scholarly journals Re Facial aesthetic injections in clinical practice: Pretreatment and post‐treatment consensus recommendations to minimise adverse outcome Region‐specific changes in line with the Covid‐19 pandemic

2020 ◽  
Vol 61 (4) ◽  
pp. 362-366
Author(s):  
Greg J Goodman ◽  
Steven Liew ◽  
Peter Callan ◽  
Sarah Hart ◽  
Naveen Somia ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Adverse Outcome ◽  
Post Treatment ◽  
Consensus Recommendations ◽  
Treatment Consensus

scholarly journals Magnetic resonance enterography features of small bowel Crohn’s disease activity: an inter-rater reliability study of small bowel active inflammation in clinical practice setting

2019 ◽  
Vol 92 (1099) ◽  
pp. 20180930
Author(s):  
Richard Tsai ◽  
Aaron Mintz ◽  
Michael Lin ◽  
Joyce Mhlanga ◽  
Adeeti Chiplunker ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Clinical Practice ◽  
Magnetic Resonance ◽  
Small Bowel ◽  
Magnetic Resonance Enterography ◽  
Post Treatment ◽  
Interrater Agreement ◽  
Substantial Agreement ◽  
Mucosal Ulceration ◽  
Interclass Correlation

Objective: The aim of this study is to determine the interrater agreement in a clinical practice environment for the most commonly used magnetic resonance enterography (MRE) features of Crohn’s disease (CD). Methods: CD patients with MRE’s before and after treatment were retrospectively identified using search queries over a 7-year period (May 2017–September 2017). MRE features of CD comprising components of multiple CD scoring indices were scored by radiologists in the same segment of bowel. Agreement for nominal categorical and continuous variables was assessed using a κ and interclass correlation coefficients, respectively. Results: 80 scans comprised the study population. Moderate interrater agreement was seen in both the pre- and post-treatment MRE’s for presence of diffusion restriction (к = 0.43, 0.48; pre- and post-treatment), stricturing disease (к = 0.51, 0.52), overall degree of severity (к = 0.49, 0.59). Substantial agreement was seen in pre- and post-treatment scans for length of involvement (interclass correlation coefficient = 0.67, 0.61). The presence of mucosal ulceration had no agreement (к = −0.07, –0.042). Conclusion: Many MRE features of active CD comprising the major CD scoring indices are reproducible when interpreted by non-CD focused abdominal radiologists. However, the presence of mucosal ulcerations had no agreement and may need more investigation before including this feature as a driver in therapeutic decision making. Advances in knowledge: Demonstrates the unreliability of mucosal ulceration by non-CD focused abdominal radiologists, targeting a potential area for future education. Key Points The majority of MRE findings incorporated in to many CD scoring indices have fair to moderate inter-rater agreement even when read by non-MRE expert radiologists. Substantial agreement was seen in the length of involved bowel, but this feature is only incorporated in to one of the CD scoring indices. Presence of mucosal ulcerations had no interrater agreement in our study—a feature which is heavily weighted by several CD scoring indices. Research should be focused bridging those features which have poor interrater agreement.

Role of Coronary Flow Velocity in Predicting Adverse Outcome in Clinical Practice

2018 ◽  
Vol 44 (7) ◽  
pp. 1402-1410 ◽  
Author(s):  
Angela Zagatina ◽  
Nadezhda Zhuravskaya ◽  
Maxim Kamenskikh ◽  
Dmitry Shmatov ◽  
Sergey Sayganov ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Flow Velocity ◽  
Coronary Flow ◽  
Adverse Outcome ◽  
Coronary Flow Velocity

Real-world use of epic for clinical practice (EPIC-CP) to assess patient-reported prostate cancer quality of life in the clinical setting.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 18-18 ◽  
Author(s):  
Peter Chang ◽  
Arie Carneiro ◽  
Ostap Dovirak ◽  
Kimberly Taylor ◽  
Catrina Crociani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Clinical Practice ◽  
Clinical Care ◽  
Post Treatment ◽  
Rank Test ◽  
Routine Clinical Care ◽  
Patient Reported ◽  
Domain Scores

