Investigation on Pulse Wave Forward Peak Detection and Its Applications in Cardiovascular Health

2021 ◽  
pp. 1-1
Author(s):  
Lin Wanhua ◽  
Dingchang Zheng ◽  
Guanglin Li ◽  
Fei Chen ◽  
Hui Zhou
Keyword(s):  
Cardiovascular Health ◽  
Pulse Wave ◽  
Peak Detection ◽  
Forward Peak

scholarly journals Central and peripheral arterial stiffness responses to uninterrupted prolonged sitting combined with a high-fat meal: a randomized controlled crossover trial

2021 ◽  
Author(s):  
Simon Fryer ◽  
Keeron Stone ◽  
Craig Paterson ◽  
Meghan Brown ◽  
James Faulkner ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
High Fat ◽  
Low Fat ◽  
Peripheral Arterial ◽  
Fat Meal ◽  
Over Time

AbstractIndependently, prolonged uninterrupted sitting and the consumption of a meal high in saturated fats acutely disrupt normal cardiovascular function. Currently, the acute effects of these behaviors performed in combination on arterial stiffness, a marker of cardiovascular health, are unknown. This study sought to determine the effect of consuming a high-fat meal (Δ = 51 g fat) in conjunction with prolonged uninterrupted sitting (180 min) on measures of central and peripheral arterial stiffness. Using a randomized crossover design, 13 young healthy males consumed a high-fat (61 g) or low-fat (10 g) meal before 180 min of uninterrupted sitting. Carotid-femoral (cf) and femoral-ankle (fa) pulse wave velocity (PWV), aortic-femoral stiffness gradient (af-SG), superficial femoral PWV beta (β), and oscillometric pulse wave analysis outcomes were assessed pre and post sitting. cfPWV increased significantly more following the high-fat (mean difference [MD] = 0.59 m·s−1) meal than following the low-fat (MD = 0.2 m·s−1) meal, with no change in faPWV in either condition. The af-SG significantly decreased (worsened) (ηp2 = 0.569) over time in the high- and low-fat conditions (ratio = 0.1 and 0.1, respectively). Superficial femoral PWVβ significantly increased over time in the high- and low-fat conditions (ηp2 = 0.321; 0.8 and 0.4 m·s−1, respectively). Triglycerides increased over time in the high-fat trial only (ηp2 = 0.761). There were no significant changes in blood pressure. Consuming a high-fat meal prior to 180 min of uninterrupted sitting augments markers of cardiovascular disease risk more than consuming a low-fat meal prior to sitting.

scholarly journals Onset and Peak Detection over Pulse Wave Using Supervised SOM Network

2013 ◽  
pp. 133-137 ◽  
Author(s):  
A. Orjuela-Cañón ◽  
H. Posada-Quintero ◽  
D. Delisle-Rodríguez ◽  
M. Cuadra-Sanz ◽  
R. Fernández de la Vara-Prieto ◽  
...  
Keyword(s):  
Pulse Wave ◽  
Peak Detection ◽  
Som Network

scholarly journals Psychological Wellbeing and Aortic Stiffness

Hypertension ◽  
2020 ◽  
Vol 76 (3) ◽  
pp. 675-682
Author(s):  
Ai Ikeda ◽  
Andrew Steptoe ◽  
Martin Shipley ◽  
Ian B. Wilkinson ◽  
Carmel M. McEniery ◽  
...  
Keyword(s):  
Mixed Models ◽  
Aortic Stiffness ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Aortic Pulse Wave Velocity ◽  
Longitudinal Change ◽  
Lower Baseline ◽  
Subclinical Cardiovascular Disease ◽  
Eudaimonic Wellbeing

This study investigated 2 distinct aspects of positive wellbeing: affective wellbeing and eudaimonia with progression of aortic stiffness, an index of subclinical cardiovascular disease. A total of 4754 participants (mean age 65.3 years, 3466 men, and 1288 women) from the Whitehall II cohort study provided data on affective and eudaimonic wellbeing using subscales from the control, autonomy, self-realization and pleasure-19 questionnaire. Aortic stiffness was measured by aortic pulse wave velocity (PWV) at baseline (2008–2009) and 5 years later (2012–2013). Linear mixed models were used to measure the effect of affective and eudaimonic wellbeing on baseline PWV and 5-year PWV longitudinal change. A 1-SD higher eudaimonic wellbeing was associated with lower baseline PWV in men (β=−0.100 m/s [95% CI=−0.169 to −0.032]), independent of social, behavioral, and biological factors. This association persisted over 5 years. No such association was found in women (β=−0.029 m/s [95% CI=−0.126 to 0.069]). We did not find any association of positive wellbeing with change in PWV over time in either men or women. In older men, higher levels of eudaimonic wellbeing were associated with lower long-term levels of arterial stiffness. These findings support the notion that the pattern of association between positive wellbeing and cardiovascular health outcomes involves eudaimonic rather than affective wellbeing and is sex-specific.

