scholarly journals Sheathless Dean-flow-coupled elasto-inertial particle focusing and separation in viscoelastic fluid

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3461-3469 ◽  
Author(s):  
Dan Yuan ◽  
Say Hwa Tan ◽  
Qianbin Zhao ◽  
Sheng Yan ◽  
Ronald Sluyter ◽  
...  
Keyword(s):  
Viscoelastic Fluid ◽  
Straight Channel ◽  
Inertial Particle ◽  
Channel Section ◽  
Dean Flow ◽  
Particle Focusing

Sheathless particle focusing and separation in viscoelastic fluid is demonstrated using an integrated ECCA (straight channel section with asymmetrical expansion–contraction cavity arrays) straight channel.

Continuous plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion–contraction cavity arrays

Lab on a Chip ◽  
2016 ◽  
Vol 16 (20) ◽  
pp. 3919-3928 ◽  
Author(s):  
Dan Yuan ◽  
Jun Zhang ◽  
Ronald Sluyter ◽  
Qianbin Zhao ◽  
Sheng Yan ◽  
...  
Keyword(s):  
Viscoelastic Fluid ◽  
High Purity ◽  
Inertial Effects ◽  
Straight Channel ◽  
Dean Flow ◽  
Plasma Extraction

By exploiting the Dean-flow-coupled elasto-inertial effects, continuous, sheathless, and high purity plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion–contraction cavity arrays (ECCA channel) is demonstrated.

Microfluidic device for sheathless particle focusing and separation using a viscoelastic fluid

2015 ◽  
Vol 1406 ◽  
pp. 244-250 ◽  
Author(s):  
Jeonghun Nam ◽  
Bumseok Namgung ◽  
Chwee Teck Lim ◽  
Jung-Eun Bae ◽  
Hwa Liang Leo ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Viscoelastic Fluid ◽  
Particle Focusing

Inertial particle focusing and spacing control in microfluidic devices

2018 ◽  
Vol 22 (3) ◽  
Author(s):  
Chao Wang ◽  
Sifan Sun ◽  
Ying Chen ◽  
Zhengdong Cheng ◽  
Yuxiu Li ◽  
...  
Keyword(s):  
Microfluidic Devices ◽  
Inertial Particle ◽  
Particle Focusing

Dynamically tunable elasto-inertial particle focusing and sorting in microfluidics

Lab on a Chip ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 568-581 ◽  
Author(s):  
Yinning Zhou ◽  
Zhichao Ma ◽  
Ye Ai
Keyword(s):  
Microfluidic Device ◽  
Viscoelastic Fluids ◽  
Inertial Particle ◽  
Particle Focusing

We explore the use of non-Newtonian viscoelastic fluids to achieve size-tunable elasto-inertial particle focusing and sorting in a microfluidic device, and realize the controllable tunability among three separation thresholds.

Elasto-inertial particle focusing in 3D-printed microchannels with unconventional cross sections

2019 ◽  
Vol 23 (3) ◽  
Author(s):  
Wenlai Tang ◽  
Ning Fan ◽  
Jiquan Yang ◽  
Zongan Li ◽  
Liya Zhu ◽  
...  
Keyword(s):  
Cross Sections ◽  
Inertial Particle ◽  
Particle Focusing ◽  
3D Printed

Fundamentals of elasto-inertial particle focusing in curved microfluidic channels

Lab on a Chip ◽  
2016 ◽  
Vol 16 (14) ◽  
pp. 2626-2635 ◽  
Author(s):  
Nan Xiang ◽  
Xinjie Zhang ◽  
Qing Dai ◽  
Jie Cheng ◽  
Ke Chen ◽  
...  
Keyword(s):  
Flow Rate ◽  
Process Model ◽  
Microfluidic Channels ◽  
Inertial Particle ◽  
Particle Focusing ◽  
Stage Process

We experimentally explore the elasto-inertial particle focusing in curved microfluidic channels and propose a six-stage process model illustrating the particle focusing with increasing flow rate.

High-throughput particle focusing and separation in split-recombination channel

2022 ◽  
Vol 32 (2) ◽  
pp. 025007
Author(s):  
Shuang Chen ◽  
Zongqian Shi ◽  
Jiajia Sun ◽  
Shenli Jia ◽  
Mingjie Zhong ◽  
...  
Keyword(s):  
High Throughput ◽  
Lift Force ◽  
Curvature Radius ◽  
Straight Channel ◽  
Geometrical Structures ◽  
Inertial Focusing ◽  
Particle Focusing ◽  
Drag Forces ◽  
Recombination Channel ◽  
Flow Drag

Abstract Inertial microfluidic has been widely applied to manipulate particles or bio-sample based on the inertial lift force and Dean Vortices. This technology provides significant advantages over conventional technologies, including simple structure, high throughput and freedom from an external field. Among many inertial microfluidic systems, the straight microchannel is commonly used to produce inertial focusing, which is a phenomenon that particles or cells are aligned and separated based on their size under the influence of inertial lift force. Besides the inertial lift force, flow drag forces induced by the geometrical structures of microchannel can also affect particle focusing. Herein, a split-recombination microchannel, consisting of curved and straight channels, is proposed to focus and separate particles at high flow rate. As compared with the straight channel, the particle focusing in the split-recombination channel is greatly improved, which results from the combined effects of the inertial lift force, the curvature-induced Dean drag force and the structure of split and recombination. Moreover, the distribution of different-sized particles in designed microchannel is investigated. The results indicate that the proposed microchannel not only enhances the particle focusing but also enables the separation of different-sized particles with high throughput. Finally, it is discovered that the larger length of straight channel and curvature radius of curved channel can result in a more efficient particle separation. Another important feature of designed split-recombination microchannel is that it can be arranged in parallel to handle large-volume samples, holding great potential in lab-on-a-chip applications.

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