Numerical Study of Enhancement of Positive Dielectrophoresis Particle Trapping in Electrode-Multilayered Microfluidic Device

2019 ◽  
Vol 66 (10) ◽  
pp. 2936-2944 ◽  
Author(s):  
Norikazu Sato ◽  
Jiafeng Yao ◽  
Daisuke Kawashima ◽  
Masahiro Takei
Keyword(s):  
Microfluidic Device ◽  
Numerical Study ◽  
Particle Trapping ◽  
Positive Dielectrophoresis

scholarly journals Hydrodynamic Trapping of Particles in an Expansion-Contraction Microfluidic Device

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ruijin Wang
Keyword(s):  
Reynolds Number ◽  
Microfluidic Device ◽  
Hot Spot ◽  
Force Balance ◽  
Trapping Efficiency ◽  
Particle Sizes ◽  
Particle Trapping ◽  
Particle Reynolds Number ◽  
Drag Forces ◽  
Hydrodynamic Effects

Manipulation and sorting of particles utilizing microfluidic phenomena have been a hot spot in recent years. Here, we present numerical investigations on particle trapping techniques by using intrinsic hydrodynamic effects in an expansion-contraction microfluidic device. One emphasis is on the underlying fluid dynamical mechanisms causing cross-streamlines migration of the particles in shear and vortical flows. The results show us that the expansion-contraction geometric structure is beneficial to particle trapping according to its size. Particle Reynolds number and aspect ratio of the channel will influence the trapping efficiency greatly because the force balance between inertial lift and vortex drag forces is the intrinsic reason. Especially, obvious inline particles contribution presented when the particle Reynolds number being unit. In addition, we selected three particle sizes (2, 7, and 15 μm) to examine the trapping efficiency.

Influence of geometry and material of insulating posts on particle trapping using positive dielectrophoresis

2017 ◽  
Vol 1483 ◽  
pp. 127-137 ◽  
Author(s):  
Georg R. Pesch ◽  
Fei Du ◽  
Michael Baune ◽  
Jorg Thöming
Keyword(s):  
Particle Trapping ◽  
Positive Dielectrophoresis

scholarly journals Modeling a Dielectrophoretic Microfluidic Device with Vertical Interdigitated Transducer Electrodes for Separation of Microparticles Based on Size

Micromachines ◽  
2020 ◽  
Vol 11 (6) ◽  
pp. 563 ◽  
Author(s):  
Fadi Alnaimat ◽  
Bobby Mathew ◽  
Ali Hilal-Alnaqbi
Keyword(s):  
Mathematical Model ◽  
Microfluidic Device ◽  
Separation Efficiency ◽  
Equations Of Motion ◽  
Volumetric Flow Rate ◽  
Flow Profile ◽  
Heterogeneous Mixture ◽  
Electric Voltage ◽  
Positive Dielectrophoresis ◽  
The Mathematical Model

This article conceptualizes and mathematically models a dielectrophoretic microfluidic device with two sets of interdigitated transducer vertical electrodes for separation of a binary heterogeneous mixture of particles based on size; each set of electrodes is located on the sidewalls and independently controllable. To achieve separation in the proposed microfluidic device, the small microparticles are subjected to positive dielectrophoresis and the big microparticles do not experience dielectrophoresis. The mathematical model consists of equations describing the motion of each microparticle, fluid flow profile, and electric voltage and field profiles, and they are solved numerically. The equations of motion take into account the influence of phenomena, such as inertia, drag, dielectrophoresis, gravity, and buoyancy. The model is used for a parametric study to understand the influence of parameters on the performance of the microfluidic device. The parameters studied include applied electric voltages, electrode dimensions, volumetric flow rate, and number of electrodes. The separation efficiency of the big and small microparticles is found to be independent of and dependent on all parameters, respectively. On the other hand, the separation purity of the big and small microparticles is found to be dependent on and independent of all parameters, respectively. The mathematical model is useful in designing the proposed microfluidic device with the desired level of separation efficiency and separation purity.

Biological Fluid Separation in Microfluidic Channels Using Flow Rate Control

2005 ◽  
Author(s):  
Sung Yang ◽  
Akif U¨ndar ◽  
Jeffrey D. Zahn
Keyword(s):  
Blood Plasma ◽  
Real Time ◽  
Microfluidic Device ◽  
Numerical Study ◽  
Biological Fluid ◽  
Microfluidic Channels ◽  
Defibrinated Sheep Blood ◽  
Plasma Separation ◽  
Study Results ◽  
Blood Plasma Separation

A microfluidic device for continuous, real time blood plasma separation is introduced. This device is composed of a blood inlet, a purified plasma outlet, and a concentrated blood cell outlet. It is designed to separate blood plasma from an initial blood sample of up to 45 % hematocrit (Hct). The microfluidic device is designed and analyzed using an analogous electrical circuit, analytical and numerical studies. The numerical study results show that 27 % and 25 % of plasma volume can be separated from a total inlet blood volume of 45 % and 39 % hematocrit, respectively. The functionality of this device was demonstrated using defibrinated sheep blood (Hct=36 %). During 2 hrs. of continuous blood infusion through the device, all the blood cells traveled through the device toward the concentrated blood outlet while only the plasma flowed towards the plasma outlet without any clogging or lysis of cells. The experimentally measured plasma skimming volume was about 33 % for a 36 % inlet hematocrit. Due to the device’s simple structure and control mechanism, this microdevice is expected to be used for highly efficient continuous, real time cell-free blood plasma separation device.

scholarly journals A microfluidic device to sort capsules by deformability: a numerical study

Soft Matter ◽  
2014 ◽  
Vol 10 (39) ◽  
pp. 7705-7711 ◽  
Author(s):  
Lailai Zhu ◽  
Cecilia Rorai ◽  
Dhrubaditya Mitra Dhrubaditya Mitra ◽  
Luca Brandt
Keyword(s):  
Numerical Simulations ◽  
Microfluidic Device ◽  
Numerical Study ◽  
Elastic Capsules

Guided by extensive numerical simulations, we propose a microfluidic device that can sort elastic capsules by their deformability.

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