Heavy alcohol consumption increases the risk of active tuberculosis in Taiwanese adults: a nation-wide population-based cohort study

Addiction ◽  
2017 ◽  
Vol 112 (12) ◽  
pp. 2124-2131 ◽  
Author(s):  
Yung-Feng Yen ◽  
Hsiao-Yun Hu ◽  
Ya-Ling Lee ◽  
Po-Wen Ku ◽  
Pei-Hung Chuang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Alcohol Consumption ◽  
Population Based ◽  
Active Tuberculosis ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption ◽  
Wide Population

scholarly journals Proximity of off-premise alcohol outlets and heavy alcohol consumption: A cohort study

2013 ◽  
Vol 132 (1-2) ◽  
pp. 295-300 ◽  
Author(s):  
Jaana I. Halonen ◽  
Mika Kivimäki ◽  
Marianna Virtanen ◽  
Jaana Pentti ◽  
S.V. Subramanian ◽  
...  
Keyword(s):  
Cohort Study ◽  
Alcohol Consumption ◽  
Alcohol Outlets ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption

scholarly journals Combined impact of smoking and heavy alcohol use on cognitive decline in early old age: Whitehall II prospective cohort study

2013 ◽  
Vol 203 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Gareth Hagger-Johnson ◽  
Séverine Sabia ◽  
Eric John Brunner ◽  
Martin Shipley ◽  
Martin Bobak ◽  
...  
Keyword(s):  
Cohort Study ◽  
Alcohol Consumption ◽  
Cognitive Decline ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Reference Group ◽  
Heavy Alcohol ◽  
Age Related ◽  
Heavy Alcohol Consumption ◽  
Combined Impact

BackgroundIdentifying modifiable risk factors for cognitive decline may inform prevention of dementia.AimsTo examine the combined impact of cigarette smoking and heavy alcohol consumption on cognitive decline from midlife.MethodProspective cohort study (Whitehall II cohort) with three clinical examinations in 1997/99, 2002/04 and 2007/09. Participants were 6473 adults (72% men), mean age 55.76 years (s.d. = 6.02) in 1997/99. Four cognitive tests, assessed three times over 10 years, combined into a global z-score (mean 0, s.d. = 1).ResultsAge-related decline in the global cognitive score was faster in individuals who were smoking heavy drinkers than in non-smoking moderate alcohol drinkers (reference group). The interaction term (P = 0.04) suggested that the combined effects of smoking and alcohol consumption were greater than their individual effects. Adjusting for age, gender, education and chronic diseases, 10-year decline in global cognition was −0.42 z-scores (95% Cl −0.45 to −0.39) for the reference group. In individuals who were heavy alcohol drinkers who also smoked the decline was −0.57 z-scores (95% Cl −0.67 to −0.48); 36% faster than the reference group.ConclusionsIndividuals who were smokers who drank alcohol heavily had a 36% faster cognitive decline, equivalent to an age-effect of 2 extra years over 10-year follow-up, compared with individuals who were non-smoking moderate drinkers.

scholarly journals Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors

2016 ◽  
Vol 31 (5) ◽  
pp. 305-312 ◽  
Author(s):  
J D Sluyter ◽  
A D Hughes ◽  
S A McG Thom ◽  
A Lowe ◽  
C A Camargo Jr ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Augmentation Index ◽  
Large Population ◽  
Population Based ◽  
Lifestyle Factors ◽  
Pressure Amplitude ◽  
Cross Sectional ◽  
Heavy Alcohol ◽  
Pacific People ◽  
Heavy Alcohol Consumption

Abstract Little is known about how aortic waveform parameters vary with ethnicity and lifestyle factors. We investigated these issues in a large, population-based sample. We carried out a cross-sectional analysis of 4798 men and women, aged 50–84 years from Auckland, New Zealand. Participants were 3961 European, 321 Pacific, 266 Maori and 250 South Asian people. We assessed modifiable lifestyle factors via questionnaires, and measured body mass index (BMI) and brachial blood pressure (BP). Suprasystolic oscillometry was used to derive aortic pressure, from which several haemodynamic parameters were calculated. Heavy alcohol consumption and BMI were positively related to most waveform parameters. Current smokers had higher levels of aortic augmentation index than non-smokers (difference=3.7%, P<0.0001). Aortic waveform parameters, controlling for demographics, antihypertensives, diabetes and cardiovascular disease (CVD), were higher in non-Europeans than in Europeans. Further adjustment for brachial BP or lifestyle factors (particularly BMI) reduced many differences but several remained. Despite even further adjustment for mean arterial pressure, pulse rate, height and total:high-density lipoprotein cholesterol, compared with Europeans, South Asians had higher levels of all measured aortic waveform parameters (for example, for backward pressure amplitude: β=1.5 mm Hg; P<0.0001), whereas Pacific people had 9% higher loge (excess pressure integral) (P<0.0001). In conclusion, aortic waveform parameters varied with ethnicity in line with the greater prevalence of CVD among non-white populations. Generally, this was true even after accounting for brachial BP, suggesting that waveform parameters may have increased usefulness in capturing ethnic variations in cardiovascular risk. Heavy alcohol consumption, smoking and especially BMI may partially contribute to elevated levels of these parameters.

