Are the changes in diagnostic criteria for gestational diabetes mellitus reflected in perinatal outcomes? A retrospective assessment

2019 ◽  
Vol 59 (5) ◽  
pp. 693-698 ◽  
Author(s):  
David M. T. Ehmann ◽  
Peter E. Hickman ◽  
Julia M. Potter
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Katja Erjavec ◽  
Tamara Poljičanin ◽  
Ratko Matijević

Objectives. To determine the impact of the implementation of new WHO diagnostic criteria for gestational diabetes mellitus (GDM) on prevalence, predictors, and perinatal outcomes in Croatian population.Methods. A cross-sectional study was performed using data from medical birth certificates collected in 2010 and 2014. Data collected include age, height, and weight before and at the end of pregnancy, while perinatal outcome was assessed by onset of labor, mode of delivery, and Apgar score.Results. A total of 81.748 deliveries and 83.198 newborns were analysed. Prevalence of GDM increased from 2.2% in 2010 to 4.7% in 2014. GDM was a significant predictor of low Apgar score (OR 1.656), labor induction (OR 2.068), and caesarean section (OR 1.567) in 2010, while in 2014 GD was predictive for labor induction (OR 1.715) and caesarean section (OR 1.458) only. Age was predictive for labor induction only in 2014 and for caesarean section in both years, while BMI before pregnancy was predictive for all observed perinatal outcomes in both years.Conclusions. Despite implementation of new guidelines, GDM remains burdened with increased risk of labor induction and caesarean section, but no longer with low Apgar score, while BMI remains an important predictor for all three perinatal outcomes.


2018 ◽  
Vol 19 (11) ◽  
pp. 3696 ◽  
Author(s):  
Anna Pleskacova ◽  
Vendula Bartakova ◽  
Katarina Chalasova ◽  
Lukas Pacal ◽  
Katerina Kankova ◽  
...  

Uric acid (UA) levels are associated with many diseases including those related to lifestyle. The aim of this study was to evaluate the influence of clinical and anthropometric parameters on UA and xanthine (X) levels during pregnancy and postpartum in women with physiological pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM), and to evaluate their impact on adverse perinatal outcomes. A total of 143 participants were included. Analyte levels were determined by HPLC with ultraviolet detection (HPLC-UV). Several single-nucleotide polymorphisms (SNPs) in UA transporters were genotyped using commercial assays. UA levels were higher within GDM women with pre-gestational obesity, those in high-risk groups, and those who required insulin during pregnancy. X levels were higher in the GDM group during pregnancy and also postpartum. Positive correlations between UA and X levels with body mass index (BMI) and glycemia levels were found. Gestational age at delivery was negatively correlated with UA and X levels postpartum. Postpartum X levels were significantly higher in women who underwent caesarean sections. Our data support a possible link between increased UA levels and a high-risk GDM subtype. UA levels were higher among women whose glucose tolerance was severely disturbed. Mid-gestational UA and X levels were not linked to adverse perinatal outcomes.


Diabetologia ◽  
2018 ◽  
Vol 61 (8) ◽  
pp. 1889-1891
Author(s):  
Sarah H. Koning ◽  
Jelmer J. van Zanden ◽  
Klaas Hoogenberg ◽  
Helen L. Lutgers ◽  
Alberdina W. Klomp ◽  
...  

2011 ◽  
Vol 194 (7) ◽  
pp. 338-340 ◽  
Author(s):  
Robert G Moses ◽  
Gary J Morris ◽  
Peter Petocz ◽  
Fernando San Gil ◽  
Dinesh Garg

2019 ◽  
Vol 43 (8) ◽  
pp. 606-612
Author(s):  
Wilson Kwong ◽  
Joel G. Ray ◽  
Wei Wu ◽  
Denice S. Feig ◽  
Julia Lowe ◽  
...  

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