Molecular characterization, alternative splicing and expression analysis ofACSF2and its correlation with egg-laying performance in geese

2016 ◽  
Vol 47 (4) ◽  
pp. 451-462 ◽  
Author(s):  
S. Yu ◽  
W. Wei ◽  
M. Xia ◽  
Z. Jiang ◽  
D. He ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Molecular Characterization ◽  
Expression Analysis ◽  
Egg Laying ◽  
Laying Performance

scholarly journals RNA Expression Profile and Alternative Splicing Signatures of Genistein-Treated Breeder Hens Revealed by Hepatic Transcriptomic Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-19
Author(s):  
Zengpeng Lv ◽  
Jingle Jiang ◽  
Chao Ning ◽  
Hongjian Dai ◽  
Song Jin ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Immune Function ◽  
Expression Profiles ◽  
Egg Laying ◽  
High Dose ◽  
Rna Expression ◽  
Broiler Breeder ◽  
Breeder Hens ◽  
Laying Performance ◽  
Hepatic Transcriptome

Little information has been available about the influence of dietary genistein (GEN) on hepatic transcriptome of laying broiler breeder (LBB) hens. The study is aimed at broadening the understanding of RNA expression profiles and alternative splicing (AS) signatures of GEN-treated breeder hens and thereby improving laying performance and immune function of hens during the late egg-laying period. 720 LBB hens were randomly allocated into three groups with supplemental dietary GEN doses (0, 40 mg/kg, and 400 mg/kg). Each treatment has 8 replicates of 30 birds. Dietary GEN enhanced the antioxidative capability of livers, along with the increased activities of glutathione peroxidase and catalase. Furthermore, it improved lipid metabolic status and apoptotic process in the liver of hens. 40 mg/kg dietary GEN had the better effects on improving immune function and laying performance. However, transcriptome data indicated that 400 mg/kg dietary GEN did negative regulation of hormone biosynthetic process. Also, it upregulated the expressions of EDA2R and CYR61 by the Cis regulation of neighbouring genes (lncRNA_XLOC_018890 and XLOC_024242), which might activate NF-κB and immune-related signaling pathway. Furthermore, dietary GEN induced AS events in the liver, which also enriched into immune and metabolic process. Therefore, the application of 40 mg/kg GEN in the diet of breeder hens during the late egg-laying period can improve lipid metabolism and immune function. We need to pay attention to the side-effects of high-dose GEN on the immune function.

Molecular characterization, alternative splicing and expression analysis of bovine DBC1

Gene ◽  
2013 ◽  
Vol 527 (2) ◽  
pp. 689-693 ◽  
Author(s):  
Mingxun Li ◽  
Xiaomei Sun ◽  
Liushuai Hua ◽  
Yongzhen Huang ◽  
Jing Wang ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Molecular Characterization ◽  
Expression Analysis

scholarly journals Correction to: Molecular characterization and expression analysis of hepc1 and hepc2 in three tilapia species collected from Lake Manzala

2020 ◽  
Vol 44 (1) ◽  
Author(s):  
Karima F. Mahrous ◽  
Heba A. M. Abd El - Kader ◽  
Dalia M. Mabrouk ◽  
Mohamad M. Aboelenin ◽  
Noha M. Osman ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Expression Analysis ◽  
Lake Manzala

Molecular characterization and expression analysis of anti-Müllerian hormone in common carp (Cyprinus carpio) adult testes

2021 ◽  
Vol 40 ◽  
pp. 119169
Author(s):  
Marcos A. Oliveira ◽  
Emanuel R.M. Martinez ◽  
Arno J. Butzge ◽  
Lucas B. Doretto ◽  
Juliana M.B. Ricci ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Common Carp ◽  
Expression Analysis ◽  
Cyprinus Carpio ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio

scholarly journals Transcriptional responses in jejunum of two layer chicken strains following variations in dietary calcium and phosphorus levels

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Henry Reyer ◽  
Michael Oster ◽  
Siriluck Ponsuksili ◽  
Nares Trakooljul ◽  
Adewunmi O. Omotoso ◽  
...  
Keyword(s):  
Vitamin D ◽  
High Performance ◽  
Absorption Capacity ◽  
Egg Laying ◽  
Endocrine Regulation ◽  
Transcriptional Responses ◽  
Endogenous Factors ◽  
Mineral Homeostasis ◽  
Laying Performance ◽  
Vitamin D Levels

Abstract Background Calcium (Ca) and phosphorus (P) are essential nutrients that are linked to a large array of biological processes. Disturbances in Ca and P homeostasis in chickens are associated with a decline in growth and egg laying performance and environmental burden due to excessive P excretion rates. Improved utilization of minerals in particular of P sources contributes to healthy growth while preserving the finite resource of mineral P and mitigating environmental pollution. In the current study, high performance Lohmann Selected Leghorn (LSL) and Lohmann Brown (LB) hens at peak laying performance were examined to approximate the consequences of variable dietary Ca and P supply. The experimental design comprised four dietary groups with standard or reduced levels of either Ca or P or both (n = 10 birds per treatment group and strain) in order to stimulate intrinsic mechanisms to maintain homeostasis. Jejunal transcriptome profiles and the systemic endocrine regulation of mineral homeostasis were assessed (n = 80). Results Endogenous mechanisms to maintain mineral homeostasis in response to variations in the supply of Ca and P were effective in both laying hen strains. However, the LSL and LB appeared to adopt different molecular pathways, as shown by circulating vitamin D levels and strain-specific transcriptome patterns. Responses in LSL indicated altered proliferation rates of intestinal cells as well as adaptive responses at the level of paracellular transport and immunocompetence. Endogenous mechanisms in LB appeared to involve a restructuring of the epithelium, which may allow adaptation of absorption capacity via improved micro-anatomical characteristics. Conclusions The results suggest that LSL and LB hens may exhibit different Ca, P, and vitamin D requirements, which have so far been neglected in the supply recommendations. There is a demand for trial data showing the mechanisms of endogenous factors of Ca and P homeostasis, such as vitamin D, at local and systemic levels in laying hens.

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