scholarly journals High Risk of Sensorineural Hearing Loss in Men Born Small for Gestational Age with and without Obesity or Height Catch-Up Growth: A Prospective Longitudinal Register Study on Birth Size in 245,000 Swedish Conscripts

2005 ◽  
Vol 90 (8) ◽  
pp. 4452-4456 ◽  
Author(s):  
Marie-Louise Barrenäs ◽  
Björn Jonsson ◽  
Torsten Tuvemo ◽  
Per-Anders Hellström ◽  
Maria Lundgren
2019 ◽  
Vol 162 (1) ◽  
pp. 129-136 ◽  
Author(s):  
Evette A. Ronner ◽  
Liliya Benchetrit ◽  
Patricia Levesque ◽  
Razan A. Basonbul ◽  
Michael S. Cohen

Objective To assess quality of life (QOL) in pediatric patients with sensorineural hearing loss (SNHL) with the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) and the Hearing Environments and Reflection on Quality of Life 26 (HEAR-QL-26) and HEAR-QL-28 surveys. Study Design Prospective longitudinal study. Setting Tertiary care center. Subjects and Methods Surveys were administered to patients with SNHL (ages 2-18 years) from July 2016 to December 2018 at a multidisciplinary hearing loss clinic. Patients aged >7 years completed the HEAR-QL-26, HEAR-QL-28, and PedsQL 4.0 self-report tool, while parents completed the PedsQL 4.0 parent proxy report for children aged ≤7 years. Previously published data from children with normal hearing were used for controls. The independent t test was used for analysis. Results In our cohort of 100 patients, the mean age was 7.7 years (SD, 4.5): 62 participants had bilateral SNHL; 63 had mild to moderate SNHL; and 37 had severe to profound SNHL. Sixty-eight patients used a hearing device. Mean (SD) total survey scores for the PedsQL 4.0 (ages 2-7 and 8-18 years), HEAR-QL-26 (ages 7-12 years), and HEAR-QL-28 (ages 13-18 years) were 83.9 (14.0), 79.2 (11.1), 81.2 (9.8), and 77.5 (11.3), respectively. Mean QOL scores for patients with SNHL were significantly lower than those for controls on the basis of previously published normative data ( P < .0001). There was no significant difference in QOL between children with unilateral and bilateral SNHL or between children with SNHL who did and did not require a hearing device. Low statistical power due to small subgroup sizes limited our analysis. Conclusion It is feasible to collect QOL data from children with SNHL in a hearing loss clinic. Children with SNHL had significantly lower scores on validated QOL instruments when compared with peers with normal hearing.


Author(s):  
J. Ramanjaneyulu ◽  
S. Rajesh Kumar ◽  
V. Krishna Chaitanya ◽  
A. Kusumanjali

<p><strong>Background: </strong>Early identification of congenital hearing loss and early intervention ameliorated many adverse consequences. This study was performed to observe effectiveness of otoacoustic emission in screening of hearing loss in high-risk babies.</p><p><strong>Methods: </strong>Prospective study on 45 high-risk newborns delivered during period of 2013-2014. Selective newborn hearing performed with oto acoustic emissions (OAE) and auditory brain stem responses (ABR), in high-risk infants aged below 7 days, 15 days, after 45 days and after 90 days.</p><p><strong>Results: </strong>Study population comprised of 45 high-risk newborns. In 1<sup>st</sup> level screening, 28 (62%) babies showed recordable OAE, 17 (38%) babies failed. In 2<sup>nd</sup> level screening 31 (81%) passed and 7 (19%) failed and death occurred in 7 infants. In 3<sup>rd</sup> level screening both OAE and brain stem evoked response audiometry (BERA), was performed in 38 cases and positivity was reported in 37 cases. 4<sup>th</sup> level screening was similar to 3<sup>rd</sup> level screening where 3 babies failed ABR test. In our study incidence of sensorineural hearing loss found to be 78.91% (3/38×1000) per 1000 high-risk babies. Auditory neuropathy was observed in 2 (4.4%) patients. Sensitivity and specificity of OAE was 100% and 33.3% respectively. In high-risk low birth weight neonates’ sensitivity and specificity was 66.7% and 50.0%.</p><p><strong>Conclusions: </strong>In high-risk babies, appropriate time for screening with OAE is around 60 days of age. OAE are useful diagnostic tool in evaluation of high-risk neonates for early detection of sensorineural hearing loss.</p>


2017 ◽  
Vol 126 (5) ◽  
pp. 382-387 ◽  
Author(s):  
Young-Soo Chang ◽  
Ji Eun Choi ◽  
Jungmin Ahn ◽  
Nam-Gyu Ryu ◽  
Il Joon Moon ◽  
...  