scholarly journals Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study

2015 ◽  
Vol 114 (8) ◽  
pp. 1246-1255 ◽  
Author(s):  
Roberto Sansone ◽  
Ana Rodriguez-Mateos ◽  
Jan Heuel ◽  
David Falk ◽  
Dominik Schuler ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Pulse Wave Velocity ◽  
Endothelial Function ◽  
Cardiovascular Health ◽  
Framingham Risk Score ◽  
Pulse Wave ◽  
Men And Women ◽  
Framingham Risk ◽  
Randomised Controlled

AbstractCocoa flavanol (CF) intake improves endothelial function in patients with cardiovascular risk factors and disease. We investigated the effects of CF on surrogate markers of cardiovascular health in low risk, healthy, middle-aged individuals without history, signs or symptoms of CVD. In a 1-month, open-label, one-armed pilot study, bi-daily ingestion of 450 mg of CF led to a time-dependent increase in endothelial function (measured as flow-mediated vasodilation (FMD)) that plateaued after 2 weeks. Subsequently, in a randomised, controlled, double-masked, parallel-group dietary intervention trial (Clinicaltrials.gov: NCT01799005), 100 healthy, middle-aged (35–60 years) men and women consumed either the CF-containing drink (450 mg) or a nutrient-matched CF-free control bi-daily for 1 month. The primary end point was FMD. Secondary end points included plasma lipids and blood pressure, thus enabling the calculation of Framingham Risk Scores and pulse wave velocity. At 1 month, CF increased FMD over control by 1·2 % (95 % CI 1·0, 1·4 %). CF decreased systolic and diastolic blood pressure by 4·4 mmHg (95 % CI 7·9, 0·9 mmHg) and 3·9 mmHg (95 % CI 6·7, 0·9 mmHg), pulse wave velocity by 0·4 m/s (95 % CI 0·8, 0·04 m/s), total cholesterol by 0·20 mmol/l (95 % CI 0·39, 0·01 mmol/l) and LDL-cholesterol by 0·17 mmol/l (95 % CI 0·32, 0·02 mmol/l), whereas HDL-cholesterol increased by 0·10 mmol/l (95 % CI 0·04, 0·17 mmol/l). By applying the Framingham Risk Score, CF predicted a significant lowering of 10-year risk for CHD, myocardial infarction, CVD, death from CHD and CVD. In healthy individuals, regular CF intake improved accredited cardiovascular surrogates of cardiovascular risk, demonstrating that dietary flavanols have the potential to maintain cardiovascular health even in low-risk subjects.

EVALUATION INDEX OF ADULT MALE BLOOD VESSEL AGE-BASED ON PULSE WAVE WAVEFORM CHARACTERISTIC PARAMETERS

2019 ◽  
Vol 19 (08) ◽  
pp. 1940057 ◽  
Author(s):  
LEI WANG ◽  
LINLIN WANG ◽  
QIAN LI ◽  
WENLU ZHANG ◽  
YAN WANG
Keyword(s):  
Cardiovascular Disease ◽  
Blood Vessel ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Age Groups ◽  
Health Assessment ◽  
Cerebrovascular Diseases ◽  
Age Difference ◽  
Time Ratio ◽  
Highly Correlated