scholarly journals Coronary deaths during Midsummer festival in Finland: miseries of long, light nights

2021 ◽  
Author(s):  
Simo Näyhä
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Alcohol Consumption ◽  
Negative Binomial ◽  
Negative Binomial Regression ◽  
Adverse Consequence ◽  
Heavy Alcohol ◽  
Summer Peak ◽  
Binomial Regression ◽  
Heavy Alcohol Consumption

AbstractThis paper examines whether the anomalous summer peak in deaths from coronary heart disease (CHD) in Finland could be attributed to adverse effects of the Midsummer festival and alcohol consumption during the festival. Daily deaths from CHD and alcohol poisoning in Finland, 1961–2014, that occurred during the 7 days centering on Midsummer Day were analysed in relation to deaths during 14 to 4 days before and 4 to 14 after Midsummer Day. Daily counts of deaths from CHD among persons aged 35–64 years were regressed on days around the Midsummer period by negative binomial regression. Mortality from CHD was highest on Midsummer Day (RR 1.25 (95% confidence interval 1.12–1.31), one day after the peak in deaths from alcohol poisonings. RR for CHD on Midsummer Day was particulary high (RR = 1.43; 1.09–1.86) in the 2000s, 30% of deaths being attributable to that day. In conclusion, the anomalous and prominent summer peak in deaths from CHD in Finland is an adverse consequence of the Midsummer festival. The most likely underlying reason is heavy alcohol consumption during the festival period, especially on Midsummer Eve. In the 2000s, one third of deaths from CHD on Midsummer Day are preventable.

scholarly journals Current Heavy Alcohol Consumption is Associated with Greater Cognitive Impairment in Older Adults

2016 ◽  
Vol 40 (11) ◽  
pp. 2435-2444 ◽  
Author(s):  
Adam J. Woods ◽  
Eric C. Porges ◽  
Vaughn E. Bryant ◽  
Talia Seider ◽  
Assawin Gongvatana ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Alcohol Consumption ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption

Abstract P002: Heavy Alcohol Consumption Increases the Risk of Atrial Fibrillation -Circulatory Risk in Communities Study(CIRCS)

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Fumihiko Sano ◽  
Tetsuya Ohira ◽  
Akihiko Kitamura ◽  
Hironori Imano ◽  
Renzhe Cui ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Alcohol Consumption ◽  
Medical History ◽  
Moderate Alcohol Consumption ◽  
Heavy Alcohol ◽  
Ethanol Drinking ◽  
Wide Range ◽  
Detailed Medical History ◽  
Heavy Alcohol Consumption

Background— Evidence on the relationship of a wide range of alcohol consumption with risk of incident atrial fibrillation has been limited. Methods— Between 1991 and 1995, 8602 Japanese men and women aged 30 to 80 years and free of clinical atrial fibrillation took part in the first examination of the Circulatory Risk in Communities Study(CIRCS)- a population based cohort study of cardiovascular risk factors, cardiovascular disease incidence, and their trends in Japanese communities. In the first examination, we checked a detailed medical history, physical examination, blood and urine examination, and electrocardiogram (ECG). An interviewer obtained histories in detail for weekly alcohol intake. In the follow-up period, incident atrial fibrillations were ascertained by annual ECG record and medical history of treatment of atrial fibrillation. ECGs were coded with the Minnesota Code by trained physician-epidemiologists. Differences in baseline characteristics between atrial fibrillation cases and controls were compared using Student t-tests or chi-squared tests. The hazard ratios (HRs) of incidence of atrial fibrillation and 95% confidence interval (CI) relative to the never-drinking group were calculated with adjustment for age and other potential confounding factors using the Cox proportional hazard model. Results— During an average follow-up of 6.4 years, 290 incident atrial fibrillation occurred. The higher incidence rate of atrial fibrillation was observed among participants with more than 69 g of ethanol drinking per week, compared with less than 69 g of ethanol drinking per week. On the other hand, light to moderate alcohol consumption was not associated with risk of atrial fibrillation. Compared with the never drinking group, the multivariable-adjusted HRs of past, light (<23 g), light moderate (23-46 g), moderate (46-69 g), and heavy (>69 g) drinking groups were 1.20 (95% CI, 0.61-2.35), 0.85 (95% CI, 0.57-1.27), 1.05 (95% CI, 0.63-1.75), 1.34 (95% CI, 0.78-2.32), and 2.92 (95% CI, 1.61-5.28), respectively. Conclusions— Heavy alcohol consumption was associated with the higher risk of atrial fibrillation, whereas there was no association of less than moderate alcohol consumption and atrial fibrillation.

scholarly journals Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0134044 ◽  
Author(s):  
Xin-Pei Wang ◽  
Fan Lei ◽  
Feng Du ◽  
Yu-Shuang Chai ◽  
Jing-Fei Jiang ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Gastrointestinal Mucosa ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption
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