Drug‐related adverse effects of vismodegib and sonidegib for locally advanced or metastatic basal cell carcinoma

Matthew Gibson; Dedee Frances Murrell

doi:10.1111/ajd.13205

Drug‐related adverse effects of vismodegib and sonidegib for locally advanced or metastatic basal cell carcinoma

Australasian Journal of Dermatology ◽

10.1111/ajd.13205 ◽

2019 ◽

Vol 61 (2) ◽

pp. 176-177

Author(s):

Matthew Gibson ◽

Dedee Frances Murrell

Keyword(s):

Basal Cell Carcinoma ◽

Adverse Effects ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Metastatic Basal Cell Carcinoma

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Efficacy and tolerability of vismodegib treatment in locally advanced and metastatic basal cell carcinoma: retrospective real‐life data

Dermatologic Therapy ◽

10.1111/dth.15122 ◽

2021 ◽

Author(s):

Mustafa Gürbüz ◽

İzzet DoĞan ◽

Erman AkkuŞ ◽

Hande ErmiŞ ◽

Güngör Utkan ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Real Life ◽

Life Data ◽

Real Life Data ◽

Metastatic Basal Cell Carcinoma

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26200 Tumor burden in patients with locally advanced basal cell carcinoma and metastatic basal cell carcinoma following treatment with sonidegib: Results of the 42-month BOLT study

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2021.06.377 ◽

2021 ◽

Vol 85 (3) ◽

pp. AB89

Author(s):

Michael Migden ◽

Aaron S. Farberg ◽

James Spencer ◽

Felix Kiecker ◽

Alexander Guminski ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Tumor Burden ◽

Metastatic Basal Cell Carcinoma ◽

Advanced Basal Cell Carcinoma

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Long-term efficacy and safety of sonidegib in patients with locally advanced and metastatic basal cell carcinoma: 30-month analysis of the randomized phase 2 BOLT study

Journal of the European Academy of Dermatology and Venereology ◽

10.1111/jdv.14542 ◽

2017 ◽

Vol 32 (3) ◽

pp. 372-381 ◽

Cited By ~ 54

Author(s):

J.T. Lear ◽

M.R. Migden ◽

K.D. Lewis ◽

A.L.S. Chang ◽

A. Guminski ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Phase 2 ◽

Efficacy And Safety ◽

Term Efficacy ◽

Metastatic Basal Cell Carcinoma ◽

Randomized Phase 2

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Abstract LB-138: Efficacy data of GDC-0449, a systemic Hedgehog pathway antagonist, in a first-in-human, first-in-class Phase I study with locally advanced, multifocal or metastatic basal cell carcinoma patients

10.1158/1538-7445.am2008-lb-138 ◽

2008 ◽

Cited By ~ 5

Author(s):

Daniel D Von Hoff ◽

Charles M Rudin ◽

Patricia M LoRusso ◽

Mitesh J Borad ◽

Ronald L Korn ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Basal Cell ◽

Phase I Study ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Efficacy Data ◽

Metastatic Basal Cell Carcinoma

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A 12-month update of BOLT, a phase 2, randomized, double-blind study of sonidegib (LDE225) in patients with locally advanced or metastatic basal cell carcinoma

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2015.02.729 ◽

2015 ◽

Vol 72 (5) ◽

pp. AB178

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Blind Study ◽

Double Blind Study ◽

Phase 2 ◽

Double Blind ◽

Metastatic Basal Cell Carcinoma

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Targeting the Hedgehog Pathway for Locally Advanced and Metastatic Basal Cell Carcinoma

Current Pharmaceutical Design ◽

10.2174/1381612822666161208100325 ◽

2017 ◽

Vol 23 (4) ◽

pp. 655-659 ◽

Cited By ~ 12

Author(s):

Bita Esmaeli ◽

Vivian Yin

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Metastatic Basal Cell Carcinoma

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Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial

The Lancet Oncology ◽

10.1016/s1470-2045(15)70100-2 ◽

2015 ◽

Vol 16 (6) ◽

pp. 716-728 ◽

Cited By ~ 175

Author(s):

Michael R Migden ◽

Alexander Guminski ◽

Ralf Gutzmer ◽

Luc Dirix ◽

Karl D Lewis ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Phase 2 ◽

Double Blind ◽

Phase 2 Trial ◽

Metastatic Basal Cell Carcinoma ◽

Different Doses

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The use of Hedgehog pathway inhibitors for locally advanced and metastatic basal cell carcinoma

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2018.05.1160 ◽

2018 ◽

Vol 79 (3) ◽

pp. AB294

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Hedgehog Pathway ◽

Metastatic Basal Cell Carcinoma

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Faculty Opinions recommendation of Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725503664.793539334 ◽

2017 ◽

Author(s):

David Leffell

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Phase 2 ◽

Double Blind ◽

Phase 2 Trial ◽

Metastatic Basal Cell Carcinoma ◽

Different Doses

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432P Efficacy and tolerability of vismodegib treatment in locally advanced and metastatic basal cell carcinoma

Annals of Oncology ◽

10.1016/j.annonc.2020.10.424 ◽

2020 ◽

Vol 31 ◽

pp. S1410-S1411

Author(s):

M. Gürbüz ◽

I. Dogan ◽

G. Utkan ◽

F. Taş

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Metastatic Basal Cell Carcinoma

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