The aim of this study was to find a non-invasive pulse wave waveform index that was highly correlated with cardiovascular disease and to establish an effective model for cardiovascular health assessment in middle-aged men to provide early warning of possible cardiovascular and cerebrovascular diseases. Considering the characteristics of pulse wave easy to detect and rich physiological information, the paper collected pulse waves of healthy males at six age groups, and collected 50 samples per age group. The pulse wave waveform parameters of each sample were extracted, including inflow time, outflow time, total beat time, fast inflow time, inflow time ratio and waveform coefficient [Formula: see text] value, the differences of which in different age groups were analyzed. Stepwise regression analysis was used to establish the relationship between age and pulse waveform parameters. The results show that the indicators of inflow time, inflow time ratio and fast inflow time have obvious differences with age, and with the increase of age, these three indicators show a steady upward trend. The indicators of outflow time, total beat time, and waveform coefficient are not sensitive to age changes. A predictive model of vessel age was established: [Formula: see text] time ([Formula: see text]). The pulse wave inflow time of hypertensive patients was substituted into the above-mentioned model, and the calculated blood vessel age was greater than the actual age. The age difference is greater than 5 years old. This study suggests that the pulse wave parameters of inflow time, fast inflow time and inflow time ratio has a significant and stable trend with age, indicating that they are closely related to vascular elasticity, compliance and stiffness, and can be used as predictors of cardiovascular disease.

scholarly journals Cardiometabolic Health in Relation to Lifestyle and Body Weight Changes 3–8 Years Earlier

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1953 ◽  
Author(s):  
Tessa Van Elten ◽  
Mireille. Van Poppel ◽  
Reinoud Gemke ◽  
Henk Groen ◽  
Annemieke Hoek ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Body Weight ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Cardiometabolic Health ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Infertile Women

The degree to which individuals change their lifestyle in response to interventions differs and this variation could affect cardiometabolic health. We examined if changes in dietary intake, physical activity and weight of obese infertile women during the first six months of the LIFEstyle trial were associated with cardiometabolic health 3–8 years later (N = 50–78). Lifestyle was assessed using questionnaires and weight was measured at baseline, 3 and 6 months after randomization. BMI, blood pressure, body composition, pulse wave velocity, glycemic parameters and lipid profile were assessed 3–8 years after randomization. Decreases in savory and sweet snack intake were associated with lower HOMA-IR 3–8 years later, but these associations disappeared after adjustment for current lifestyle. No other associations between changes in lifestyle or body weight during the first six months after randomization with cardiovascular health 3–8 years later were observed. In conclusion, reductions in snack intake were associated with reduced insulin resistance 3–8 years later, but adjustment for current lifestyle reduced these associations. This indicates that changing lifestyle is an important first step, but maintaining this change is needed for improving cardiometabolic health in the long-term.

Arteriosclerosis, Atherosclerosis, and Cardiovascular Health: Joint Relations to the Incidence of Cardiovascular Disease

Hypertension ◽  
2021 ◽  
Author(s):  
Ramachandran S. Vasan ◽  
Stephanie Pan ◽  
Martin G. Larson ◽  
Gary F. Mitchell ◽  
Vanessa Xanthakis
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Artery ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Subclinical Atherosclerosis ◽  
Fasting Blood Glucose ◽  
Study Cohort ◽  
Increased Risk

Aging is associated with an increased prevalence of subclinical atherosclerosis and stiffening of the arterial walls (arteriosclerosis). These 2 coexisting conditions are mitigated by the presence of ideal cardiovascular health (optimal levels of fasting blood glucose, cholesterol, resting blood pressure, body mass index, no smoking, good dietary quality, and regular physical activity). We hypothesized that the concomitant presence of subclinical atherosclerosis (coronary artery calcification), arteriosclerosis (higher carotid-femoral pulse wave velocity), and suboptimal cardiovascular health is associated with increased risk of cardiovascular disease relative to the absence of these 3 conditions. We tested our hypothesis in the community-based Framingham Heart Study cohort (N=2580, mean age 52 years, 49% women). We classified participants based on (1) the presence versus absence of coronary artery calcium; (2) higher (>sex-specific median) carotid-femoral pulse wave velocity; (3) poor cardiovascular health (score 0–7). Thus, participants could have no abnormalities (referent group), 1, 2, or 3 suboptimal measures. We used Cox regression to relate the number of suboptimal measures (0–3) to the incidence of cardiovascular disease during follow-up (median 14 years). Cardiovascular disease incidence rates/1000 person-years in groups with 0 to 3 suboptimal measures were 1.93 (95% CI, 1.28–2.90), 4.68 (95% CI, 3.48–6.29), 8.93 (95% CI, 6.99–11.41), and 18.26 (95% CI, 14.65–22.77), respectively. Compared with the group with no abnormalities, corresponding multivariable-adjusted hazards ratios for cardiovascular disease were 1.81, 2.18, and 3.71, respectively ( P <0.05 for all). Our observations suggest that the conjoint presence of atherosclerosis, arteriosclerosis, and poor cardiovascular health substantially elevates cardiovascular disease risk, whereas their absence denotes low risk.