Objectives/Hypothesis: Predicting the prognosis of idiopathic sudden sensorineural hearing loss (ISSHL) remains challenging. This investigation aimed to apply Framingham Risk Scores (FRS) to assess the combination of prognostic factors following ISSHL and investigate the predictive role of FRS in patients with multiple comorbidities including hypertension, diabetes, and hyperlipidemia. Study design: Retrospective study. Methods: Twenty-one patients presenting with unilateral idiopathic sudden sensorineural hearing loss and multiple comorbidities were surveyed. Framingham Risk Score was calculated, and patients were assigned into high-risk (FRS ≥20%) and low-risk (FRS <20%) groups. Mean pure tone audiometry (PTA) threshold of both groups and hearing outcomes following established criteria were investigated. All patients were treated with the same protocol of oral methylprednisolone. Results: Overall successful recovery rate (complete + marked recovery) was 23.81%. The mean PTA threshold of the low-risk group showed significant improvement (mean PTA ± standard error, SE: pretreatment, 73.23 ± 11.80; posttreatment, 54.89 ± 10.25, P = .002), while the high-risk group did not show significant improvement in mean PTA threshold (mean PTA ± SE: pretreatment, 71.94 ± 11.77; posttreatment, 68.89 ± 12.81, P = .73). Conclusion: Framingham Risk Scores may be useful in predicting outcomes for ISSHL patients with multiple comorbidities.


1986 ◽  
Vol 89 (2) ◽  
pp. 135-141
Author(s):  
NORIKO NISHIZAWA ◽  
TOSHIKI MANABE ◽  
SHINJI NISHIZAWA

2020 ◽  
Vol 7 (2) ◽  
pp. 403-408
Author(s):  
Muyassaroh Muyassaroh ◽  
Heru Muryawan ◽  
Nastiti Dwi Cahyani

Latar belakang: Penyakit ginjal kronis (PGK) adalah kerusakan ginjal atau penurunan laju filtrasi glomerulus (GFR) kurang dari 60 mL / min / 1,73 m2 paling sedikit 3 bulan. Pasien PGK memiliki resiko kejadian kurang pendengaran yang tinggi. Tujuan: Mengetahui gambaran audiogram anak dengan PGK yang menjalani hemodialisis. Metode : Diskriptif retrospektif  7 kasus PGK ada anak yang menjalani hemodialisis di RSUP Dr.Kariadi Semarang Juli 2017. Hasil : didapatkan 5 kasus(71,4%) kurang pendengaran sensorineural, 1 kasus (14,3%) kurang pendengaran campuran (MHL) dan 1 kasus (14,3%) normal. Derajat kurang pendengaran bervariasi dari derajat ringan sampai sangat berat. Kesimpulan: Kurang pendengaran sensorineural sebagian besar terjadi pada anak dengan PGK yang menjalani hemodialisis. Kata kunci : Audiogram, SNHL, PGK   Background: Chronic kidney disease (CKD) is kidney damage or a decrease in glomerular filtration rate (GFR) of less than 60 mL / min / 1.73 m2 for at least 3 months. Patients with CKD have a high risk of hearing loss. Objective: The aim of illustrate the audiogram on  children with chronic kidney disease undergoing hemodialysis. Methode : Descriptif retrospective to seven cases of children with chronic kidney disease who undergoing hemodialysis in Karyadi hospital juli 2017. Result : Five cases (71,4%) with sensorineural hearing loss. One case(14,3%) showed severe mix hearing loss, one cases(14,3%)  with normal audiogram. The degree of hearing loss  from mild to profound Conclusion: Sensorineural hearing loss may occur in the majority of children with CKD on hemodialysis   Keywords : Audiogram, SNHL, PGK


PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 808-808
Author(s):  
KAREN D. HENDRICKS-MUNOZ ◽  
JOSEPH P. WALTON

We concur with Nield et al who point out that progressive sensorineural hearing loss is not limited to infants with persistent fetal circulation. It was not the intent of the study to imply that delayed hearing loss was limited to infants with persistent fetal circulation. Our center routinely refers for serial audiologic testing all infants who meet the high-risk registry criteria for deafness (ASHA 1984;26:17-21). Unfortunately, many of the infants in the study did not meet criteria established by the registry and, therefore, were not referred for evaluation.


