scholarly journals Inertial particle focusing in parallel microfluidic channels for high-throughput filtration

2011 ◽  
Author(s):  
J. Hansson ◽  
J.M. Karlsson ◽  
T. Haraldsson ◽  
W. van der Wijngaart ◽  
A. Russom
Keyword(s):  
High Throughput ◽  
Microfluidic Channels ◽  
Inertial Particle ◽  
Particle Focusing

Fundamentals of elasto-inertial particle focusing in curved microfluidic channels

Lab on a Chip ◽  
2016 ◽  
Vol 16 (14) ◽  
pp. 2626-2635 ◽  
Author(s):  
Nan Xiang ◽  
Xinjie Zhang ◽  
Qing Dai ◽  
Jie Cheng ◽  
Ke Chen ◽  
...  
Keyword(s):  
Flow Rate ◽  
Process Model ◽  
Microfluidic Channels ◽  
Inertial Particle ◽  
Particle Focusing ◽  
Stage Process

We experimentally explore the elasto-inertial particle focusing in curved microfluidic channels and propose a six-stage process model illustrating the particle focusing with increasing flow rate.

The Effect of Asymmetry on Particle Focusing in Microchannels

2011 ◽  
Vol 403-408 ◽  
pp. 482-485 ◽  
Author(s):  
Levent Trabzon ◽  
Huseyin Kizil ◽  
Levent Yobas ◽  
Arzu Ozbey ◽  
Mustafa Yilmaz ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
High Throughput ◽  
Channel Wall ◽  
The Other ◽  
Clear Relationship ◽  
Single Line ◽  
Microfluidic Channels ◽  
Throughput Performance ◽  
Particle Focusing ◽  
Curved Channels

We studied the effect of geometry on single focusing of particles in the passive microfluidic channels. There is a quantitative analysis of focusing on non-axisymmetric straight channels with two different unique designs as well as curved channels having symmetrical and asymmetrical radius of curvatures in one turn. We found that there is a clear relationship in existence of single line focusing with the degree of non-symmetry in microchannels. One-degree of asymmetry in straight channels does not induce any formation of single focusing, but single line focusing is pronounced by two-degree of asymmetry in straight channels. On the other hand, single line focusing in the curved channels is enhanced with asymmetrical radius of curvatures in one turn. The single line focusing in curved channels is seen at Rep values higher than 1, which gives us better continuous and high-throughput performance. The position of single focused particles in the microchannels is found to be 50 m with respect to the channel wall in the asymmetrical curved microchannels.

Multi-train elasto-inertial particle focusing in straight microfluidic channels

2016 ◽  
Vol 109 (13) ◽  
pp. 134101 ◽  
Author(s):  
Nan Xiang ◽  
Qing Dai ◽  
Zhonghua Ni
Keyword(s):  
Microfluidic Channels ◽  
Inertial Particle ◽  
Particle Focusing

Inertial particle focusing and spacing control in microfluidic devices

2018 ◽  
Vol 22 (3) ◽  
Author(s):  
Chao Wang ◽  
Sifan Sun ◽  
Ying Chen ◽  
Zhengdong Cheng ◽  
Yuxiu Li ◽  
...  
Keyword(s):  
Microfluidic Devices ◽  
Inertial Particle ◽  
Particle Focusing

scholarly journals Sheathless Dean-flow-coupled elasto-inertial particle focusing and separation in viscoelastic fluid

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3461-3469 ◽  
Author(s):  
Dan Yuan ◽  
Say Hwa Tan ◽  
Qianbin Zhao ◽  
Sheng Yan ◽  
Ronald Sluyter ◽  
...  
Keyword(s):  
Viscoelastic Fluid ◽  
Straight Channel ◽  
Inertial Particle ◽  
Channel Section ◽  
Dean Flow ◽  
Particle Focusing

Sheathless particle focusing and separation in viscoelastic fluid is demonstrated using an integrated ECCA (straight channel section with asymmetrical expansion–contraction cavity arrays) straight channel.

Dynamically tunable elasto-inertial particle focusing and sorting in microfluidics

Lab on a Chip ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 568-581 ◽  
Author(s):  
Yinning Zhou ◽  
Zhichao Ma ◽  
Ye Ai
Keyword(s):  
Microfluidic Device ◽  
Viscoelastic Fluids ◽  
Inertial Particle ◽  
Particle Focusing

We explore the use of non-Newtonian viscoelastic fluids to achieve size-tunable elasto-inertial particle focusing and sorting in a microfluidic device, and realize the controllable tunability among three separation thresholds.

scholarly journals High-Throughput Particle Concentration Using Complex Cross-Section Microchannels

Micromachines ◽  
2020 ◽  
Vol 11 (4) ◽  
pp. 440 ◽  
Author(s):  
Asma Mihandoust ◽  
Sajad Razavi Bazaz ◽  
Nahid Maleki-Jirsaraei ◽  
Majid Alizadeh ◽  
Robert A. Taylor ◽  
...  
Keyword(s):  
Cross Section ◽  
High Throughput ◽  
Cross Sections ◽  
Particle Concentration ◽  
Separation Efficiency ◽  
Channel Cross Section ◽  
Total Width ◽  
Particle Focusing ◽  
Complex Cross ◽  
Complex Cross Section

High throughput particle/cell concentration is crucial for a wide variety of biomedical, clinical, and environmental applications. In this work, we have proposed a passive spiral microfluidic concentrator with a complex cross-sectional shape, i.e., a combination of rectangle and trapezoid, for high separation efficiency and a confinement ratio less than 0.07. Particle focusing in our microfluidic system was observed in a single, tight focusing line, in which higher particle concentration is possible, as compared with simple rectangular or trapezoidal cross-sections with similar flow area. The sharper focusing stems from the confinement of Dean vortices in the trapezoidal region of the complex cross-section. To quantify this effect, we introduce a new parameter, complex focusing number or CFN, which is indicative of the enhancement of inertial focusing of particles in these channels. Three spiral microchannels with various widths of 400 µm, 500 µm, and 600 µm, with the corresponding CFNs of 4.3, 4.5, and 6, respectively, were used. The device with the total width of 600 µm was shown to have a separation efficiency of ~98%, and by recirculating, the output concentration of the sample was 500 times higher than the initial input. Finally, the investigation of results showed that the magnitude of CFN relies entirely on the microchannel geometry, and it is independent of the overall width of the channel cross-section. We envision that this concept of particle focusing through complex cross-sections will prove useful in paving the way towards more efficient inertial microfluidic devices.

Sign in / Sign up

Export Citation Format

Share Document