scholarly journals Induction Heating Analysis of Surface-Functionalized Nanoscale CoFe2O4 for Magnetic Fluid Hyperthermia toward Noninvasive Cancer Treatment

ACS Omega ◽  
2020 ◽  
Vol 5 (36) ◽  
pp. 23378-23384 ◽  
Author(s):  
Prashant B. Kharat ◽  
Sandeep B. Somvanshi ◽  
Pankaj P. Khirade ◽  
K. M. Jadhav
Keyword(s):  
Cancer Treatment ◽  
Induction Heating ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia

Study on Cancer Treatment using Magnetic Fluid for Medicine and Induction Heating Device

2013 ◽  
Vol 133 (6) ◽  
pp. 366-371 ◽  
Author(s):  
Hideo Nagae ◽  
Sotoshi Yamada ◽  
Yoshio Ikehata ◽  
Satoshi Yagitani ◽  
Isamu Nagano
Keyword(s):  
Cancer Treatment ◽  
Induction Heating ◽  
Magnetic Fluid ◽  
Heating Device

scholarly journals Iron Oxide Nanoparticle-Based Hyperthermia as a Treatment Option in Various Gastrointestinal Malignancies

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3013
Author(s):  
Julian Palzer ◽  
Lea Eckstein ◽  
Ioana Slabu ◽  
Oliver Reisen ◽  
Ulf P. Neumann ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cancer Treatment ◽  
Iron Oxide Nanoparticles ◽  
Magnetic Fluid ◽  
Photothermal Therapy ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles ◽  
Gastrointestinal Malignancies ◽  
Magnetic Fluid Hyperthermia ◽  
Oxide Nanoparticle

Iron oxide nanoparticle-based hyperthermia is an emerging field in cancer treatment. The hyperthermia is primarily achieved by two differing methods: magnetic fluid hyperthermia and photothermal therapy. In magnetic fluid hyperthermia, the iron oxide nanoparticles are heated by an alternating magnetic field through Brownian and Néel relaxation. In photothermal therapy, the hyperthermia is mainly generated by absorption of light, thereby converting electromagnetic waves into thermal energy. By use of iron oxide nanoparticles, this effect can be enhanced. Both methods are promising tools in cancer treatment and are, therefore, also explored for gastrointestinal malignancies. Here, we provide an extensive literature research on both therapy options for the most common gastrointestinal malignancies (esophageal, gastric and colorectal cancer, colorectal liver metastases, hepatocellular carcinoma, cholangiocellular carcinoma and pancreatic cancer). As many of these rank in the top ten of cancer-related deaths, novel treatment strategies are urgently needed. This review describes the efforts undertaken in vitro and in vivo.

scholarly journals Investigating the effect of outer layer of magnetic particles on cervical cancer cells HeLa by magnetic fluid hyperthermia

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Anand Bhardwaj ◽  
Neeraj Jain ◽  
Kinnari Parekh
Keyword(s):  
Cervical Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Induction Heating ◽  
Magnetic Fluid ◽  
Outer Layer ◽  
Magnetic Particles ◽  
Charged Fluid ◽  
Magnetic Fluid Hyperthermia ◽  
Cervical Cancer Cells

Abstract Background Magnetic fluid hyperthermia (MFH) is a successful nanotechnology application in recent decade where a biocompatible magnetic fluid is used to kill cancer cells in a controlled heating using AC magnetic field. In the present study, two ferrite-based magnetic fluids, with and without surfactant coating, were synthesized to study the effect of the outer layer of magnetic nanoparticles on cervical cancer cells. The magnetic fluid without surfactant coating (MFWI) was made stable by providing negative charge on the surface of each particle. On the other hand, lauric acid was used as a surfactant to have a stable dispersion of particles in aqueous media (MFWL). Methods The structural, magnetic properties and induction heating response of both the fluids were investigated using XRD, VSM, DLS, TGA, FTIR, and a high-frequency induction heater. The in vitro cytotoxicity of the synthesized fluids was observed on HeLa cells by performing MTT assay, and the effect of magnetic fluid hyperthermia was examined using Trypan blue assay. Results The crystallite size of surfactant stabilized particles was higher (11.0 ± 0.5 nm) compared to the charge stabilized particles (8.3 ± 0.5 nm). Induction heating experiments showed that the specific absorption rate of the surfactant-coated particles was almost double compared to ionic particle fluid. Magnetic fluid hyperthermia up to 1 hour at a concentration of 0.25 mg/mL of surfactant-coated magnetic fluid and 0.2 mg/mL concentration of charged fluid resulted in approximately 66 and 80% cell death, respectively, compared to untreated control cells. Conclusion The preliminary analysis of this study shows significant cell death due to hyperthermia, wherein MFWI revealed higher cytotoxicity compared to MFWL. Additional analysis into the role of the outer stabilizing layer on nanoparticle’s surface, concentration of nanoparticles, and hyperthermic duration is desirable to utilize MFH as a futuristic anti-cancer therapeutic tool.

Self-heating evaluation of superparamagnetic MnFe2O4 nanoparticles for magnetic fluid hyperthermia application towards cancer treatment

2020 ◽  
Vol 46 (16) ◽  
pp. 25576-25583 ◽  
Author(s):  
Supriya R. Patade ◽  
Deepali D. Andhare ◽  
Sandeep B. Somvanshi ◽  
Swapnil A. Jadhav ◽  
Mangesh V. Khedkar ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia ◽  
Self Heating ◽  
Mnfe2o4 Nanoparticles

Evaluation of new complexes of biocompatible magnetic fluid and third generation of photosensitizer useful to cancer treatment

2005 ◽  
Vol 41 (10) ◽  
pp. 4105-4107 ◽  
Author(s):  
P.P. Macaroff ◽  
D.M. Oliveira ◽  
K.F. Ribeiro ◽  
Z.G.M. Lacava ◽  
E.C.D. Lima ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Magnetic Fluid ◽  
Third Generation

On the in Vitro Hyperthermia of Magnetic Fluid in AC Magnetic Field

2009 ◽  
Author(s):  
Junfeng Jiang ◽  
Ruoyu Hong ◽  
Xiaohui Zhang ◽  
Hongzhong Li
Keyword(s):  
Magnetic Field ◽  
Magnetic Fluid ◽  
Volume Fraction ◽  
Maximum Temperature ◽  
Magnetic Fluid Hyperthermia ◽  
Ac Magnetic Field ◽  
Hyperthermia Therapy ◽  
Good Biocompatibility ◽  
High Chemical Stability

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.

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