2018 ◽  
Vol 65 (4) ◽  
pp. 328-335 ◽  
Author(s):  
Marcela Fandiño-Cárdenas ◽  
Alvaro J Idrovo ◽  
Roman Velandia ◽  
Jessica Molina-Franky ◽  
Jorge L Alvarado-Socarras

Abstract Objective The objectives of this study were to describe the findings of the auditory screening in children of mothers with ZIKV during pregnancy or suspicious of congenital ZIKV, and to determine whether hearing loss was in the first 2 years in life, regardless of whether microcephaly was also present. Methods This is a cases report. The information was collected and recorded in a database between January 2016 and April 2018. We perform two auditory tests to 3 and 24 months of life. The study was developed in Aguachica (Cesar, Colombia). It is considered a high-risk area for ZIKV infection. Participants included children of mothers with confirmed ZIKV during pregnancy or suspicious of congenital ZIKV exposure of ZIKV infection during an epidemic period in a tropical area. We defined a positive case according to the epidemiological definition and clinical criteria based on maternal symptoms. However, other children of mothers without clinical signs of Zika were evaluated at the same time. The main outcome was the presence of sensorineural hearing loss. Results The median age in the study group (n = 43) was 3.5 months (rank: 0–6) and the comparison group (n: 23, children of mothers without clinical signs of ZIKV) was 3 months (rank: 0–12). Screening hearing test was done using distortion product otoacustic emissions. At 3 months follow-up, children were evaluated using distortion product otoacustic emissions and automatized auditory brainstem response. None of the patients evaluated in this study were found to have sensorineural hearing loss. Conclusions We did not find hearing loss during the first 2 years in the children whose mother showed Zika during pregnancy. We recommend these children must be assessed to closed because there is a high risk the hearing loss as it usually may occur with CMV.


2020 ◽  
Vol 8 (10) ◽  
pp. 1516
Author(s):  
Giulia Chiopris ◽  
Piero Veronese ◽  
Francesca Cusenza ◽  
Michela Procaccianti ◽  
Serafina Perrone ◽  
...  

Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection and is the leading non-genetic cause of sensorineural hearing loss (SNLH) and an important cause of neurodevelopmental disabilities. The risk of intrauterine transmission is highest when primary infection occurs during pregnancy, with a higher rate of vertical transmission in mothers with older gestational age at infection, while the risk of adverse fetal effects significantly increases if fetal infection occurs during the first half of pregnancy. Despite its prevalence and morbidity among the neonatal population, there is not yet a standardized diagnostic test and therapeutic approach for cCMV infection. This narrative review aims to explore the latest developments in the diagnosis and treatment of cCMV infection. Literature analysis shows that preventive interventions other than behavioral measures during pregnancy are still lacking, although many clinical trials are currently ongoing to formulate a vaccination for women before pregnancy. Currently, we recommend using a PCR assay in blood, urine, and saliva in neonates with suspected cCMV infection. At present, there is no evidence of the benefit of antiviral therapy in asymptomatic infants. In the case of symptomatic cCMV, we actually recommend treatment with oral valganciclovir for a duration of 12 months. The effectiveness and tolerability of this therapy option have proven effective for hearing and neurodevelopmental long-term outcomes. Valganciclovir is reserved for congenitally-infected neonates with the symptomatic disease at birth, such as microcephaly, intracranial calcifications, abnormal cerebrospinal fluid index, chorioretinitis, or sensorineural hearing loss. Treatment with antiviral drugs is not routinely recommended for neonates with the mildly symptomatic disease at birth, for neonates under 32 weeks of gestational age, or for infants more than 30 days old because of insufficient evidence from studies. However, since these populations represent the vast majority of neonates and infants with cCMV infection and they are at risk of developing late-onset sequelae, a biomarker able to predict long-term sequelae should also be found to justify starting treatment and reducing the burden of CMV-related complications.


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