Does aspirin prescribed to women deemed high risk for preterm pre‐eclampsia at 11–13 +6 weeks gestation affect the prevalence of small for gestational age neonates?

2020 ◽  
Author(s):  
Felicity Park ◽  
Cecelia O’Brien ◽  
Jason Phung ◽  
Theophilus Emeto ◽  
Jon Hyett
Keyword(s):  
High Risk ◽  
Gestational Age ◽  
Small For Gestational Age

Prediction of Preeclampsia and Delivery of Small for Gestational Age Babies Based on a Combination of Clinical Risk Factors in High-Risk Women

2010 ◽  
Vol 30 (1) ◽  
pp. 58-73 ◽  
Author(s):  
Paul T. Seed ◽  
Lucy C. Chappell ◽  
Michael A. Black ◽  
Katrina K. Poppe ◽  
Yuan-Chun Hwang ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Clinical Risk Factors ◽  
High Risk Women ◽  
Clinical Risk

scholarly journals Conception via Assisted Reproductive Techniques: an Independent Risk Factor for Poor Perinatal Outcome

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
High Risk ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Post Partum ◽  
Assisted Reproductive Techniques ◽  
Reproductive Techniques ◽  
Post Partum Haemorrhage

Assisted Reproductive Techniques (ART) are well established treatments offered in the sub-fertile couple. As a consequence, obstetricians increasingly have to manage high risk pregnancies without any formal guidelines to follow. We carried out a retrospective cohort study to evaluate the risks of ART using data from 11875 women (11326 spontaneously conceived pregnancies and 549 using ART) in order to propose a policy to better manage them antenatally. Outcome measures included induction of labour, method of and gestation at delivery, gestational diabetes mellitus, and small for gestational age, anal sphincter injury, post-partum haemorrhage and neonatal morbidity and mortality. The ART group had higher rates of gestational diabetes mellitus (18.9% vs 9.4%, P <0.0001), small for gestational age (9.1% vs 5.6%, P=0.001), instrumental delivery (19.6 vs 11.8%, P<0.0001), emergency caesarean section (26.8% vs 15%, P<0.0001) and post-partum haemorrhage >1500mL (6.9% vs 3%, P<0.0001). Lower Apgar scores (2.6% vs 1.4%, P=0.03) and admission to neonatal unit were more likely in the ART group (10.2% vs 5.4%, P<0.0001). Our results suggest that antenatal monitoring for gestational diabetes mellitus and fetal growth, appropriate counselling regarding mode and timing of delivery and active management of 3rd stage of labour, are essential when managing high risk ART pregnancies.

scholarly journals Early Clinical Infancy Outcomes for Microcephaly and/or Small for Gestational Age Zika-Exposed Infants

2019 ◽  
Vol 70 (12) ◽  
pp. 2663-2672 ◽  
Author(s):  
Kristina Adachi ◽  
Tahmineh Romero ◽  
Karin Nielsen-Saines ◽  
Sheila Pone ◽  
Mitsue Aibe ◽  
...  
Keyword(s):  
High Risk ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Growth Parameters ◽  
Adverse Outcomes ◽  
Growth Trajectories ◽  
First Year ◽  
Z Score ◽  
Infant Outcomes ◽  
First Year Of Life

Abstract Background Zika-exposed infants with microcephaly (proportional or disproportional) and those who are small for gestational age without microcephaly should be closely followed, particularly their growth trajectories. They are at high risk of adverse outcomes in the first year of life. Antenatal Zika virus (ZIKV) exposure may lead to adverse infant outcomes including microcephaly and being small for gestational age (SGA). ZIKV-exposed infants with a diagnosis of microcephaly (proportional [PM] or disproportional [DM]) or SGA at birth were evaluated with anthropometric measurements and health outcomes. Methods Infants had laboratory-confirmed ZIKV exposure in Brazil. PM, DM, or SGA classification was based on head circumference and weight. First-year growth parameters and clinical outcomes were recorded with analyses performed. Results Among the 156 ZIKV-exposed infants, 14 (9.0%) were SGA, 13 (8.3%) PM, 13 (8.3%) DM, and 116 (74.4%) were neither SGA nor had microcephaly (NSNM). High rates of any neurologic, ophthalmologic, and hearing abnormalities were observed for PM (100%), DM (100%), and SGA (42.9%) vs NSNM infants (18.3%; P &lt;.001); odds ratio [OR], 3.4 (95% confidence interval [CI], 1.1–10.7) for SGA vs NSNM. Neuroimaging abnormalities were seen in 100% of PM and DM and in 42.9% of SGA vs NSNM infants 16%; (P &lt;.001); OR 3.9 (95% CI, 1.2–12.8) for SGA vs NSNM. Growth rates by z score, particularly for microcephaly infants, were poor after birth but showed improvement beyond 4 months of life. Conclusions ZIKV-exposed infants with microcephaly (PM and DM) had similarly high rates of adverse outcomes but showed improvement in growth measurements beyond 4 months of life. While SGA infants had fewer adverse outcomes compared with microcephaly infants, notable adverse outcomes were observed in some; their odds of having adverse outcomes were 3 to 4 times greater compared to NSNM infants. Zika-exposed infants with microcephaly, irrespective of being proportional or disproportional, and those who are small for gestational age without microcephaly should be closely followed, particularly their growth trajectories. They are at high risk of adverse outcomes in the first year of life.

The limits of small-for-gestational-age as a high-risk category

2021 ◽  
Author(s):  
Allen J. Wilcox ◽  
Marianna Cortese ◽  
D. Robert McConnaughey ◽  
Dag Moster ◽  
Olga Basso
Keyword(s):  
High Risk ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Risk Category ◽  
High Risk Category
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