18 Background: Prostate cancer practitioners tend to underestimate patients’ treatment-related side effects. We developed the Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP) to facilitate patient-reported health-related quality of life (HRQOL) assessment at the point-of-care (Chang P et al, J Urol Sep 2011). We sought to demonstrate the feasibility of EPIC-CP use in routine clinical care, and to compare longitudinal patient-reported and practitioner-reported prostate cancer outcomes. Methods: We reviewed practitioner- and patient-reported HRQOL outcomes in 482 patients who underwent radical prostatectomy at our institution from 2010 to 2014. All EPIC-CP questionnaires were administered and interpreted without research personnel. Practitioner-reported outcomes were assessed using chart review. We used the paired t-test and Wilcoxon signed-rank test to compare pre- and post-treatment EPIC-CP domain scores, and Fisher’s exact test to compare patient-reported and practitioner-reported outcomes. We considered p-values < 0.05 statistically significant. Results: 708 total EPIC-CP questionnaires were completed. Mean urinary incontinence domain scores increased (worsened) significantly from baseline (0.6±0.2) to 3 (3.1±2.3) and 6 months (2.2±2.1) post-treatment, but were not statistically changed from baseline at 12 months (1.6±1.7). Patient-reported incontinence pad-free rates using EPIC-CP at 3, 6, and 12 months were 47%, 76%, and 78%, respectively, which were consistent with practitioner-reported rates. Mean sexual domain scores were significantly worse at 12 months (5.9±3.3) compared to baseline (2.4±2.8). Practitioners significantly overestimated the rate of functional erections compared to patients’ EPIC-CP-reported rates at 3 months (18% vs 12%, p < 0.05) and 12 months (45% vs 23%, p < 0.05). Bowel and vitality/hormonal scores were unchanged, and urinary irritation/obstruction scores improved after surgery. Conclusions: EPIC-CP is feasible to use in the routine clinical care of prostate cancer patients, and can help practitioners more accurately assess patients’ post-treatment symptom severity.

Clinical Practice Patterns in Multiple Sclerosis Management: Mexican Consensus Recommendations

2021 ◽  
pp. 103053
Author(s):  
Eli Skromne-Eisenberg ◽  
Irene Treviño-Frenk ◽  
Gloria Lourdes Llamosa García-Velázquez ◽  
Sandra Quiñones-Aguilar ◽  
Verónica Rivas-Alonso ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Practice ◽  
Practice Patterns ◽  
Clinical Practice Patterns ◽  
Consensus Recommendations

Applicazioni cliniche degli studi RM perfusionali

1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 25-27 ◽  
Author(s):  
M. Gallucci
Keyword(s):  
Clinical Practice ◽  
Malignant Transformation ◽  
Post Treatment ◽  
Tumor Evolution ◽  
Main Application ◽  
Similar Reason ◽  
Differential Evaluation ◽  
Microvascular Proliferation ◽  
Ischaemic Necrosis

In clinical practice, perfusional MR has been successfully proposed in the study of pathophysiology of stroke, seeming able to help in distinguishing ischaemic necrosis from penumbra. In tumor evolution, the main application concerns the attempt of grading and follow up the lesions: areas in initial malignant transformation with microvascular proliferation in absence of endotelial (and BBB alterations), can be recognized. For the above, the tecnique is recommended in guiding cerebral biopsies toward correct triggers. For similar reason the differential evaluation of post-treatment necrosis from recurrency can take advantage from perfusional MR. Moreover, it could be predictable the possibility of employement in following tumors treated with genic therapy, in a simple and atraumatic way. In the field of epilepsy good correlations with PET and SPET has stayed on evaluating temporal perfusion in case of parahippocampal sclerosis. Promising perspectives are also present in metabolic-degenerative field. The correlation with PET studies in case of Alzheimer disesease, in fact, reaches 80%, with clear documentation of temporal and parietal cortical hypoperfusion. Our experience, performed with a 0.5 T operating magnet on more than 80 patients, confirms the results already reported in literature.

scholarly journals Use of fibrates in clinical practice: Queensland Lipid Group consensus recommendations

2012 ◽  
Vol 10 (3) ◽  
pp. 181-190 ◽  
Author(s):  
Ian Hamilton-Craig ◽  
Karam Maximilien Kostner ◽  
Stan Woodhouse ◽  
David Colquhoun
Keyword(s):  
Clinical Practice ◽  
Group Consensus ◽  
Consensus Recommendations
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