Frontostriatal circuits, resting state functional connectivity and cognitive control in internet gaming disorder

2016 ◽  
Vol 22 (3) ◽  
pp. 813-822 ◽  
Author(s):  
Kai Yuan ◽  
Dahua Yu ◽  
Chenxi Cai ◽  
Dan Feng ◽  
Yangding Li ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Cognitive Control ◽  
Resting State ◽  
Internet Gaming Disorder ◽  
Gaming Disorder ◽  
Resting State Functional Connectivity ◽  
Internet Gaming

scholarly journals Altered resting-state functional connectivity of the insula in young adults with Internet gaming disorder

2015 ◽  
Vol 21 (3) ◽  
pp. 743-751 ◽  
Author(s):  
Jin-Tao Zhang ◽  
Yuan-Wei Yao ◽  
Chiang-Shan R. Li ◽  
Yu-Feng Zang ◽  
Zi-Jiao Shen ◽  
...  
Keyword(s):  
Young Adults ◽  
Functional Connectivity ◽  
Resting State ◽  
Internet Gaming Disorder ◽  
Gaming Disorder ◽  
Resting State Functional Connectivity ◽  
Internet Gaming

scholarly journals Differences in resting-state functional connectivity according to the level of impulsiveness in patients with internet gaming disorder

2021 ◽  
Vol 10 (1) ◽  
pp. 88-98
Author(s):  
Soo-Jeong Kim ◽  
Min-Kyeong Kim ◽  
Yu-Bin Shin ◽  
Hesun Erin Kim ◽  
Jun Hee Kwon ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Resting State ◽  
Inferior Frontal Gyrus ◽  
Internet Gaming Disorder ◽  
Healthy Controls ◽  
Gaming Disorder ◽  
Resting State Functional Connectivity ◽  
Brain Functions ◽  
Internet Gaming

AbstractBackground and aimsImpulsiveness is an important factor in the pathophysiology of Internet gaming disorder (IGD), and regional brain functions can be different depending on the level of impulsiveness. This study aimed to demonstrate that different brain mechanisms are involved depending on the level of impulsiveness among patients with IGD.MethodsResting-state functional MRI data were obtained from 23 IGD patients with high impulsivity, 27 IGD patients with low impulsivity, and 22 healthy controls, and seed-based functional connectivity was compared among the three groups. The seed regions were the ventromedial prefrontal cortex (vmPFC), dorsolateral prefrontal cortex, nucleus accumbens (NAcc), and amygdala.ResultsConnectivity of the vmPFC with the left temporo-parietal junction (TPJ) and NAcc-left insula connectivity were significantly decreased in the patients with high impulsivity, compared with the patients with low impulsivity and healthy controls. On the other hand, amygdala-based connectivity with the left inferior frontal gyrus showed decreases in both patient groups, compared with the healthy controls.ConclusionThese findings may suggest a potential relationship between impulsivity and deficits in reward-related social cognition processes in patients with IGD. In particular, certain interventions targeted at vmPFC-TPJ connectivity, found to be impulsivity-specific brain connectivity, are likely to help with addiction recovery among impulsive patients with IGD.

scholarly journals Altered Functional Connectivity of the Insula and Nucleus Accumbens in Internet Gaming Disorder: A Resting State fMRI Study

2016 ◽  
Vol 22 (4) ◽  
pp. 192-200 ◽  
Author(s):  
Chiao-Yun Chen ◽  
Ju-Yu Yen ◽  
Peng-Wei Wang ◽  
Gin-Chung Liu ◽  
Cheng-Fang Yen ◽  
...  
Keyword(s):  
Nucleus Accumbens ◽  
Functional Connectivity ◽  
Frontal Lobe ◽  
Resting State ◽  
Internet Gaming Disorder ◽  
Resting State Fmri ◽  
Gaming Disorder ◽  
Internet Gaming ◽  
Left Dlpfc ◽  
The Right

Aims: A possible addiction mechanism has been represented by altered functional connectivity (FC) in the resting state. The aim of this study was to evaluate the FCs of the insula and nucleus accumbens among subjects with Internet gaming disorder (IGD). Methods: We recruited 30 males with IGD and 30 controls and evaluated their FC using functional magnetic imaging scanning under resting, a state with relaxation, closed eyes, with inducement to think of nothing systematically, become motionless, and instructed not to fall asleep. Results: Subjects with IGD had a lower FC with the left insula over the left dorsolateral prefrontal cortex (DLPFC) and orbital frontal lobe and a higher FC with the insula with the contralateral insula than controls. The inter-hemispheric insula connectivity positively correlated with impulsivity. Further, they had lower FC with the left nucleus accumbens over the left DLPFC and with the right nucleus accumbens over the left DLPFC, and insula and a higher FC with that over the right precuneus. Conclusion: The elevated inter-hemispheric insula FC is found to be associated with impulsivity and might explain why it is involved in IGD. The attenuated frontostriatal suggests that the emotion-driven gaming urge through nucleus accumbens could not be well regulated by the frontal lobe of subjects with IGD.

scholarly journals Relationship between Resting-State Alpha Coherence and Cognitive Control in Individuals with Internet Gaming Disorder: A Multimodal Approach Based on Resting-State Electroencephalography and Event-Related Potentials

2021 ◽  
Vol 11 (12) ◽  
pp. 1635
Author(s):  
Minkyung Park ◽  
So Young Yoo ◽  
Ji-Yoon Lee ◽  
Ja Wook Koo ◽  
Ung Gu Kang ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Resting State ◽  
Internet Gaming Disorder ◽  
Event Related Potentials ◽  
Brain Regions ◽  
Event Related Potential ◽  
Gaming Disorder ◽  
Addictive Disorders ◽  
Internet Gaming ◽  
Related Potentials

The human brain is constantly active, even at rest. Alpha coherence is an electroencephalography (EEG) rhythm that regulates functional connectivity between different brain regions. However, the relationships between resting-state alpha coherence and N2/P3 components associated with response inhibition and cognitive processes have not been investigated in addictive disorders. The present study investigated the relationships between alpha coherence during the resting state and N2/P3 components of event-related potentials during the Go/Nogo task in healthy controls (HCs) and patients with Internet gaming disorder (IGD). A total of 64 young adults (HC: n = 31; IGD: n = 33) participated in this study. Alpha coherence values at left fronto-central and bilateral centro-temporal electrode sites were significantly correlated with P3 latency in HCs, whereas inverse correlations were observed in patients with IGD. Furthermore, significant differences were observed in the correlation values between the groups. Our results suggest that patients with IGD lack dynamic interactions of functional connectivity between the fronto-centro-temporal regions during the resting state and the event-related potential (ERP) index during cognitive tasks. The findings of this study may have important implications for understanding the neurophysiological mechanisms linking resting-state EEG and task-related ERPs underlying IGD.

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