scholarly journals Alterations in White Matter Microstructure and Connectivity in Young Adults with Alcohol Use Disorder

2019 ◽  
Author(s):  
Evgeny J. Chumin ◽  
Gregory G. Grecco ◽  
Mario Dzemidzic ◽  
Hu Cheng ◽  
Peter Finn ◽  
...  
Keyword(s):  
Young Adults ◽  
White Matter ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
White Matter Microstructure

scholarly journals Differences in White Matter Microstructure and Connectivity in Nontreatment-Seeking Individuals with Alcohol Use Disorder

2018 ◽  
Vol 42 (5) ◽  
pp. 889-896 ◽  
Author(s):  
Evgeny J. Chumin ◽  
Joaquín Goñi ◽  
Meredith E. Halcomb ◽  
Timothy C. Durazzo ◽  
Mario Dzemidzic ◽  
...  
Keyword(s):  
White Matter ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
White Matter Microstructure

scholarly journals Effects of Aging on Frontal White Matter Microstructure in Alcohol Use Disorder and Associations With Processing Speed

2015 ◽  
Vol 76 (2) ◽  
pp. 296-306 ◽  
Author(s):  
Scott F. Sorg ◽  
Lindsay M. Squeglia ◽  
Michael J. Taylor ◽  
Omar M. Alhassoon ◽  
Lisa M. Delano-Wood ◽  
...  
Keyword(s):  
White Matter ◽  
Alcohol Use ◽  
Processing Speed ◽  
Alcohol Use Disorder ◽  
White Matter Microstructure ◽  
Frontal White Matter ◽  
Effects Of Aging

Drinking Together and Drinking Alone: A Social-Contextual Framework for Examining Risk for Alcohol Use Disorder

2020 ◽  
pp. 096372142096940
Author(s):  
Kasey G. Creswell
Keyword(s):  
Young Adults ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Positive Emotions ◽  
Social Experiences ◽  
Adolescents And Young Adults ◽  
Clinical Implications ◽  
Social Drinking ◽  
Contextual Framework ◽  
Regulatory Functions

The context in which drinking occurs is a critical but relatively understudied factor in alcohol use disorder (AUD) etiology. In this article, I offer a social-contextual framework for examining AUD risk by reviewing studies on the unique antecedents and deleterious consequences of social compared with solitary alcohol use in adolescents and young adults. Specifically, I provide evidence of distinct emotion regulatory functions across settings, in which social drinking is linked to enhancing positive emotions and social experiences, and solitary drinking is linked to coping with negative emotions. I end by considering the conceptual, methodological, and clinical implications of this social-contextual account of AUD risk.

scholarly journals Microstructural damage of white-matter tracts connecting large-scale networks is related to impaired executive profile in alcohol use disorder

2020 ◽  
Vol 25 ◽  
pp. 102141 ◽  
Author(s):  
Chiara Crespi ◽  
Caterina Galandra ◽  
Nicola Canessa ◽  
Marina Manera ◽  
Paolo Poggi ◽  
...  
Keyword(s):  
White Matter ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Large Scale ◽  
White Matter Tracts ◽  
Microstructural Damage ◽  
Large Scale Networks

scholarly journals Corrigendum: White Matter Microstructure in Adolescents and Young Adults With Non-Suicidal Self-Injury

2020 ◽  
Vol 11 ◽  
Author(s):  
Melinda Westlund Schreiner ◽  
Bryon A. Mueller ◽  
Bonnie Klimes-Dougan ◽  
Erin D. Begnel ◽  
Mark Fiecas ◽  
...  
Keyword(s):  
Young Adults ◽  
White Matter ◽  
Adolescents And Young Adults ◽  
Self Injury ◽  
White Matter Microstructure

scholarly journals Nicotine Effects on White Matter Microstructure in Young Adults

2019 ◽  
Vol 35 (1) ◽  
pp. 10-21 ◽  
Author(s):  
Megan M Kangiser ◽  
Alicia M Thomas ◽  
Christine M Kaiver ◽  
Krista M Lisdahl
Keyword(s):  
Working Memory ◽  
Young Adults ◽  
White Matter ◽  
Fractional Anisotropy ◽  
Sustained Attention ◽  
Verbal Memory ◽  
Diffusion Tensor ◽  
Memory Performance ◽  
Mean Diffusivity ◽  
White Matter Microstructure

Abstract Objective Nicotine use is widely prevalent among youth, and is associated with white matter microstructural changes as measured by diffusion tensor imaging (DTI). In adults, nicotine use is generally associated with lower fractional anisotropy (FA), but in adolescents/young adults (≤30 years), microstructure appears healthier, indicated by higher FA. This cross-sectional study examined associations between nicotine use and white matter microstructure using fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) in young adults. Methods Fifty-three participants (18 nicotine users [10 female]/35 controls [17 female]) ages 18–25 underwent MRI scan, neuropsychological battery, toxicology screening, and drug use interview. Nicotine group associations with FA and MD were examined in various white matter tracts. In significant tracts, AD and RD were measured. Exploratory correlations were conducted between significant tracts and verbal memory and sustained attention/working memory performance. Results Nicotine users exhibited significantly lower FA than controls in the left anterior thalamic radiation, left inferior longitudinal fasciculus, left superior longitudinal fasciculus—temporal, and left uncinate fasciculus. In these tracts, AD and RD did not differ, nor did MD differ in any tract. White matter quality was positively correlated with sustained attention/working memory performance. Conclusions Cigarette smoking may disrupt white matter microstructure. These results are consistent with adult studies, but inconsistent with adolescent/young adult studies, likely due to methodological and sample age differences. Further studies should examine longitudinal effects of nicotine use on white matter microstructure in a larger sample.

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