Evaluation of new complexes of biocompatible magnetic fluid and third generation of photosensitizer useful to cancer treatment

2005 ◽  
Vol 41 (10) ◽  
pp. 4105-4107 ◽  
Author(s):  
P.P. Macaroff ◽  
D.M. Oliveira ◽  
K.F. Ribeiro ◽  
Z.G.M. Lacava ◽  
E.C.D. Lima ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Magnetic Fluid ◽  
Third Generation

Study on Cancer Treatment using Magnetic Fluid for Medicine and Induction Heating Device

2013 ◽  
Vol 133 (6) ◽  
pp. 366-371 ◽  
Author(s):  
Hideo Nagae ◽  
Sotoshi Yamada ◽  
Yoshio Ikehata ◽  
Satoshi Yagitani ◽  
Isamu Nagano
Keyword(s):  
Cancer Treatment ◽  
Induction Heating ◽  
Magnetic Fluid ◽  
Heating Device

Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch

2020 ◽  
Vol 20 (17) ◽  
pp. 1994-2004 ◽  
Author(s):  
Pooja Ratre ◽  
Keerti Mishra ◽  
Amit Dubey ◽  
Amber Vyas ◽  
Akhlesh Jain ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Treatment ◽  
Postmenopausal Women ◽  
Aromatase Inhibitors ◽  
3D Structure ◽  
Postmenopausal Breast Cancer ◽  
Breast Cancer Treatment ◽  
Third Generation ◽  
Breast Cancer Chemotherapy

Background: Estrogens are essential for the growth of breast cancer in the case of premenopausal as well as in postmenopausal women. However, most of the breast cancer incidences are reported in postmenopausal women and the concurrent risk surges with an increase in age. Since the enzyme aromatase catalyses essential steps in estrogen biosynthesis, Aromatase Inhibitors (AIs) are effective targeted therapy in patients with Estrogen Receptor positive (ER+) breast cancer. AIs are more effective than Selective Estrogen Receptor Modulators (SERMs) because they block both the genomic and nongenomic activities of ER. Till date, first, second and third-generation AIs have been approved by the FDA. The third-generation AIs, viz. Letrozole, Anastrozole, Exemestane, are currently used in the standard treatment for postmenopausal breast cancer. Methods: Data were collected from Medline, PubMed, Google Scholar, Science Direct through searching of keywords: ‘aromatase’, ‘aromatase inhibitors’, ‘breast cancer’, ‘steroidal aromatase inhibitors’, ‘non-steroidal inhibitors’ and ‘generations of aromatase inhibitors’. Results: In the current scenario of breast cancer chemotherapy, AIs are the most widely used agents which reveal optimum efficacy along with the least side effects. Keeping in view the prominence of AIs in breast cancer therapy, this review covered the detailed description of aromatase including its role in the biosynthesis of estrogen, biochemistry, gene expression, 3D-structure, and information of reported AIs along with their role in breast cancer treatment. Conclusion: AIs are the mainstream solution of the ER+ breast cancer treatment regimen with the continuous improvement of human understanding of the importance of a healthy life of women suffering from breast cancer.

scholarly journals Induction Heating Analysis of Surface-Functionalized Nanoscale CoFe2O4 for Magnetic Fluid Hyperthermia toward Noninvasive Cancer Treatment

ACS Omega ◽  
2020 ◽  
Vol 5 (36) ◽  
pp. 23378-23384 ◽  
Author(s):  
Prashant B. Kharat ◽  
Sandeep B. Somvanshi ◽  
Pankaj P. Khirade ◽  
K. M. Jadhav
Keyword(s):  
Cancer Treatment ◽  
Induction Heating ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia

scholarly journals Iron Oxide Nanoparticle-Based Hyperthermia as a Treatment Option in Various Gastrointestinal Malignancies

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3013
Author(s):  
Julian Palzer ◽  
Lea Eckstein ◽  
Ioana Slabu ◽  
Oliver Reisen ◽  
Ulf P. Neumann ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cancer Treatment ◽  
Iron Oxide Nanoparticles ◽  
Magnetic Fluid ◽  
Photothermal Therapy ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles ◽  
Gastrointestinal Malignancies ◽  
Magnetic Fluid Hyperthermia ◽  
Oxide Nanoparticle

Iron oxide nanoparticle-based hyperthermia is an emerging field in cancer treatment. The hyperthermia is primarily achieved by two differing methods: magnetic fluid hyperthermia and photothermal therapy. In magnetic fluid hyperthermia, the iron oxide nanoparticles are heated by an alternating magnetic field through Brownian and Néel relaxation. In photothermal therapy, the hyperthermia is mainly generated by absorption of light, thereby converting electromagnetic waves into thermal energy. By use of iron oxide nanoparticles, this effect can be enhanced. Both methods are promising tools in cancer treatment and are, therefore, also explored for gastrointestinal malignancies. Here, we provide an extensive literature research on both therapy options for the most common gastrointestinal malignancies (esophageal, gastric and colorectal cancer, colorectal liver metastases, hepatocellular carcinoma, cholangiocellular carcinoma and pancreatic cancer). As many of these rank in the top ten of cancer-related deaths, novel treatment strategies are urgently needed. This review describes the efforts undertaken in vitro and in vivo.

Studies of zinc phthalocyanine/magnetic fluid complex as a bifunctional agent for cancer treatment

2005 ◽  
Vol 289 ◽  
pp. 476-479 ◽  
Author(s):  
D.M. Oliveira ◽  
P.P. Macaroff ◽  
K.F. Ribeiro ◽  
Z.G.M. Lacava ◽  
R.B. Azevedo ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Magnetic Fluid ◽  
Zinc Phthalocyanine
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