scholarly journals Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure

2009 ◽  
Vol 13 (12) ◽  
pp. 3298-3313 ◽  
Author(s):  
Xiaoduan Ye ◽  
Patrick K. O'Neil ◽  
Adrienne N. Foster ◽  
Michal J. Gajda ◽  
Jan Kosinski ◽  
...  
Keyword(s):  
Protein Structure ◽  
High Throughput ◽  
Link Analysis ◽  
Experiment Planning ◽  
Cross Link

scholarly journals Advances in collagen cross-link analysis

Methods ◽  
2008 ◽  
Vol 45 (1) ◽  
pp. 65-74 ◽  
Author(s):  
David R. Eyre ◽  
Mary Ann Weis ◽  
Jiann-Jiu Wu
Keyword(s):  
Link Analysis ◽  
Cross Link

HIGH-THROUGHPUT KINETIC STUDY OF PEROXIDE CURING OF EPDM RUBBER

2011 ◽  
Vol 84 (1) ◽  
pp. 101-113 ◽  
Author(s):  
Johannes M. Kranenburg ◽  
Martin Van Duin ◽  
Ulrich S. Schubert
Keyword(s):  
Raman Spectroscopy ◽  
High Throughput ◽  
Hardness Measurement ◽  
Cross Link ◽  
High Throughput Experimentation ◽  
Peroxide Curing ◽  
Link Density ◽  
Cross Link Density ◽  
Solution Route ◽  
Set Up

Abstract Mixing of EPDM and a peroxide curative via a solution route and subsequent curing were performed in a downscaled set-up. The resulting vulcanizates were characterized by a down-scaled hardness measurement and by Raman spectroscopy in a high-throughput experimentation compatible approach. The characterization results obtained on these vulcanizates agreed well with those obtained on corresponding vulcanizates prepared via conventional mill mixing. By indentation on vulcanizates cured for various curing times, a rheometer curve could be constructed. The conversion of the EPDM unsaturation and, thus, the extent of the addition reactions was quantified by Raman spectroscopy. Using both the indentation and the Raman data, the cross-link density resulting from combination reactions was estimated.

scholarly journals Fast iodide-SAD phasing for high-throughput membrane protein structure determination

2017 ◽  
Vol 3 (5) ◽  
pp. e1602952 ◽  
Author(s):  
Igor Melnikov ◽  
Vitaly Polovinkin ◽  
Kirill Kovalev ◽  
Ivan Gushchin ◽  
Mikhail Shevtsov ◽  
...  
Keyword(s):  
Protein Structure ◽  
Membrane Protein ◽  
High Throughput ◽  
Structure Determination ◽  
Protein Structure Determination ◽  
Membrane Protein Structure ◽  
Sad Phasing ◽  
Membrane Protein Structure Determination

scholarly journals Meeting Review: Bioinformatics and Medicine – From Molecules to Humans, Virtual and Real

2002 ◽  
Vol 3 (3) ◽  
pp. 270-276
Author(s):  
Roslin Russell
Keyword(s):  
Protein Structure ◽  
Modeling And Simulation ◽  
High Throughput ◽  
Protein Interactions ◽  
Life Sciences ◽  
Systems Modeling ◽  
Protein Protein Interactions ◽  
Research Institutes ◽  
The Government ◽  
Structure Research

The Industrialization Workshop Series aims to promote and discuss integration, automation, simulation, quality, availability and standards in the high-throughput life sciences. The main issues addressed being the transformation of bioinformatics and bioinformaticsbased drug design into a robust discipline in industry, the government, research institutes and academia. The latest workshop emphasized the influence of the post-genomic era on medicine and healthcare with reference to advanced biological systems modeling and simulation, protein structure research, protein-protein interactions, metabolism and physiology. Speakers included Michael Ashburner, Kenneth Buetow, Francois Cambien, Cyrus Chothia, Jean Garnier, Francois Iris, Matthias Mann, Maya Natarajan, Peter Murray-Rust, Richard Mushlin, Barry Robson, David Rubin, Kosta Steliou, John Todd, Janet Thornton, Pim van der Eijk, Michael Vieth and Richard Ward.

High-throughput protein structure determination using grid computing

2009 ◽  
Author(s):  
Jason W. Schmidberger ◽  
Blair Bethwaite ◽  
Colin Enticott ◽  
Mark A. Bate ◽  
Steve G. Androulakis ◽  
...  
Keyword(s):  
Protein Structure ◽  
Grid Computing ◽  
High Throughput ◽  
Structure Determination ◽  
Protein Structure Determination
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