Chronic Standing Desk Use and Arterial Stiffness

2019 ◽  
Vol 16 (11) ◽  
pp. 1022-1028
Author(s):  
Ian M. Greenlund ◽  
Piersan E. Suriano ◽  
Steven J. Elmer ◽  
Jason R. Carter ◽  
John J. Durocher
Keyword(s):  
Cardiovascular Disease ◽  
Body Mass Index ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Body Mass ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Sedentary Time ◽  
Secondary Analysis ◽  
Chronic Effects

Background: Sedentary activity and sitting for at least 10 hours per day can increase the risk for cardiovascular disease by more than 60%. Use of standing desks may decrease sedentary time and improve cardiovascular health. Acute standing lowers pulse wave velocity (PWV), but chronic effects remain unknown. The purpose of this study was to determine the effect of chronic standing desk use on arterial stiffness versus seated controls. Methods: A total of 48 adults participated in this study. Twenty-four participants qualified as seated desk users (age 41 [10] y, body mass index 25 [4] kg/m2) and 24 as standing desk users (age 45 [12] y, body mass index 25 [5] kg/m2). Arterial stiffness was assessed as PWV within the aorta, arm, and leg. Results: Carotid–femoral PWV (cfPWV) was not different between seated (6.6 [1.3] m/s) and standing (6.9 [1.3] m/s) groups (P = .47). Similarly, there were no differences in arm or leg PWV between groups (P = .13 and P = .66, respectively). A secondary analysis of traditional factors of age and aerobic fitness revealed significant differences in cfPWV in seated and standing desk participants. Age also significantly influenced cfPWV across conditions. Conclusions: Standing for >50% of a workday did not affect PWV. Consistent with previous research, fitness and age are important modulators of arterial stiffness.

scholarly journals The Effects of a Simulated Workday of Prolonged Sitting on Seated versus Supine Blood Pressure and Pulse Wave Velocity in Adults with Overweight/Obesity and Elevated Blood Pressure

2020 ◽  
Vol 57 (6) ◽  
pp. 355-366
Author(s):  
Abdullah Bandar Alansare ◽  
Robert J. Kowalsky ◽  
Melissa A. Jones ◽  
Sophy J. Perdomo ◽  
Lee Stoner ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Mixed Models ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Effect Sizes ◽  
Radial Pulse ◽  
Prolonged Sitting ◽  
Main Effects

We evaluated the effects of a simulated workday of prolonged sitting on blood pressure (BP) and pulse wave velocity (PWV) and examined whether posture (seated vs. supine) affected responses. Participants (<i>n</i> = 25) were adults, with overweight/obesity and elevated BP, and performed seated desk work for 7.5 h. BP and PWV were measured in seated and supine postures at baseline (7:15 a.m.), midday (12:05 p.m.), and afternoon (4:45 p.m.). Generalized linear mixed models evaluated the effects of prolonged sitting on BP and PWV within each posture and interactions by posture and sex. In the recommended postures, seated BP and supine carotid-femoral pulse wave velocity (cfPWV) and carotid-ankle pulse wave velocity (caPWV), but not carotid-radial pulse wave velocity (crPWV), significantly increased over the simulated seated workday (all <i>p</i> &#x3c; 0.05; effect sizes [<i>d</i>] ranged from 0.25 to 0.44). Whilst no posture-by-time interactions were observed (<i>p</i> &#x3e; 0.05), BP, caPWV, and crPWV were higher when seated versus supine (main effects of posture <i>p</i> &#x3c; 0.05; <i>d</i> ranged from 0.30 to 1.04). Exploratory analysis revealed that females had greater seated BP responses (<i>p</i> for interaction &#x3c;0.05); seated PWV and supine BP and PWV responses were similar by sex (<i>p</i> for interaction &#x3e;0.05). A simulated workday of prolonged sitting increased seated BP and supine cfPWV and caPWV, and posture minimally influenced these responses. These results add to the evidence suggesting a deleterious effect of prolonged sitting on cardiovascular health.

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