Electrical Stimulation with Pt Electrodes: AMethod for Determination of "Real" Electrode Areas

1977 ◽  
Vol BME-24 (5) ◽  
pp. 436-439 ◽  
Author(s):  
S. B. Brummer ◽  
M. J. Turner
1962 ◽  
Vol 39 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Roger A. Gorski ◽  
Charles A. Barraclough

ABSTRACT We have previously suggested that the failure of the androgen-sterilized, persistent-oestrous rat to ovulate, following electrical stimulation of the median eminence structures of the hypothalamus, is due to an insufficiency in adenohypophyseal LH concentration. Using the ovarian ascorbic acid technique for quantitative determination of pituitary LH content, the present studies have demonstrated that the sterile rat pituitary gland contains one-third the LH content of the normal prooestrous gland. Furthermore, not only does progesterone priming of this persistent-oestrous rat result in a 75 % increase in LH concentration, but on hypothalamic stimulation sufficient LH is released to induce ovulation. The decrease in LH concentration which accompanies ovulation in the progesterone-primed, sterile rat is approximately 45 % of the total gland content as compared with a 51 % decrease in pituitary content in the normal cyclic rat.


2021 ◽  
Author(s):  
S.S. Ananiev ◽  
D.A. Pavlov ◽  
R.N. Yakupov ◽  
V.A. Golodnova ◽  
M.V. Balykin

The study was conducted on 22 healthy men aged 18-23 years. The primary motor cortex innervating the lower limb was stimulated with transcranial magnetic stimulation. Using transcutaneous electrical stimulation of the spinal cord, evoked motor responses of the muscles of the lower extremities were initiated when electrodes were applied cutaneous between the spinous processes in the Th11-Th12 projection. Research protocol: Determination of the thresholds of BMO of the muscles of the lower extremities during TESCS; determination of the BMO threshold of the TA muscle in TMS; determination of the thresholds of the BMO of the muscles of the lower extremities during TESCS against the background of 80% and 90% TMS. It was found that magnetic stimulation of the motor cortex of the brain leads to an increase in the excitability of the neural structures of the lumbar thickening of the spinal cord and an improvement in neuromuscular interactions. Key words: transcranial magnetic stimulation, transcutaneous electrical stimulation of the spinal cord, neural networks, excitability, neuromuscular interactions.


Author(s):  
A. Baniya ◽  
S. Thapa ◽  
E. Borquist ◽  
D. Bailey ◽  
D. Wood ◽  
...  

Hydrogen sulfide (H2S) is rapidly emerging as a biologically significant signaling molecule. In recent studies, sulfide level in blood or plasma has been reported to be in the concentration between 10 and 300 μM suggesting it acts in various diseases. This work reports progress on a new Lab-on-a-Chip (LOC) device for these applications. The uniquely designed, hand-held device uses advanced liberation chemistry that releases H2S from liquid sample and an electrochemical approach to detect sulfide concentration from the aqueous solution. The device itself consists of three distinct layers of Polydimethylsiloxane (PDMS) structures and a three electrode system for direct and rapid H2S concentration measurement. In this work specifically, the oxidation of sulfide at the gold (Au) and platinum (Pt.) electrodes has been examined. This is the first known application of electrochemical H2S sensing in an LOC application. The analytical utility and performance of the device has been assessed through direct detection using chronoamperometry (CA) scan and cyclic voltammetry (CV). An electrocatalytic sulfide oxidation signal has been recorded for sulfide concentration range vs, Ag/AgCl at different pH buffers at the trapping chamber. The calibration curve in the range 1 μM to 1 M was obtained using this electrode setup. The detection limit was found to be 0.1 μM. This device shows promise for providing fast and inexpensive determination of H2S concentration in aqueous samples.


1993 ◽  
Vol 76 (6) ◽  
pp. 1310-1312 ◽  
Author(s):  
Michael J. Laster ◽  
Jin Liu ◽  
Edmond I. Eger ◽  
Shahram Taheri

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