Shape Statistics Variational Approach for the Outer Contour Segmentation of Left Ventricle MR Images

2006 ◽  
Vol 10 (3) ◽  
pp. 588-597 ◽  
Author(s):  
Q. Chen ◽  
Z.M. Zhou ◽  
M. Tang ◽  
P.A. Heng ◽  
D.S. Xia
2009 ◽  
Vol 20 (1) ◽  
pp. 30-40 ◽  
Author(s):  
Fu-Chang LIU ◽  
Qiang CHEN ◽  
Quan-Sen SUN ◽  
Pheng Ann HENG ◽  
De-Shen XIA

2009 ◽  
Author(s):  
Yingli Lu ◽  
Perry Radau ◽  
Kim Connelly ◽  
Alexander Dick ◽  
Graham Wright

This study investigates a fully automatic left ventricle segmentation method from cine short axis MR images. Advantages of this method include that it: 1) is image-driven and does not require manually drawn initial contours. 2) provides not only endocardial and epicardial contours, but also papillary muscles and trabeculations’ contours; 3) introduces a roundness measure that is fast and automatically locates the left ventricle; 4) simplifies the epicardial contour segmentation by mapping the pixels from Cartesian to approximately polar coordinates; and 5) applies a fast Fourier transform to smooth the endocardial and epicardial contours. Quantitative evaluation was performed on the 15 subjects of the MICCAI 2009 Cardiac MR Left Ventricle Segmentation hallenge. The average perpendicular distance between manually drawn and automatically selected contours over all slices, all studies, and two phases (end-diastole and end-systole) was 2.07 0.61 mm for endocardial and 1.91 0.63 mm for epicardial contours. These results indicate a promising method for automatic segmentation of left ventricle for clinical use.


2016 ◽  
Vol 138 (11) ◽  
Author(s):  
Ce Xi ◽  
Candace Latnie ◽  
Xiaodan Zhao ◽  
Ju Le Tan ◽  
Samuel T. Wall ◽  
...  

Patient-specific biventricular computational models associated with a normal subject and a pulmonary arterial hypertension (PAH) patient were developed to investigate the disease effects on ventricular mechanics. These models were developed using geometry reconstructed from magnetic resonance (MR) images, and constitutive descriptors of passive and active mechanics in cardiac tissues. Model parameter values associated with ventricular mechanical properties and myofiber architecture were obtained by fitting the models with measured pressure–volume loops and circumferential strain calculated from MR images using a hyperelastic warping method. Results show that the peak right ventricle (RV) pressure was substantially higher in the PAH patient (65 mmHg versus 20 mmHg), who also has a significantly reduced ejection fraction (EF) in both ventricles (left ventricle (LV): 39% versus 66% and RV: 18% versus 64%). Peak systolic circumferential strain was comparatively lower in both the left ventricle (LV) and RV free wall (RVFW) of the PAH patient (LV: −6.8% versus −13.2% and RVFW: −2.1% versus −9.4%). Passive stiffness, contractility, and myofiber stress in the PAH patient were all found to be substantially increased in both ventricles, whereas septum wall in the PAH patient possessed a smaller curvature than that in the LV free wall. Simulations using the PAH model revealed an approximately linear relationship between the septum curvature and the transseptal pressure gradient at both early-diastole and end-systole. These findings suggest that PAH can induce LV remodeling, and septum curvature measurements may be useful in quantifying transseptal pressure gradient in PAH patients.


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