challenges for successful transplantation. Though case reports of successful transplantation are increasing, we present a technical complication and successful transplant salvage strategy. Technical descriptions in the literature of successful back-table preparation strategies should help more transplant surgeons to begin to utilize this resource.Conclusion. This study concludes that horseshoe kidneys can be successfully used for transplantation and provides a technical strategy to salvage the transplant after a unique complication associated with these donor kidneys.

scholarly journals Successful Transplantation of a Split Crossed Fused Ectopic Kidney into a Patient with End-Stage Renal Disease

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Kristin L. Mekeel ◽  
Shane M. Daley ◽  
Paul E. Andrews ◽  
Adyr A. Moss ◽  
R. L. Heilman ◽  
...  
Keyword(s):  
Deceased Donor ◽  
Technical Difficulty ◽  
Parenchymal Transection ◽  
Ectopic Kidney ◽  
Renal Anomalies ◽  
Successful Transplantation ◽  
Immediate Function ◽  
Deceased Donor Kidney Transplant ◽  
Stage Renal Disease ◽  
End Stage

Potential donors with congenital renal anomalies but normal renal function are often overlooked because of a possible increase in technical difficulty and complications associated with the surgery. However, as the waiting list for a deceased donor kidney transplant continues to grow, it is important to consider these kidneys for potential transplant. This paper describes the procurement of a crossed fused ectopic kidney, and subsequent parenchymal transection prior to transplantation as part of a combined simultaneous kidney pancreas transplant. The transplant was uncomplicated, and the graft had immediate function. The patient is now two years from transplant with excellent function.

scholarly journals Trends in Discard of Kidneys from Hepatitis C Viremic Donors in the United States

2021 ◽  
Vol 16 (2) ◽  
pp. 251-261 ◽  
Author(s):  
Su-Hsin Chang ◽  
Massini Merzkani ◽  
Krista L. Lentine ◽  
Mei Wang ◽  
David A. Axelrod ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Organ Procurement ◽  
Deceased Donor ◽  
The United States ◽  
Nucleic Acid Amplification ◽  
Direct Acting Antiviral ◽  
Successful Transplantation ◽  
Organ Procurement Organizations ◽  
Hcv Antibody ◽  
Direct Acting

Background and objectivesKidneys from hepatitis C virus (HCV) viremic donors have become more commonly accepted for transplant, especially after effective direct-acting antiviral therapy became available in 2014. We examined the contemporary trend of kidney discard from donors with HCV seropositivity and viremia.Design, setting, participants, & measurementsData from the Organ Procurement and Transplantation Network were used to identify deceased donor kidneys recovered for transplant. The exposure was donor HCV antibody status in the first analyses, and donor HCV antibody and viremia status in the second analyses. Multilevel, multivariable logistic regression was used to assess the association of these HCV exposure measures with kidney discard, adjusted for donor characteristics. Multilevel analyses were conducted to account for similar kidney discard pattern within clusters of organ procurement organizations and regions.ResultsAmong 225,479 kidneys recovered from 2005 to 2019, 5% were from HCV seropositive donors. Compared with HCV seronegative kidneys, the odds of HCV seropositive kidney discard gradually declined, from a multivariable-adjusted odds ratio (aOR) of 7.06 (95% confidence interval [95% CI], 5.65 to 8.81) in 2014, to 1.20 (95% CI, 1.02 to 1.42) in 2019. Among 82,090 kidneys with nucleic acid amplification test results in 2015–2019, 4% were from HCV viremic donors and 2% were from aviremic seropositive donors. Compared with HCV aviremic seronegative kidneys, the odds of HCV viremic kidney discard decreased from an aOR of 4.89 (95% CI, 4.03 to 5.92) in 2018, to 1.48 (95% CI, 1.22 to 1.81) in 2019. By 2018 and 2019, aviremic seropositive status was not associated with higher odds of discard (2018: aOR, 1.13; 95% CI, 0.88 to 1.45; and 2019: aOR, 0.97; 95% CI, 0.76 to 1.23).ConclusionsDespite the decrease in kidney discard in recent years, kidneys from viremic (compared with aviremic seronegative) donors still had 48% higher odds of discard in 2019. The potential of these discarded organs to provide successful transplantation should be explored.

Experiencing Kidney Transplant from Deceased Donor in the Family

2013 ◽  
Author(s):  
Maria Goreti da Silva Cruz ◽  
Ana Lucia de Moraes Horta ◽  
Rosa Maria Macedo
Keyword(s):  
Kidney Transplant ◽  
Deceased Donor ◽  
The Family

scholarly journals Prediction model for early graft failure after liver transplantation using aspartate aminotransferase, total bilirubin and coagulation factor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jinsoo Rhu ◽  
Jong Man Kim ◽  
Kyunga Kim ◽  
Heejin Yoo ◽  
Gyu-Seong Choi ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prediction Model ◽  
Aspartate Aminotransferase ◽  
Graft Failure ◽  
Living Donor ◽  
Total Bilirubin ◽  
Deceased Donor ◽  
Time Dependent ◽  
Early Graft ◽  
Early Graft Failure

AbstractThis study was designed to build models predicting early graft failure after liver transplantation. Cox regression model for predicting early graft failure after liver transplantation using post-transplantation aspartate aminotransferase, total bilirubin, and international normalized ratio of prothrombin time was constructed based on data from both living donor (n = 1153) and deceased donor (n = 359) liver transplantation performed during 2004 to 2018. The model was compared with Model for Early Allograft Function Scoring (MEAF) and early allograft dysfunction (EAD) with their C-index and time-dependent area-under-curve (AUC). The C-index of the model for living donor (0.73, CI = 0.67–0.79) was significantly higher compared to those of both MEAF (0.69, P = 0.03) and EAD (0.66, P = 0.001) while C-index for deceased donor (0.74, CI = 0.65–0.83) was only significantly higher compared to C-index of EAD. (0.66, P = 0.002) Time-dependent AUC at 2 weeks of living donor (0.96, CI = 0.91–1.00) and deceased donor (0.98, CI = 0.96–1.00) were significantly higher compared to those of EAD. (both 0.83, P < 0.001 for living donor and deceased donor) Time-dependent AUC at 4 weeks of living donor (0.93, CI = 0.86–0.99) was significantly higher compared to those of both MEAF (0.87, P = 0.02) and EAD. (0.84, P = 0.02) Time-dependent AUC at 4 weeks of deceased donor (0.94, CI = 0.89–1.00) was significantly higher compared to both MEAF (0.82, P = 0.02) and EAD. (0.81, P < 0.001). The prediction model for early graft failure after liver transplantation showed high predictability and validity with higher predictability compared to traditional models for both living donor and deceased donor liver transplantation.

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